| Structure of the human κ-opioid receptor in complex with JDTic H Wu, D Wacker, M Mileni, V Katritch, GW Han, E Vardy, W Liu, ... Nature 485 (7398), 327-332, 2012 | 1077 | 2012 |
| A new DREADD facilitates the multiplexed chemogenetic interrogation of behavior E Vardy, JE Robinson, C Li, RHJ Olsen, JF DiBerto, PM Giguere, ... Neuron 86 (4), 936-946, 2015 | 401 | 2015 |
| Structure of the nanobody-stabilized active state of the kappa opioid receptor T Che, S Majumdar, SA Zaidi, P Ondachi, JD McCorvy, S Wang, ... Cell 172 (1), 55-67. e15, 2018 | 356 | 2018 |
| Identification of the molecular mechanisms by which the diterpenoid salvinorin A binds to κ-opioid receptors F Yan, PD Mosier, RB Westkaemper, J Stewart, JK Zjawiony, ... Biochemistry 44 (24), 8643-8651, 2005 | 109 | 2005 |
| Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions PRB Joseph, PD Mosier, UR Desai, K Rajarathnam Biochemical Journal 472 (1), 121-133, 2015 | 104 | 2015 |
| QSAR/QSPR studies using probabilistic neural networks and generalized regression neural networks PD Mosier, PC Jurs Journal of chemical information and computer sciences 42 (6), 1460-1470, 2002 | 99 | 2002 |
| Finding a needle in a haystack: development of a combinatorial virtual screening approach for identifying high specificity heparin/heparan sulfate sequence (s) A Raghuraman, PD Mosier, UR Desai Journal of medicinal chemistry 49 (12), 3553-3562, 2006 | 83 | 2006 |
| Structure-based design, synthesis, and biochemical and pharmacological characterization of novel salvinorin A analogues as active state probes of the κ-opioid receptor F Yan, RV Bikbulatov, V Mocanu, N Dicheva, CE Parker, WC Wetsel, ... Biochemistry 48 (29), 6898-6908, 2009 | 79 | 2009 |
| Chemotype-selective modes of action of κ-opioid receptor agonists E Vardy, PD Mosier, KJ Frankowski, H Wu, V Katritch, RB Westkaemper, ... Journal of Biological Chemistry 288 (48), 34470-34483, 2013 | 68 | 2013 |
| Predicting the genotoxicity of thiophene derivatives from molecular structure PD Mosier, PC Jurs, LL Custer, SK Durham, GM Pearl Chemical research in toxicology 16 (6), 721-732, 2003 | 64 | 2003 |
| A Hexasaccharide Containing Rare 2‐O‐Sulfate‐Glucuronic Acid Residues Selectively Activates Heparin Cofactor II NV Sankaranarayanan, TR Strebel, RS Boothello, K Sheerin, ... Angewandte Chemie International Edition 56 (9), 2312-2317, 2017 | 61 | 2017 |
| Analogues of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1, 2, 3, 4-tetrahydronaphthalen-1-yl) propyl] piperazine (PB28) with added polar functionality and reduced … C Abate, M Niso, E Lacivita, PD Mosier, A Toscano, R Perrone Journal of medicinal chemistry 54 (4), 1022-1032, 2011 | 56 | 2011 |
| Gα-subunits differentially alter the conformation and agonist affinity of κ-opioid receptors F Yan, PD Mosier, RB Westkaemper, BL Roth Biochemistry 47 (6), 1567-1578, 2008 | 56 | 2008 |
| Prediction of peptide ion collision cross sections from topological molecular structure and amino acid parameters PD Mosier, AE Counterman, PC Jurs, DE Clemmer Analytical chemistry 74 (6), 1360-1370, 2002 | 56 | 2002 |
| Steric parameters, molecular modeling and hydropathic interaction analysis of the pharmacology of para‐substituted methcathinone analogues F Sakloth, R Kolanos, PD Mosier, JS Bonano, ML Banks, JS Partilla, ... British journal of pharmacology 172 (9), 2210-2218, 2015 | 52 | 2015 |
| On the specificity of heparin/heparan sulfate binding to proteins. Anion-binding sites on antithrombin and thrombin are fundamentally different PD Mosier, C Krishnasamy, GE Kellogg, UR Desai PLoS One 7 (11), e48632, 2012 | 52 | 2012 |
| Understanding Dermatan Sulfate− Heparin Cofactor II Interaction through Virtual Library Screening A Raghuraman, PD Mosier, UR Desai ACS Medicinal Chemistry Letters 1 (6), 281-285, 2010 | 45 | 2010 |
| Designing allosteric regulators of thrombin. Monosulfated benzofuran dimers selectively interact with Arg173 of exosite 2 to induce inhibition MH Abdel Aziz, PS Sidhu, A Liang, JY Kim, PD Mosier, Q Zhou, DH Farrell, ... Journal of medicinal chemistry 55 (15), 6888-6897, 2012 | 44 | 2012 |
| Designing allosteric regulators of thrombin. Monosulfated benzofuran dimers selectively interact with Arg173 of exosite 2 to induce inhibition MH Abdel Aziz, PS Sidhu, A Liang, JY Kim, PD Mosier, Q Zhou, DH Farrell, ... Journal of medicinal chemistry 55 (15), 6888-6897, 2012 | 44 | 2012 |
| Potential Modes of Interaction of 9-Aminomethyl-9,10-dihydroanthracene (AMDA) Derivatives with the 5-HT2A Receptor: A Ligand Structure-Affinity Relationship … SP Runyon, PD Mosier, BL Roth, RA Glennon, RB Westkaemper Journal of medicinal chemistry 51 (21), 6808-6828, 2008 | 42 | 2008 |
