|Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach|
R Chari, P Mali, M Moosburner, GM Church
Nature methods 12 (9), 823-826, 2015
|Comparison of Cas9 activators in multiple species|
A Chavez, M Tuttle, BW Pruitt, B Ewen-Campen, R Chari, ...
Nature methods 13 (7), 563-567, 2016
|Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers|
AW Briggs, X Rios, R Chari, L Yang, F Zhang, P Mali, GM Church
Nucleic acids research 40 (15), e117-e117, 2012
|Cas9 gRNA engineering for genome editing, activation and repression|
S Kiani, A Chavez, M Tuttle, RN Hall, R Chari, D Ter-Ovanesyan, J Qian, ...
Nature methods 12 (11), 1051-1054, 2015
|Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells|
J Soh, N Okumura, WW Lockwood, H Yamamoto, H Shigematsu, ...
PloS one 4 (10), e7464, 2009
|Whole-genome analysis and HLA genotyping of enteropathy-type T-cell lymphoma reveals 2 distinct lymphoma subtypes|
RJ Deleeuw, A Zettl, E Klinker, E Haralambieva, M Trottier, R Chari, Y Ge, ...
Gastroenterology 132 (5), 1902-1911, 2007
|High-resolution antibody dynamics of vaccine-induced immune responses|
U Laserson, F Vigneault, D Gadala-Maria, G Yaari, M Uduman, ...
Proceedings of the National Academy of Sciences 111 (13), 4928-4933, 2014
|TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer|
DT Starczynowski, WW Lockwood, S Deléhouzée, R Chari, J Wegrzyn, ...
The Journal of clinical investigation 121 (10), 4095-4105, 2011
|Recent advances in array comparative genomic hybridization technologies and their applications in human genetics|
WW Lockwood, R Chari, B Chi, WL Lam
European Journal of Human Genetics 14 (2), 139-148, 2006
|Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations|
DT Starczynowski, R Morin, A McPherson, J Lam, R Chari, J Wegrzyn, ...
Blood, The Journal of the American Society of Hematology 117 (2), 595-607, 2011
|Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells|
L Yang, D Grishin, G Wang, J Aach, CZ Zhang, R Chari, J Homsy, X Cai, ...
Nature communications 5 (1), 1-6, 2014
|DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers|
WW Lockwood, R Chari, BP Coe, L Girard, C Macaulay, S Lam, ...
Oncogene 27 (33), 4615-4624, 2008
|sgRNA Scorer 2.0: a species-independent model to predict CRISPR/Cas9 activity|
R Chari, NC Yeo, A Chavez, GM Church
ACS synthetic biology 6 (5), 902-904, 2017
|Translating cancer ‘omics’ to improved outcomes|
EA Vucic, KL Thu, K Robison, LA Rybaczyk, R Chari, CE Alvarez, WL Lam
Genome research 22 (2), 188-195, 2012
|A general strategy to construct small molecule biosensors in eukaryotes|
J Feng, BW Jester, CE Tinberg, DJ Mandell, MS Antunes, R Chari, ...
Elife 4, e10606, 2015
|Effect of active smoking on the human bronchial epithelium transcriptome|
R Chari, KM Lonergan, RT Ng, C MacAulay, WL Lam, S Lam
BMC genomics 8 (1), 1-13, 2007
|Integrative genomic analyses identify BRF2 as a novel lineage-specific oncogene in lung squamous cell carcinoma|
WW Lockwood, R Chari, BP Coe, KL Thu, C Garnis, CA Malloff, ...
PLoS Med 7 (7), e1000315, 2010
|DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways|
EA Vucic, R Chari, KL Thu, IM Wilson, AM Cotton, JY Kennett, M Zhang, ...
American journal of respiratory cell and molecular biology 50 (5), 912-922, 2014
|Long non-coding RNAs are expressed in oral mucosa and altered in oral premalignant lesions|
EA Gibb, KSS Enfield, GL Stewart, KM Lonergan, R Chari, RT Ng, ...
Oral oncology 47 (11), 1055-1061, 2011
|Differential disruption of cell cycle pathways in small cell and non-small cell lung cancer|
BP Coe, WW Lockwood, L Girard, R Chari, C Macaulay, S Lam, ...
British journal of cancer 94 (12), 1927-1935, 2006