Kynan Lawlor
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Evaluation of variability in human kidney organoids
B Phipson, XE Pei, AN Combes, TA Forbes, SE Howden, L Zappia, ...
Nature methods 16 (1), 79-87, 2019
952019
Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype and reveal underlying pathogenetic mechanisms
TA Forbes, SE Howden, K Lawlor, B Phipson, J Maksimovic, L Hale, ...
The American Journal of Human Genetics 102 (5), 816-831, 2018
882018
3D organoid-derived human glomeruli for personalised podocyte disease modelling and drug screening
LJ Hale, SE Howden, B Phipson, A Lonsdale, XE Pei, I Ghobrial, ...
Nature communications 9 (1), 1-17, 2018
782018
Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk
AN Combes, B Phipson, KT Lawlor, A Dorison, R Patrick, L Zappia, ...
Development 146 (12), dev178673, 2019
582019
Double-stranded RNA is pathogenic in Drosophila models of expanded repeat neurodegenerative diseases
KT Lawlor, LV O'Keefe, SE Samaraweera, CL van Eyk, CJ McLeod, ...
Human Molecular Genetics 20 (19), 3757-3768, 2011
552011
Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells
SV Kumar, PX Er, KT Lawlor, A Motazedian, M Scurr, I Ghobrial, ...
Development 146 (5), dev172361, 2019
372019
Dermal contributions to human interfollicular epidermal architecture and self-renewal
KT Lawlor, P Kaur
International journal of molecular sciences 16 (12), 28098-28107, 2015
372015
Perturbation of the Akt/Gsk3-β signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs
CL Van Eyk, LV O'Keefe, KT Lawlor, SE Samaraweera, CJ McLeod, ...
Human molecular genetics 20 (14), 2783-2794, 2011
332011
Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation
KT Lawlor, JM Vanslambrouck, JW Higgins, A Chambon, K Bishard, ...
Nature materials 20 (2), 260-271, 2021
252021
Nephron progenitor commitment is a stochastic process influenced by cell migration
KT Lawlor, L Zappia, J Lefevre, JS Park, NA Hamilton, A Oshlack, ...
Elife 8, e41156, 2019
242019
Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number
AN Combes, S Wilson, B Phipson, BB Binnie, A Ju, KT Lawlor, C Cebrian, ...
Kidney international 93 (3), 589-598, 2018
212018
Bioprinted pluripotent stem cell-derived kidney organoids provide opportunities for high content screening
JW Higgins, A Chambon, K Bishard, A Hartung, D Arndt, J Brugnano, ...
bioRxiv, 505396, 2018
142018
High throughput single cell RNA-seq of developing mouse kidney and human kidney organoids reveals a roadmap for recreating the kidney
AN Combes, B Phipson, L Zappia, KT Lawlor, PX Er, A Oshlack, MH Little
BioRXIV, 235499, 2017
132017
Pericytes promote skin regeneration by inducing epidermal cell polarity and planar cell divisions
L Zhuang, KT Lawlor, H Schlueter, Z Pieterse, Y Yu, P Kaur
Life science alliance 1 (4), 2018
122018
Ubiquitous expression of CUG or CAG trinucleotide repeat RNA causes common morphological defects in a Drosophila model of RNA-mediated pathology
KT Lawlor, LV O’Keefe, SE Samaraweera, CL Van Eyk, RI Richards
PLoS One 7 (6), e38516, 2012
112012
Drosophila Dachsous and Fat polarize actin-based protrusions over a restricted domain of the embryonic denticle field
KT Lawlor, DC Ly, S DiNardo
Developmental biology 383 (2), 285-294, 2013
102013
Correction: Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk (doi: 10.1242/dev. 178673)
AN Combes, B Phipson, KT Lawlor, A Dorison, R Patrick, L Zappia, ...
Development 146 (13), dev182162, 2019
82019
Modeling and Analysis of Repeat RNA Toxicity in Drosophila
SE Samaraweera, LV O’Keefe, CL van Eyk, KT Lawlor, DT Humphreys, ...
Tandem Repeats in Genes, Proteins, and Disease, 173-192, 2013
32013
Recreating, expanding and using nephron progenitor populations
MH Little, KT Lawlor
Nature Reviews Nephrology 16 (2), 75-76, 2020
12020
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Artikelen 1–19