Annexins: the problem of assessing the biological role for a gene family of multifunctional calcium-and phospholipid-binding proteins P Raynal, HB Pollard Biochimica et Biophysica Acta (BBA)-Reviews on Biomembranes 1197 (1), 63-93, 1994 | 1381 | 1994 |
The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway M Dance, A Montagner, JP Salles, A Yart, P Raynal Cellular signalling 20 (3), 453-459, 2008 | 397 | 2008 |
A novel role for Gab1 and SHP2 in epidermal growth factor-induced Ras activation A Montagner, A Yart, M Dance, B Perret, JP Salles, P Raynal Journal of Biological Chemistry 280 (7), 5350-5360, 2005 | 244 | 2005 |
A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor A Yart, M Laffargue, P Mayeux, S Chretien, C Peres, N Tonks, S Roche, ... Journal of Biological Chemistry 276 (12), 8856-8864, 2001 | 195 | 2001 |
A function for phosphatidylinositol 3-kinase β (p85α-p110β) in fibroblasts during mitogenesis: requirement for insulin-and lysophosphatidic acid-mediated signal transduction S Roche, J Downward, P Raynal, SA Courtneidge Molecular and cellular biology 18 (12), 7119-7129, 1998 | 175 | 1998 |
Reduced phosphatase activity of SHP‐2 in LEOPARD syndrome: Consequences for PI3K binding on Gab1 N Hanna, A Montagner, WH Lee, M Miteva, M Vidal, M Vidaud, B Parfait, ... FEBS letters 580 (10), 2477-2482, 2006 | 134 | 2006 |
Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature ADR Serra-Nédélec, T Edouard, K Tréguer, M Tajan, T Araki, M Dance, ... Proceedings of the National Academy of Sciences 109 (11), 4257-4262, 2012 | 129 | 2012 |
Lipid products of phosphoinositide 3-kinase interact with Rac1 GTPase and stimulate GDP dissociation K Missy, V Van Poucke, P Raynal, C Viala, G Mauco, M Plantavid, H Chap, ... Journal of Biological Chemistry 273 (46), 30279-30286, 1998 | 120 | 1998 |
A function for phosphoinositide 3-kinase β lipid products in coupling βγ to Ras activation in response to lysophosphatidic acid A Yart, S Roche, R Wetzker, M Laffargue, N Tonks, P Mayeux, H Chap, ... Journal of Biological Chemistry 277 (24), 21167-21178, 2002 | 118 | 2002 |
An epidermal growth factor receptor/Gab1 signaling pathway is required for activation of phosphoinositide 3-kinase by lysophosphatidic acid M Laffargue, P Raynal, A Yart, C Peres, R Wetzker, S Roche, B Payrastre, ... Journal of Biological Chemistry 274 (46), 32835-32841, 1999 | 117 | 1999 |
Functional effects of PTPN11 (SHP2) mutations causing LEOPARD syndrome on epidermal growth factor-induced phosphoinositide 3-kinase/AKT/glycogen synthase kinase 3β signaling T Edouard, JP Combier, A Nédélec, S Bel-Vialar, M Métrich, ... Molecular and Cellular Biology, 2010 | 115 | 2010 |
Phosphoinositide 3-OH kinase p85α and p110β are essential for androgen receptor transactivation and tumor progression in prostate cancers Q Zhu, H Youn, J Tang, O Tawfik, K Dennis, PF Terranova, J Du, P Raynal, ... Oncogene 27 (33), 4569-4579, 2008 | 107 | 2008 |
Effect of Dexamethasone on Prostaglandin Synthesis and on Lipocortin Status in Human Endothelial Cells: Inhibition of prostaglandin I2 synthesis occurring without alteration of … F Hullin, P Raynal, JMF Ragab-Thomas, J Fauvel, H Chap Journal of Biological Chemistry 264 (6), 3506-3513, 1989 | 107 | 1989 |
Phosphoinositide 3-kinases in lysophosphatidic acid signaling: regulation and cross-talk with the Ras/mitogen-activated protein kinase pathway A Yart, H Chap, P Raynal Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2002 | 103 | 2002 |
Myeloid dysregulation in a human induced pluripotent stem cell model of PTPN11-associated juvenile myelomonocytic leukemia S Mulero-Navarro, A Sevilla, AC Roman, DF Lee, SL D’Souza, S Pardo, ... Cell reports 13 (3), 504-515, 2015 | 88 | 2015 |
The adaptor protein Gab1 couples the stimulation of vascular endothelial growth factor receptor-2 to the activation of phosphoinositide 3-kinase M Dance, A Montagner, A Yart, B Masri, Y Audigier, B Perret, JP Salles, ... Journal of Biological Chemistry 281 (32), 23285-23295, 2006 | 84 | 2006 |
LEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesity M Tajan, A Batut, T Cadoudal, S Deleruyelle, S Le Gonidec, ... Proceedings of the National Academy of Sciences 111 (42), E4494-E4503, 2014 | 69 | 2014 |
Modulation of phosphoinositide 3-kinase activation by cholesterol level suggests a novel positive role for lipid rafts in lysophosphatidic acid signalling C Peres, A Yart, B Perret, JP Salles, P Raynal FEBS letters 534 (1-3), 164-168, 2003 | 66 | 2003 |
Signal strength dictates phosphoinositide 3-kinase contribution to Ras/extracellular signal-regulated kinase 1 and 2 activation via differential Gab1/Shp2 recruitment … C Sampaio, M Dance, A Montagner, T Edouard, N Malet, B Perret, A Yart, ... Molecular and cellular biology, 2008 | 63 | 2008 |
Annexin 5 as a potential regulator of annexin 1 phosphorylation by protein kinase C. In vitro inhibition compared with quantitative data on annexin distribution in … P Raynal, F Hullin, JMF Ragab-Thomas, J Fauvel, H Chap Biochemical Journal 292 (3), 759-765, 1993 | 62 | 1993 |