Expression of multidrug resistance markers ABCB1 (MDR-1/P-gp) and ABCC1 (MRP-1) in renal cell carcinoma N Walsh, A Larkin, S Kennedy, L Connolly, J Ballot, W Ooi, G Gullo, ... BMC urology 9, 1-7, 2009 | 115 | 2009 |
RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation N Walsh, AM Larkin, N Swan, K Conlon, P Dowling, R McDermott, ... Cancer letters 306 (2), 180-189, 2011 | 104 | 2011 |
MDR1/P-glycoprotein and MRP-1 drug efflux pumps in pancreatic carcinoma L O'driscoll, N Walsh, A Larkin, J Ballot, WS Ooi, G Gullo, R O'CONNOR, ... Anticancer research 27 (4B), 2115-2120, 2007 | 92 | 2007 |
Identification of pancreatic cancer invasion-related proteins by proteomic analysis N Walsh, N O'Donovan, S Kennedy, M Henry, P Meleady, M Clynes, ... Proteome science 7, 1-14, 2009 | 79 | 2009 |
Challenges of drug resistance in the management of pancreatic cancer R Sheikh, N Walsh, M Clynes, R O’Connor, R McDermott Expert review of anticancer therapy 10 (10), 1647-1661, 2010 | 64 | 2010 |
Membrane transport proteins in human melanoma: associations with tumour aggressiveness and metastasis N Walsh, S Kennedy, AM Larkin, D Tryfonopoulos, AJ Eustace, ... British journal of cancer 102 (7), 1157-1162, 2010 | 48 | 2010 |
EGFR and HER2 inhibition in pancreatic cancer N Walsh, S Kennedy, AM Larkin, B Corkery, L O’Driscoll, M Clynes, ... Investigational new drugs 31, 558-566, 2013 | 41 | 2013 |
Modelling of pancreatic cancer biology: Transcriptomic signature for 3D PDX-derived organoids and primary cell line organoid development SR Nelson, C Zhang, S Roche, F O’Neill, N Swan, Y Luo, AM Larkin, ... Scientific Reports 10 (1), 2778, 2020 | 40 | 2020 |
Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL AJ Eustace, NT Conlon, MSJ McDermott, BC Browne, P O’Leary, ... Bmc Cancer 18, 1-14, 2018 | 33 | 2018 |
Alterations in integrin expression modulates invasion of pancreatic cancer cells N Walsh, M Clynes, J Crown, N O'Donovan Journal of Experimental & Clinical Cancer Research 28, 1-12, 2009 | 30 | 2009 |
Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells N Walsh, P Dowling, N O'Donovan, M Henry, P Meleady, M Clynes Journal of proteomics 71 (5), 561-571, 2008 | 25 | 2008 |
A two-gene prognostic classifier for early-stage lung squamous cell carcinoma in multiple large-scale and geographically diverse cohorts R Noro, T Ishigame, N Walsh, K Shiraishi, AI Robles, BM Ryan, ... Journal of Thoracic Oncology 12 (1), 65-76, 2017 | 24 | 2017 |
Membrane and membrane‐associated proteins involved in the aggressive phenotype displayed by highly invasive cancer cells P Dowling, N Walsh, M Clynes Proteomics 8 (19), 4054-4065, 2008 | 24 | 2008 |
Agnostic pathway/gene set analysis of genome-wide association data identifies associations for pancreatic cancer N Walsh, H Zhang, PL Hyland, Q Yang, E Mocci, M Zhang, EJ Childs, ... JNCI: Journal of the National Cancer Institute 111 (6), 557-567, 2019 | 23 | 2019 |
Kinase inhibitor screening identifies CDK4 as a potential therapeutic target for melanoma T Mahgoub, AJ Eustace, DM Collins, N Walsh, N O'Donovan, J Crown International Journal of Oncology 47 (3), 900-908, 2015 | 22 | 2015 |
The HSP90 inhibitor NVP-AUY922 inhibits growth of HER2 positive and trastuzumab-resistant breast cancer cells A Canonici, Z Qadir, NT Conlon, DM Collins, NA O’Brien, N Walsh, ... Investigational new drugs 36, 581-589, 2018 | 21 | 2018 |
Dasatinib treatment increases sensitivity to c-met inhibition in triple-negative breast cancer cells P Gaule, N Mukherjee, B Corkery, AJ Eustace, K Gately, S Roche, ... Cancers 11 (4), 548, 2019 | 20 | 2019 |
7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells D O’Sullivan, M Henry, H Joyce, N Walsh, EM Auley, P Dowling, N Swan, ... Tumor Biology 35, 6983-6997, 2014 | 18 | 2014 |
Impact of timing of trastuzumab initiation on long-term outcome of patients with early-stage HER2-positive breast cancer: the “one thousand HER2 patients” project G Gullo, N Walsh, D Fennelly, R Bose, J Walshe, D Tryfonopoulos, ... British Journal of Cancer 119 (3), 374-380, 2018 | 16 | 2018 |
Os (II)-bridged polyarginine conjugates: the additive effects of peptides in promoting or preventing permeation in cells and multicellular tumor spheroids KS Gkika, S Noorani, N Walsh, TE Keyes Inorganic Chemistry 60 (11), 8123-8134, 2021 | 11 | 2021 |