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James Doroghazi
James Doroghazi
Computational Life Science Portfolio, Bayer CropScience
Geverifieerd e-mailadres voor bayer.com
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A roadmap for natural product discovery based on large-scale genomics and metabolomics
JR Doroghazi, JC Albright, AW Goering, KS Ju, RR Haines, KA Tchalukov, ...
Nature chemical biology 10 (11), 963-968, 2014
5032014
Comparative genomics of actinomycetes with a focus on natural product biosynthetic genes
JR Doroghazi, WW Metcalf
BMC genomics 14, 1-13, 2013
2422013
Curcumin inhibits herpes simplex virus immediate-early gene expression by a mechanism independent of p300/CBP histone acetyltransferase activity
SB Kutluay, J Doroghazi, ME Roemer, SJ Triezenberg
Virology 373 (2), 239-247, 2008
2282008
Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes
KS Ju, J Gao, JR Doroghazi, KKA Wang, CJ Thibodeaux, S Li, E Metzger, ...
Proceedings of the National Academy of Sciences 112 (39), 12175-12180, 2015
2022015
Diversity and abundance of phosphonate biosynthetic genes in nature
X Yu, JR Doroghazi, SC Janga, JK Zhang, B Circello, BM Griffin, ...
Proceedings of the National Academy of Sciences 110 (51), 20759-20764, 2013
1612013
Phylogenetic relationships in the family Streptomycetaceae using multi-locus sequence analysis
DP Labeda, CA Dunlap, X Rong, Y Huang, JR Doroghazi, KS Ju, ...
Antonie Van Leeuwenhoek 110, 563-583, 2017
1272017
Widespread homologous recombination within and between Streptomyces species
JR Doroghazi, DH Buckley
The ISME journal 4 (9), 1136-1143, 2010
1262010
Metabologenomics: correlation of microbial gene clusters with metabolites drives discovery of a nonribosomal peptide with an unusual amino acid monomer
AW Goering, RA McClure, JR Doroghazi, JC Albright, NA Haverland, ...
ACS central science 2 (2), 99-108, 2016
1252016
A Latitudinal Diversity Gradient in Terrestrial Bacteria of the Genus Streptomyces
CP Andam, JR Doroghazi, AN Campbell, PJ Kelly, MJ Choudoir, ...
MBio 7 (2), 10.1128/mbio. 02200-15, 2016
1152016
Expanded natural product diversity revealed by analysis of lanthipeptide-like gene clusters in actinobacteria
Q Zhang, JR Doroghazi, X Zhao, MC Walker, WA van der Donk
Applied and environmental microbiology 81 (13), 4339-4350, 2015
892015
The genomic landscape of ribosomal peptides containing thiazole and oxazole heterocycles
CL Cox, JR Doroghazi, DA Mitchell
BMC genomics 16, 1-16, 2015
812015
Taxonomic evaluation of Streptomyces albus and related species using multilocus sequence analysis and proposals to emend the description of Streptomyces albus and …
DP Labeda, JR Doroghazi, KS Ju, WW Metcalf
International journal of systematic and evolutionary microbiology 64 (Pt_3 …, 2014
812014
Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways
KS Ju, JR Doroghazi, WW Metcalf
Journal of Industrial Microbiology and Biotechnology 41 (2), 345-356, 2014
712014
Nucleophilic 1, 4-additions for natural product discovery
CL Cox, JI Tietz, K Sokolowski, JO Melby, JR Doroghazi, DA Mitchell
ACS chemical biology 9 (9), 2014-2022, 2014
682014
Use of a phosphonate methyltransferase in the identification of the fosfazinomycin biosynthetic gene cluster
J Gao, KS Ju, X Yu, JE Velásquez, S Mukherjee, J Lee, C Zhao, BS Evans, ...
Angewandte Chemie 126 (5), 1358-1361, 2014
562014
Plantazolicin Is an Ultranarrow-Spectrum Antibiotic That Targets the Bacillus anthracis Membrane
KJ Molohon, PMB Saint-Vincent, S Park, JR Doroghazi, T Maxson, ...
ACS infectious diseases 2 (3), 207-220, 2015
552015
A proteomic survey of nonribosomal peptide and polyketide biosynthesis in actinobacteria
Y Chen, I Ntai, KS Ju, M Unger, L Zamdborg, SJ Robinson, JR Doroghazi, ...
Journal of proteome research 11 (1), 85-94, 2012
512012
Strain-specific proteogenomics accelerates the discovery of natural products via their biosynthetic pathways
JC Albright, AW Goering, JR Doroghazi, WW Metcalf, NL Kelleher
Journal of Industrial Microbiology and Biotechnology 41 (2), 451-459, 2014
472014
Intraspecies comparison of Streptomyces pratensis genomes reveals high levels of recombination and gene conservation between strains of disparate geographic …
JR Doroghazi, DH Buckley
BMC genomics 15, 1-14, 2014
442014
Latitude delineates patterns of biogeography in terrestrial Streptomyces
MJ Choudoir, JR Doroghazi, DH Buckley
Environmental microbiology 18 (12), 4931-4945, 2016
402016
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Artikelen 1–20