The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis MH Zaki, KL Boyd, P Vogel, MB Kastan, M Lamkanfi, TD Kanneganti Immunity 32 (3), 379-391, 2010 | 1048 | 2010 |
Inflammasome is a central player in the induction of obesity and insulin resistance R Stienstra, JA Van Diepen, CJ Tack, MH Zaki, FL Van De Veerdonk, ... Proceedings of the National Academy of Sciences 108 (37), 15324-15329, 2011 | 777 | 2011 |
IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation MH Zaki, P Vogel, M Body-Malapel, M Lamkanfi, TD Kanneganti The Journal of immunology 185 (8), 4912-4920, 2010 | 445 | 2010 |
The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis MH Zaki, P Vogel, RKS Malireddi, M Body-Malapel, PK Anand, J Bertin, ... Cancer cell 20 (5), 649-660, 2011 | 422 | 2011 |
Protein S-guanylation by the biological signal 8-nitroguanosine 3′, 5′-cyclic monophosphate T Sawa, MH Zaki, T Okamoto, T Akuta, Y Tokutomi, S Kim-Mitsuyama, ... Nature chemical biology 3 (11), 727-735, 2007 | 304 | 2007 |
SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway S Khan, MS Shafiei, C Longoria, JW Schoggins, RC Savani, H Zaki Elife 10, e68563, 2021 | 301 | 2021 |
The Nlrp3 inflammasome: contributions to intestinal homeostasis MH Zaki, M Lamkanfi, TD Kanneganti Trends in immunology 32 (4), 171-179, 2011 | 294 | 2011 |
Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice S Khan, S Waliullah, V Godfrey, MAW Khan, RA Ramachandran, ... Science translational medicine 12 (567), eaay6218, 2020 | 212 | 2020 |
Role of inflammasomes in host defense against Citrobacter rodentium infection Z Liu, MH Zaki, P Vogel, P Gurung, BB Finlay, W Deng, M Lamkanfi, ... Journal of Biological chemistry 287 (20), 16955-16964, 2012 | 160 | 2012 |
Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection MH Zaki, SM Man, P Vogel, M Lamkanfi, TD Kanneganti Proceedings of the National Academy of Sciences 111 (1), 385-390, 2014 | 149 | 2014 |
Nitric oxide-induced nitrative stress involved in microbial pathogenesis MH Zaki, T Akuta, T Akaike Journal of pharmacological sciences 98 (2), 117-129, 2005 | 144 | 2005 |
The DNA sensor AIM2 maintains intestinal homeostasis via regulation of epithelial antimicrobial host defense S Hu, L Peng, YT Kwak, EME Tekippe, C Pasare, JS Malter, LV Hooper, ... Cell reports 13 (9), 1922-1936, 2015 | 118 | 2015 |
The NLRP12 sensor negatively regulates autoinflammatory disease by modulating interleukin-4 production in T cells JR Lukens, P Gurung, PJ Shaw, MJ Barr, MH Zaki, SA Brown, P Vogel, ... Immunity 42 (4), 654-664, 2015 | 116 | 2015 |
Seroepidemiology of hepatitis B and delta virus infections in Bangladesh MH Zaki, GL Darmstadt, A Baten, CR Ahsan, SK Saha Journal of tropical pediatrics 49 (6), 371-374, 2003 | 96 | 2003 |
LncRNA HOTAIR regulates lipopolysaccharide-induced cytokine expression and inflammatory response in macrophages M Obaid, SMN Udden, P Deb, N Shihabeddin, MH Zaki, SS Mandal Scientific reports 8 (1), 15670, 2018 | 93 | 2018 |
NOD2 suppresses colorectal tumorigenesis via downregulation of the TLR pathways SMN Udden, L Peng, JL Gan, JM Shelton, JS Malter, LV Hooper, MH Zaki Cell reports 19 (13), 2756-2770, 2017 | 85 | 2017 |
Cytoprotective function of heme oxygenase 1 induced by a nitrated cyclic nucleotide formed during murine salmonellosis MH Zaki, S Fujii, T Okamoto, S Islam, S Khan, KA Ahmed, T Sawa, ... The Journal of Immunology 182 (6), 3746-3756, 2009 | 71 | 2009 |
Involvement of Salmonella enterica serovar Typhi RpoS in resistance to NO-mediated host defense against serovar Typhi infection MS Alam, MH Zaki, J Yoshitake, T Akuta, T Ezaki, T Akaike Microbial pathogenesis 40 (3), 116-125, 2006 | 44 | 2006 |
The AIM2 and NLRP3 inflammasomes trigger IL-1–mediated antitumor effects during radiation C Han, V Godfrey, Z Liu, Y Han, L Liu, H Peng, RR Weichselbaum, H Zaki, ... Science immunology 6 (59), eabc6998, 2021 | 42 | 2021 |
Nitrative stress through formation of 8-nitroguanosine: insights into microbial pathogenesis T Akuta, MH Zaki, J Yoshitake, T Okamoto, T Akaike Nitric Oxide 14 (2), 101-108, 2006 | 38 | 2006 |