Jason Young
Jason Young
Geverifieerd e-mailadres voor mcgill.ca
Geciteerd door
Geciteerd door
Pathways of chaperone-mediated protein folding in the cytosol
JC Young, VR Agashe, K Siegers, FU Hartl
Nature reviews Molecular cell biology 5 (10), 781-791, 2004
Hsp90: a specialized but essential protein-folding tool
JC Young, I Moarefi, FU Hartl
The Journal of cell biology 154 (2), 267-274, 2001
Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70
JC Young, NJ Hoogenraad, FU Hartl
Cell 112 (1), 41-50, 2003
More than folding: localized functions of cytosolic chaperones
JC Young, JM Barral, FU Hartl
Trends in biochemical sciences 28 (10), 541-547, 2003
Peripheral protein quality control removes unfolded CFTR from the plasma membrane
T Okiyoneda, H Barrière, M Bagdány, WM Rabeh, K Du, J Höhfeld, ...
Science 329 (5993), 805-810, 2010
Specific binding of tetratricopeptide repeat proteins to the C-terminal 12-kDa domain of hsp90
JC Young, WMJ Obermann, FU Hartl
Journal of Biological Chemistry 273 (29), 18007-18010, 1998
Thyroid hormone-induced gene expression program for amphibian tail resorption
Z Wang, DD Brown
Journal of Biological Chemistry 268 (22), 16270-16278, 1993
Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co‐chaperone p23
JC Young, FU Hartl
The EMBO journal 19 (21), 5930-5940, 2000
Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange
Y Shomura, Z Dragovic, HC Chang, N Tzvetkov, JC Young, JL Brodsky, ...
Molecular cell 17 (3), 367-379, 2005
Mechanisms of the Hsp70 chaperone system
JC Young
Biochemistry and Cell Biology 88 (2), 291-300, 2010
In vitro evidence that hsp90 contains two independent chaperone sites
JC Young, C Schneider, FU Hartl
FEBS letters 418 (1-2), 139-143, 1997
Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system
A Brychzy, T Rein, KF Winklhofer, FU Hartl, JC Young, WMJ Obermann
The EMBO journal 22 (14), 3613-3623, 2003
Post-translational integration of tail-anchored proteins is facilitated by defined molecular chaperones
BM Abell, C Rabu, P Leznicki, JC Young, S High
Journal of cell science 120 (10), 1743-1751, 2007
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90
A Orthwein, AM Patenaude, EB Affar, A Lamarre, JC Young, JM Di Noia
Journal of Experimental Medicine 207 (12), 2751-2765, 2010
Prediction of novel Bag-1 homologs based on structure/function analysis identifies Snl1p as an Hsp70 co-chaperone in Saccharomyces cerevisiae
H Sondermann, AK Ho, LL Listenberger, K Siegers, I Moarefi, SR Wente, ...
Journal of biological chemistry 277 (36), 33220-33227, 2002
Hsp90 functions in the targeting and outer membrane translocation steps of Tom70-mediated mitochondrial import
ACY Fan, MK Bhangoo, JC Young
Journal of Biological Chemistry 281 (44), 33313-33324, 2006
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import
MK Bhangoo, S Tzankov, ACY Fan, K Dejgaard, DY Thomas, JC Young
Molecular biology of the cell 18 (9), 3414-3428, 2007
Functional divergence between co-chaperones of Hsc70
S Tzankov, MJH Wong, K Shi, C Nassif, JC Young
Journal of Biological Chemistry 283 (40), 27100-27109, 2008
The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation
MC Rosenhagen, C Sõti, U Schmidt, GM Wochnik, FU Hartl, F Holsboer, ...
Molecular Endocrinology 17 (10), 1991-2001, 2003
Essential role of the unusual DNA-binding motif of BAG-1 for inhibition of the glucocorticoid receptor
U Schmidt, GM Wochnik, MC Rosenhagen, JC Young, FU Hartl, ...
Journal of Biological Chemistry 278 (7), 4926-4931, 2003
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