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Patrick Raynal
Patrick Raynal
INSERM Research director (DR2), CERPPS (UT2), TMBI (Univ. Toulouse)
Verified email at inserm.fr
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Cited by
Year
Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium-and phospholipid-binding proteins
P Raynal, HB Pollard
Biochimica et Biophysica Acta (BBA)-Reviews on Biomembranes 1197 (1), 63-93, 1994
13591994
The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway
M Dance, A Montagner, JP Salles, A Yart, P Raynal
Cellular signalling 20 (3), 453-459, 2008
3492008
A novel role for Gab1 and SHP2 in epidermal growth factor-induced Ras activation
A Montagner, A Yart, M Dance, B Perret, JP Salles, P Raynal
Journal of Biological Chemistry 280 (7), 5350-5360, 2005
2162005
A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor
A Yart, M Laffargue, P Mayeux, S Chretien, C Peres, N Tonks, S Roche, ...
Journal of Biological Chemistry 276 (12), 8856-8864, 2001
1882001
A function for phosphatidylinositol 3-kinase β (p85α-p110β) in fibroblasts during mitogenesis: requirement for insulin-and lysophosphatidic acid-mediated signal transduction
S Roche, J Downward, P Raynal, SA Courtneidge
Molecular and cellular biology 18 (12), 7119-7129, 1998
1771998
Reduced phosphatase activity of SHP‐2 in LEOPARD syndrome: Consequences for PI3K binding on Gab1
N Hanna, A Montagner, WH Lee, M Miteva, M Vidal, M Vidaud, B Parfait, ...
FEBS letters 580 (10), 2477-2482, 2006
1282006
Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature
ADR Serra-Nédélec, T Edouard, K Tréguer, M Tajan, T Araki, M Dance, ...
Proceedings of the National Academy of Sciences 109 (11), 4257-4262, 2012
1202012
Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature
ADR Serra-Nédélec, T Edouard, K Tréguer, M Tajan, T Araki, M Dance, ...
Proceedings of the National Academy of Sciences 109 (11), 4257-4262, 2012
1202012
Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature
ADR Serra-Nédélec, T Edouard, K Tréguer, M Tajan, T Araki, M Dance, ...
Proceedings of the National Academy of Sciences 109 (11), 4257-4262, 2012
1202012
A function for phosphoinositide 3-kinase β lipid products in coupling βγ to Ras activation in response to lysophosphatidic acid
A Yart, S Roche, R Wetzker, M Laffargue, N Tonks, P Mayeux, H Chap, ...
Journal of Biological Chemistry 277 (24), 21167-21178, 2002
1162002
Lipid products of phosphoinositide 3-kinase interact with Rac1 GTPase and stimulate GDP dissociation
K Missy, V Van Poucke, P Raynal, C Viala, G Mauco, M Plantavid, H Chap, ...
Journal of Biological Chemistry 273 (46), 30279-30286, 1998
1151998
An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid
M Laffargue, P Raynal, A Yart, C Peres, R Wetzker, S Roche, B Payrastre, ...
Journal of Biological Chemistry 274 (46), 32835-32841, 1999
1061999
Phosphoinositide 3-OH kinase p85α and p110β are essential for androgen receptor transactivation and tumor progression in prostate cancers
Q Zhu, H Youn, J Tang, O Tawfik, K Dennis, PF Terranova, J Du, P Raynal, ...
Oncogene 27 (33), 4569-4579, 2008
1042008
Phosphoinositide 3-kinases in lysophosphatidic acid signaling: regulation and cross-talk with the Ras/mitogen-activated protein kinase pathway
A Yart, H Chap, P Raynal
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2002
1032002
Functional Effects of PTPN11 (SHP2) Mutations Causing LEOPARD Syndrome on Epidermal Growth Factor-Induced Phosphoinositide 3-Kinase/AKT/Glycogen …
T Edouard, JP Combier, A Nédélec, S Bel-Vialar, M Métrich, ...
Molecular and Cellular Biology 30 (10), 2498-2507, 2010
1022010
Effect of Dexamethasone on Prostaglandin Synthesis and on Lipocortin Status in Human Endothelial Cells: Inhibition of prostaglandin I2 synthesis occurring without alteration of …
F Hullin, P Raynal, JMF Ragab-Thomas, J Fauvel, H Chap
Journal of Biological Chemistry 264 (6), 3506-3513, 1989
1011989
The adaptor protein Gab1 couples the stimulation of vascular endothelial growth factor receptor-2 to the activation of phosphoinositide 3-kinase
M Dance, A Montagner, A Yart, B Masri, Y Audigier, B Perret, JP Salles, ...
Journal of Biological Chemistry 281 (32), 23285-23295, 2006
832006
Myeloid Dysregulation in a Human Induced Pluripotent Stem Cell Model of PTPN11-Associated Juvenile Myelomonocytic Leukemia
S Mulero-Navarro, A Sevilla, AC Roman, DF Lee, SL D’Souza, S Pardo, ...
Cell reports 13 (3), 504-515, 2015
742015
LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesity
M Tajan, A Batut, T Cadoudal, S Deleruyelle, S Le Gonidec, ...
Proceedings of the National Academy of Sciences 111 (42), E4494-E4503, 2014
632014
Modulation of phosphoinositide 3-kinase activation by cholesterol level suggests a novel positive role for lipid rafts in lysophosphatidic acid signalling
C Peres, A Yart, B Perret, JP Salles, P Raynal
FEBS letters 534 (1-3), 164-168, 2003
632003
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