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Gleb Kichaev
Gleb Kichaev
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Year
Leveraging polygenic functional enrichment to improve GWAS power
G Kichaev, G Bhatia, PR Loh, S Gazal, K Burch, MK Freund, A Schoech, ...
The American Journal of Human Genetics 104 (1), 65-75, 2019
7972019
Mixed-model association for biobank-scale datasets
PR Loh, G Kichaev, S Gazal, AP Schoech, AL Price
Nature genetics 50 (7), 906-908, 2018
5932018
Integrating functional data to prioritize causal variants in statistical fine-mapping studies
G Kichaev, WY Yang, S Lindstrom, F Hormozdiari, E Eskin, AL Price, ...
PLoS genetics 10 (10), e1004722, 2014
5182014
Contrasting the Genetic Architecture of 30 Complex Traits from Summary Association Data
H Shi, G Kichaev, B Pasaniuc
American Journal of Human Genetics 99 (1), 139-53, 2016
3922016
Probabilistic fine-mapping of transcriptome-wide association studies
N Mancuso, MK Freund, R Johnson, H Shi, G Kichaev, A Gusev, ...
Nature genetics 51 (4), 675-682, 2019
2832019
Integrating gene expression with summary association statistics to identify genes associated with 30 complex traits
N Mancuso, H Shi, P Goddard, G Kichaev, A Gusev, B Pasaniuc
The American Journal of Human Genetics 100 (3), 473-487, 2017
2572017
Leveraging functional-annotation data in trans-ethnic fine-mapping studies
G Kichaev, B Pasaniuc
The American Journal of Human Genetics 97 (2), 260-271, 2015
1932015
Improved methods for multi-trait fine mapping of pleiotropic risk loci
G Kichaev, M Roytman, R Johnson, E Eskin, S Lindstroem, P Kraft, ...
Bioinformatics 33 (2), 248-255, 2017
1252017
Enhanced Delivery and Potency of Self-Amplifying mRNA Vaccines by Electroporation in Situ
Y Cu, KE Broderick, K Banerjee, J Hickman, G Otten, S Barnett, G Kichaev, ...
Vaccines 1 (3), 367-383, 2013
1052013
Identification of causal genes for complex traits
F Hormozdiari, G Kichaev, WY Yang, B Pasaniuc, E Eskin
Bioinformatics 31 (12), i206-i213, 2015
1032015
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function
AB Wyss, T Sofer, MK Lee, N Terzikhan, JN Nguyen, L Lahousse, ...
Nature communications 9 (1), 2976, 2018
942018
Phenotype-specific enrichment of Mendelian disorder genes near GWAS regions across 62 complex traits
MK Freund, KS Burch, H Shi, N Mancuso, G Kichaev, KM Garske, DZ Pan, ...
The American Journal of Human Genetics 103 (4), 535-552, 2018
882018
Widespread allelic heterogeneity in complex traits
F Hormozdiari, A Zhu, G Kichaev, CJT Ju, AV Segrč, JWJ Joo, H Won, ...
The American Journal of Human Genetics 100 (5), 789-802, 2017
812017
Localizing components of shared transethnic genetic architecture of complex traits from GWAS summary data
H Shi, KS Burch, R Johnson, MK Freund, G Kichaev, N Mancuso, ...
The American Journal of Human Genetics 106 (6), 805-817, 2020
702020
Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation
A Gusev, H Shi, G Kichaev, M Pomerantz, F Li, HW Long, SA Ingles, ...
Nature communications 7 (1), 10979, 2016
542016
Optimization of electroporation-enhanced intradermal delivery of DNA vaccine using a minimally invasive surface device
F Lin, X Shen, G Kichaev, JM Mendoza, M Yang, P Armendi, J Yan, ...
Human Gene Therapy, Part B: Methods 23 (3), 157-168, 2012
542012
Optimized in vivo transfer of small interfering RNA targeting dermal tissue using in vivo surface electroporation
KE Broderick, A Chan, F Lin, X Shen, G Kichaev, AS Khan, J Aubin, ...
Molecular Therapy-Nucleic Acids 1, 2012
422012
Electroporation mediated DNA vaccination directly to a mucosal surface results in improved immune responses
G Kichaev, JM Mendoza, D Amante, TRF Smith, JR McCoy, NY Sardesai, ...
Human vaccines & immunotherapeutics 9 (10), 2041-2048, 2013
352013
Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci
N Zubair, M Graff, J Luis Ambite, WS Bush, G Kichaev, Y Lu, ...
Human molecular genetics 25 (24), 5500-5512, 2016
332016
Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability
B van de Geijn, H Finucane, S Gazal, F Hormozdiari, T Amariuta, X Liu, ...
Human molecular genetics 29 (7), 1057-1067, 2020
172020
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