Global epidemiology of drug resistance after failure of WHO recommended first-line regimens for adult HIV-1 infection: a multicentre retrospective cohort study J Gregson, M Tang, N Ndembi, RL Hamers, SY Rhee, VC Marconi, ... The Lancet infectious diseases 16 (5), 565-575, 2016 | 299 | 2016 |
HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics AB Abecasis, AMJ Wensing, D Paraskevis, J Vercauteren, K Theys, ... Retrovirology 10, 1-13, 2013 | 187 | 2013 |
An integrated map of HIV genome-wide variation from a population perspective G Li, S Piampongsant, NR Faria, A Voet, AC Pineda-Peña, R Khouri, ... Retrovirology 12, 1-18, 2015 | 161 | 2015 |
Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research F Hufsky, K Lamkiewicz, A Almeida, A Aouacheria, C Arighi, A Bateman, ... Briefings in bioinformatics 22 (2), 642-663, 2021 | 153 | 2021 |
A computational method for the identification of Dengue, Zika and Chikungunya virus species and genotypes V Fonseca, PJK Libin, K Theys, NR Faria, MRT Nunes, MI Restovic, ... PLoS neglected tropical diseases 13 (5), e0007231, 2019 | 87 | 2019 |
Genetic diversity and selective pressure in hepatitis C virus genotypes 1–6: significance for direct-acting antiviral treatment and drug resistance L Cuypers, G Li, P Libin, S Piampongsant, AM Vandamme, K Theys Viruses 7 (9), 5018-5039, 2015 | 86 | 2015 |
CRF19_cpx is an evolutionary fit HIV-1 variant strongly associated with rapid progression to AIDS in Cuba V Kouri, R Khouri, Y Alemán, Y Abrahantes, J Vercauteren, ... EBioMedicine 2 (3), 244-254, 2015 | 80 | 2015 |
Functional conservation of HIV-1 Gag: implications for rational drug design G Li, J Verheyen, SY Rhee, A Voet, AM Vandamme, K Theys Retrovirology 10, 1-11, 2013 | 77 | 2013 |
VIRULIGN: fast codon-correct alignment and annotation of viral genomes PJK Libin, K Deforche, AB Abecasis, K Theys Bioinformatics 35 (10), 1763-1765, 2019 | 66 | 2019 |
The incidence of multidrug and full class resistance in HIV-1 infected patients is decreasing over time (2001–2006) in Portugal J Vercauteren, K Deforche, K Theys, M Debruyne, LM Duque, S Peres, ... Retrovirology 5, 1-8, 2008 | 65 | 2008 |
The impact of HIV-1 within-host evolution on transmission dynamics K Theys, P Libin, AC Pineda-Pena, A Nowe, AM Vandamme, AB Abecasis Current opinion in virology 28, 92-101, 2018 | 57 | 2018 |
HIV-1 genotypic drug resistance testing: digging deep, reaching wide? K Van Laethem, K Theys, AM Vandamme Current opinion in virology 14, 16-23, 2015 | 54 | 2015 |
HIV-1 subtype is an independent predictor of reverse transcriptase mutation K65R in HIV-1 patients treated with combination antiretroviral therapy including tenofovir K Theys, J Vercauteren, J Snoeck, M Zazzi, RJ Camacho, C Torti, ... Antimicrobial agents and chemotherapy 57 (2), 1053-1056, 2013 | 50 | 2013 |
Covering all bases in HIV research: unveiling a hidden world of viral evolution. B Vrancken, S Lequime, K Theys, P Lemey AIDS reviews 12 (2), 89-102, 2010 | 38 | 2010 |
Within-patient mutation frequencies reveal fitness costs of CpG dinucleotides and drastic amino acid changes in HIV K Theys, AF Feder, M Gelbart, M Hartl, A Stern, PS Pennings PLoS genetics 14 (6), e1007420, 2018 | 36* | 2018 |
Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients K Theys, K Deforche, J Vercauteren, P Libin, DAMC van de Vijver, J Albert, ... Retrovirology 9, 1-13, 2012 | 33 | 2012 |
RegaDB: community-driven data management and analysis for infectious diseases P Libin, G Beheydt, K Deforche, S Imbrechts, F Ferreira, K Van Laethem, ... Bioinformatics 29 (11), 1477-1480, 2013 | 32 | 2013 |
Modelled in vivo HIV Fitness under drug Selective Pressure and Estimated Genetic Barrier Towards Resistance are Predictive for Virological Response EuroSIDA Study Group Antiviral Therapy 13 (3), 399-408, 2008 | 32 | 2008 |
SANTA-SIM: simulating viral sequence evolution dynamics under selection and recombination A Jariani, C Warth, K Deforche, P Libin, AJ Drummond, A Rambaut, ... Virus evolution 5 (1), vez003, 2019 | 31 | 2019 |
Bayesian best-arm identification for selecting influenza mitigation strategies PJK Libin, T Verstraeten, DM Roijers, J Grujic, K Theys, P Lemey, A Nowé Machine Learning and Knowledge Discovery in Databases: European Conference …, 2019 | 27 | 2019 |