|β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes|
AE Butler, J Janson, S Bonner-Weir, R Ritzel, RA Rizza, PC Butler
Diabetes 52 (1), 102-110, 2003
|Increased risk of type 2 diabetes in Alzheimer disease|
J Janson, T Laedtke, JE Parisi, P O’Brien, RC Petersen, PC Butler
Diabetes 53 (2), 474-481, 2004
|Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1–based therapies|
M Elashoff, AV Matveyenko, B Gier, R Elashoff, PC Butler
Gastroenterology 141 (1), 150-156, 2011
|Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers|
R Kayed, E Head, F Sarsoza, T Saing, CW Cotman, M Necula, L Margol, ...
Molecular neurodegeneration 2 (1), 1-11, 2007
|The mechanism of islet amyloid polypeptide toxicity is membrane disruption by intermediate-sized toxic amyloid particles.|
J Janson, RH Ashley, D Harrison, S McIntyre, PC Butler
Diabetes 48 (3), 491-498, 1999
|β-cell replication is the primary mechanism subserving the postnatal expansion of β-cell mass in humans|
JJ Meier, AE Butler, Y Saisho, T Monchamp, R Galasso, A Bhushan, ...
Diabetes 57 (6), 1584-1594, 2008
|Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis|
L Haataja, T Gurlo, CJ Huang, PC Butler
Endocrine reviews 29 (3), 303-316, 2008
|Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?|
JJ Meier, A Bhushan, AE Butler, RA Rizza, PC Butler
Diabetologia 48, 2221-2228, 2005
|Increased β-cell apoptosis prevents adaptive increase in β-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action …|
AE Butler, J Janson, WC Soeller, PC Butler
Diabetes 52 (9), 2304-2314, 2003
|Adaptive changes in pancreatic beta cell fractional area and beta cell turnover in human pregnancy|
AE Butler, L Cao-Minh, R Galasso, RA Rizza, A Corradin, C Cobelli, ...
Diabetologia 53, 2167-2176, 2010
|Pancreas volumes in humans from birth to age one hundred taking into account sex, obesity, and presence of type‐2 diabetes|
Y Saisho, AE Butler, JJ Meier, T Monchamp, M Allen‐Auerbach, RA Rizza, ...
Clinical anatomy 20 (8), 933-942, 2007
|Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing …|
AE Butler, M Campbell-Thompson, T Gurlo, DW Dawson, M Atkinson, ...
Diabetes 62 (7), 2595-2604, 2013
|High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress–mediated β-cell apoptosis, a characteristic of humans with type 2 but not type 1 …|
C Huang, C Lin, L Haataja, T Gurlo, AE Butler, RA Rizza, PC Butler
Diabetes 56 (8), 2016-2027, 2007
|Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide.|
J Janson, WC Soeller, PC Roche, RT Nelson, AJ Torchia, DK Kreutter, ...
Proceedings of the National Academy of Sciences 93 (14), 7283-7288, 1996
|Effects of meal ingestion on plasma amylin concentration in NIDDM and nondiabetic humans|
PC Butler, J Chou, WB Carter, YN Wang, BH Bu, D Chang, JK Chang, ...
Diabetes 39 (6), 752-756, 1990
|β-cell mass and turnover in humans: effects of obesity and aging|
Y Saisho, AE Butler, E Manesso, D Elashoff, RA Rizza, PC Butler
Diabetes care 36 (1), 111-117, 2013
|Assessment of β-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction, from intravenous and oral glucose tests|
C Cobelli, GM Toffolo, CD Man, M Campioni, P Denti, A Caumo, P Butler, ...
American Journal of Physiology-Endocrinology and Metabolism 293 (1), E1-E15, 2007
|The replication of β cells in normal physiology, in disease and for therapy|
PC Butler, JJ Meier, AE Butler, A Bhushan
Nature clinical practice Endocrinology & metabolism 3 (11), 758-768, 2007
|A critical analysis of the clinical use of incretin-based therapies: are the GLP-1 therapies safe?|
PC Butler, M Elashoff, R Elashoff, EAM Gale
Diabetes care 36 (7), 2118-2125, 2013
|Relationship between β‐cell mass and diabetes onset|
AV Matveyenko, PC Butler
Diabetes, Obesity and Metabolism 10, 23-31, 2008