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Kevin Shannon
Kevin Shannon
Professor of Pediatrics, UCSF
Geverifieerd e-mailadres voor ucsf.edu - Homepage
Titel
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Jaar
Hyperactive Ras in developmental disorders and cancer
S Schubbert, K Shannon, G Bollag
Nature Reviews Cancer 7 (4), 295-308, 2007
19342007
Functional genomic landscape of acute myeloid leukaemia
JW Tyner, CE Tognon, D Bottomly, B Wilmot, SE Kurtz, SL Savage, ...
Nature 562 (7728), 526-531, 2018
10302018
Germline KRAS mutations cause Noonan syndrome
S Schubbert, M Zenker, SL Rowe, S Böll, C Klein, G Bollag, ...
Nature genetics 38 (3), 331-336, 2006
8462006
The rate of telomere sequence loss in human leukocytes varies with age
RW Frenck Jr, EH Blackburn, KM Shannon
Proceedings of the National Academy of Sciences 95 (10), 5607-5610, 1998
7671998
Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon
KM Haigis, KR Kendall, Y Wang, A Cheung, MC Haigis, JN Glickman, ...
Nature genetics 40 (5), 600-608, 2008
6922008
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells
G Bollag, DW Clapp, S Shih, F Adler, YY Zhang, P Thompson, BJ Lange, ...
Nature genetics 12 (2), 144-148, 1996
6911996
Loss of the normal NF1 allele from the bone marrow of children with type 1 neurofibromatosis and malignant myeloid disorders
KM Shannon, P O'Connell, GA Martin, D Paderanga, K Olson, P Dinndorf, ...
New England Journal of Medicine 330 (9), 597-601, 1994
5101994
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis
ML Loh, S Vattikuti, S Schubbert, MG Reynolds, E Carlson, KH Lieuw, ...
Blood 103 (6), 2325-2331, 2004
4902004
Recombinant human erythropoietin stimulates erythropoiesis and reduces erythrocyte transfusions in very low birth weight preterm infants
KM Shannon, JF Keith III, WC Mentzer, RA Ehrenkranz, MS Brown, ...
Pediatrics 95 (1), 1-8, 1995
4111995
Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder
BS Braun, DA Tuveson, N Kong, DT Le, SC Kogan, J Rozmus, ...
Proceedings of the National Academy of Sciences 101 (2), 597-602, 2004
3542004
Mutations in CBL occur frequently in juvenile myelomonocytic leukemia
ML Loh, DS Sakai, C Flotho, M Kang, M Fliegauf, S Archambeault, ...
Blood, The Journal of the American Society of Hematology 114 (9), 1859-1863, 2009
3412009
MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia
C Chen, Y Liu, AR Rappaport, T Kitzing, N Schultz, Z Zhao, AS Shroff, ...
Cancer cell 25 (5), 652-665, 2014
3352014
Outcomes in CCG-2961, a children's oncology group phase 3 trial for untreated pediatric acute myeloid leukemia: a report from the children's oncology group
BJ Lange, FO Smith, J Feusner, DR Barnard, P Dinndorf, S Feig, ...
Blood, The Journal of the American Society of Hematology 111 (3), 1044-1053, 2008
3312008
Homozygous inactivation of the NF1 gene in bone marrow cells from children with neurofibromatosis type 1 and malignant myeloid disorders
L Side, B Taylor, M Cayouette, E Conner, P Thompson, M Luce, ...
New England Journal of Medicine 336 (24), 1713-1720, 1997
3261997
GTPase activating proteins: critical regulators of intracellular signaling
S Donovan, KM Shannon, G Bollag
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1602 (1), 23-45, 2002
3092002
Childhood monosomy 7: epidemiology, biology, and mechanistic implications
S Luna-Fineman, KM Shannon, BJ Lange
2951995
Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates
N Kotecha, NJ Flores, JM Irish, EF Simonds, DS Sakai, S Archambeault, ...
Cancer cell 14 (4), 335-343, 2008
2812008
Myelodysplastic and myeloproliferative disorders of childhood: a study of 167 patients
S Luna-Fineman, KM Shannon, SK Atwater, J Davis, M Masterson, ...
Blood, The Journal of the American Society of Hematology 93 (2), 459-466, 1999
2641999
Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells
E Kim, P Ambroziak, JC Otto, B Taylor, M Ashby, K Shannon, PJ Casey, ...
Journal of Biological Chemistry 274 (13), 8383-8390, 1999
2511999
Mutations of the NF1 Gene in Children With Juvenile Myelomonocytic Leukemia Without Clinical Evidence of Neurofibromatosis, Type 1
LE Side, PD Emanuel, B Taylor, J Franklin, P Thompson, RP Castleberry, ...
Blood, The Journal of the American Society of Hematology 92 (1), 267-272, 1998
2371998
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Artikelen 1–20