| A feedforward mechanism mediated by mechanosensitive ion channel PIEZO1 and tissue mechanics promotes glioma aggression X Chen, S Wanggou, A Bodalia, M Zhu, W Dong, JJ Fan, WC Yin, HK Min, ... Neuron 100 (4), 799-815. e7, 2018 | 271 | 2018 |
| Failure of human rhombic lip differentiation underlies medulloblastoma formation LD Hendrikse, P Haldipur, O Saulnier, J Millman, AH Sjoboen, ... Nature 609 (7929), 1021-1028, 2022 | 66 | 2022 |
| Chloride intracellular channel 1 cooperates with potassium channel EAG2 to promote medulloblastoma growth MA Francisco, S Wanggou, JJ Fan, W Dong, X Chen, A Momin, ... Journal of Experimental Medicine 217 (5), 2020 | 31 | 2020 |
| Identification of small-molecule ion channel modulators in C. elegans channelopathy models Q Jiang, K Li, WJ Lu, S Li, X Chen, XJ Liu, J Yuan, Q Ding, F Lan, SQ Cai Nature Communications 9 (1), 3941, 2018 | 17 | 2018 |
| Channeling force in the brain: mechanosensitive ion channels choreograph mechanics and malignancies A Momin, S Bahrampour, HK Min, X Chen, X Wang, Y Sun, X Huang Trends in pharmacological sciences 42 (5), 367-384, 2021 | 16 | 2021 |
| Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes X Wang, Z Gong, T Wang, J Law, X Chen, S Wanggou, J Wang, B Ying, ... Science Advances 9 (13), eade5321, 2023 | 14 | 2023 |
| Microrobotic swarms for intracellular measurement with enhanced signal-to-noise ratio X Wang, T Wang, X Chen, J Law, G Shan, W Tang, Z Gong, P Pan, X Liu, ... ACS nano 16 (7), 10824-10839, 2022 | 14 | 2022 |
| Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity X Chen, A Momin, S Wanggou, X Wang, HK Min, W Dou, Z Gong, J Chan, ... Neuron 111 (1), 30-48. e14, 2023 | 13 | 2023 |
| Quantitative selection of single human sperm with high DNA integrity for intracytoplasmic sperm injection Z Zhang, C Dai, G Shan, X Chen, H Liu, K Abdalla, I Kuznyetsova, ... Fertility and Sterility 116 (5), 1308-1318, 2021 | 13 | 2021 |
| The DEAD-box helicase DDX56 is a conserved stemness regulator in normal and cancer stem cells M Pryszlak, M Wiggans, X Chen, JE Jaramillo, SE Burns, LM Richards, ... Cell reports 34 (13), 2021 | 12 | 2021 |
| KChIP-like auxiliary subunits of Kv4 channels regulate excitability of muscle cells and control male turning behavior during mating in Caenorhabditis elegans X Chen, MY Ruan, SQ Cai Journal of Neuroscience 35 (5), 1880-1891, 2015 | 7 | 2015 |
| Ultrathin and flexible bioelectronic arrays for functional measurement of iPSC-cardiomyocytes under cardiotropic drug administration and controlled microenvironments W Dou, A Daoud, X Chen, T Wang, M Malhi, Z Gong, F Mirshafiei, M Zhu, ... Nano Letters 23 (6), 2321-2331, 2023 | 5 | 2023 |
| A designer peptide against the EAG2–Kvβ2 potassium channel targets the interaction of cancer cells and neurons to treat glioblastoma W Dong, A Fekete, X Chen, H Liu, GL Beilhartz, X Chen, S Bahrampour, ... Nature Cancer 4 (10), 1418-1436, 2023 | 3 | 2023 |
| Pan-cancer analysis of the ion permeome reveals functional regulators of glioblastoma aggression AT Bahcheli, HK Min, M Bayati, W Dong, A Fortuna, H Zhao, I Dzneladze, ... bioRxiv, 2023.04. 07.536030, 2023 | 2 | 2023 |
| Integration of single-cell regulon atlas and multi-omics data for prognostic stratification and personalized treatment prediction in human lung adenocarcinoma Y Xiong, Y Zhang, N Liu, Y Li, H Liu, Q Yang, Y Chen, Z Xia, X Chen, ... Journal of Translational Medicine 21 (1), 499, 2023 | 1 | 2023 |
| Pan-cancer ion transport signature reveals functional regulators of glioblastoma aggression AT Bahcheli, HK Min, M Bayati, H Zhao, A Fortuna, W Dong, I Dzneladze, ... The EMBO Journal 43 (2), 196-224, 2024 | | 2024 |
| Indentation induces instantaneous nuclear stiffening and unfolding of nuclear envelope wrinkles W Tang, X Chen, X Wang, M Zhu, G Shan, T Wang, W Dou, J Wang, ... Proceedings of the National Academy of Sciences 120 (36), e2307356120, 2023 | | 2023 |
| Directed differentiation of human hindbrain neuroepithelial stem cells recapitulates cerebellar granule neurogenesis BM Dave, X Chen, F McCready, CS Charton, RM Morley, JK Tailor, J Ellis, ... Development 150 (13), 2023 | | 2023 |
| A computation model of the multi-layer brain-tumor-blood barrier structure under mechanical load X Wang, X Chen, S Bajic, Y Sun, X Huang Biophysical Journal 122 (3), 285a, 2023 | | 2023 |
| Automechanical gating of Piezo1 triggers the fusogenic steps in macropinocytosis S Freeman, R Cai, X Chen, X Huang | | 2022 |
Xi HuangThe Hospital for Sick Children / University of TorontoVerified email at sickkids.ca
