ATP‐binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain N Wang, L Yvan‐Charvet, D Lütjohann, M Mulder, T Vanmierlo, TW Kim, ... The FASEB Journal 22 (4), 1073-1082, 2008 | 221 | 2008 |
Liver X receptor activation restores memory in aged AD mice without reducing amyloid T Vanmierlo, K Rutten, J Dederen, VW Bloks, F Kuipers, A Kiliaan, ... Neurobiology of aging 32 (7), 1262-1272, 2011 | 158 | 2011 |
Plant-based sterols and stanols in health & disease:“Consequences of human development in a plant-based environment?” J Plat, S Baumgartner, T Vanmierlo, D Lütjohann, KL Calkins, DG Burrin, ... Progress in lipid research 74, 87-102, 2019 | 153 | 2019 |
Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study VK Burg, HS Grimm, TL Rothhaar, S Grösgen, B Hundsdörfer, ... Journal of Neuroscience 33 (41), 16072-16087, 2013 | 153 | 2013 |
GEBR‐7b, a novel PDE4D selective inhibitor that improves memory in rodents at non‐emetic doses O Bruno, E Fedele, J Prickaerts, LA Parker, E Canepa, C Brullo, ... British journal of pharmacology 164 (8), 2054-2063, 2011 | 150 | 2011 |
Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function JK Kruit, N Wijesekara, C Westwell-Roper, T Vanmierlo, W De Haan, ... Diabetes 61 (3), 659-664, 2012 | 141 | 2012 |
Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D ASR Sierksma, DLA Van Den Hove, F Pfau, M Philippens, O Bruno, ... Neuropharmacology 77, 120-130, 2014 | 138 | 2014 |
Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders J Spaas, L Van Veggel, M Schepers, A Tiane, J Van Horssen, ... Cellular and Molecular Life Sciences 78 (10), 4615-4637, 2021 | 136 | 2021 |
Dietary intake of plant sterols stably increases plant sterol levels in the murine brain T Vanmierlo, O Weingärtner, S van der Pol, C Husche, A Kerksiek, ... Journal of lipid research 53 (4), 726-735, 2012 | 125 | 2012 |
Dietary plant sterols accumulate in the brain PJ Jansen, D Lütjohann, K Abildayeva, T Vanmierlo, T Plösch, J Plat, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2006 | 121 | 2006 |
Improved long-term memory via enhancing cGMP-PKG signaling requires cAMP-PKA signaling E Bollen, D Puzzo, K Rutten, L Privitera, J De Vry, T Vanmierlo, G Kenis, ... Neuropsychopharmacology 39 (11), 2497-2505, 2014 | 120 | 2014 |
High fat diet exacerbates neuroinflammation in an animal model of multiple sclerosis by activation of the renin angiotensin system S Timmermans, JFJ Bogie, T Vanmierlo, D Lütjohann, P Stinissen, ... Journal of neuroimmune pharmacology 9 (2), 209-217, 2014 | 115 | 2014 |
The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses T Vanmierlo, P Creemers, S Akkerman, M van Duinen, A Sambeth, ... Behavioural Brain Research 303, 26-33, 2016 | 114 | 2016 |
Myelin alters the inflammatory phenotype of macrophages by activating PPARs JFJ Bogie, W Jorissen, J Mailleux, PG Nijland, N Zelcer, T Vanmierlo, ... Acta neuropathologica communications 1, 1-13, 2013 | 100 | 2013 |
From OPC to oligodendrocyte: an epigenetic journey A Tiane, M Schepers, B Rombaut, R Hupperts, J Prickaerts, N Hellings, ... Cells 8 (10), 1236, 2019 | 97 | 2019 |
Plant sterols: Friend or foe in CNS disorders? T Vanmierlo, JFJ Bogie, J Mailleux, J Vanmol, D Lütjohann, M Mulder, ... Progress in lipid research 58, 26-39, 2015 | 92 | 2015 |
Methylglyoxal-derived advanced glycation endproducts in multiple sclerosis S Wetzels, K Wouters, CG Schalkwijk, T Vanmierlo, JJA Hendriks International journal of molecular sciences 18 (2), 421, 2017 | 86 | 2017 |
Progress and perspectives in plant sterol and plant stanol research PJH Jones, M Shamloo, DS MacKay, TC Rideout, SB Myrie, J Plat, ... Nutrition reviews 76 (10), 725-746, 2018 | 77 | 2018 |
7, 8-Dihydroxyflavone improves memory consolidation processes in rats and mice E Bollen, T Vanmierlo, S Akkerman, C Wouters, HMW Steinbusch, ... Behavioural brain research 257, 8-12, 2013 | 73 | 2013 |
Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model J Bogie, C Hoeks, M Schepers, A Tiane, A Cuypers, F Leijten, ... Scientific Reports 9 (1), 4908, 2019 | 72 | 2019 |