Joe Abisambra
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Primary age-related tauopathy (PART): a common pathology associated with human aging
JF Crary, JQ Trojanowski, JA Schneider, JF Abisambra, EL Abner, ...
Acta neuropathologica 128 (6), 755-766, 2014
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models
MV Lourenco, RL Frozza, GB de Freitas, H Zhang, GC Kincheski, ...
Nature medicine 25 (1), 165-175, 2019
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation
JF Abisambra, UK Jinwal, LJ Blair, JC O'Leary, Q Li, S Brady, L Wang, ...
Journal of Neuroscience 33 (22), 9498-9507, 2013
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules
UK Jinwal, J Koren, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ...
Journal of Neuroscience 30 (2), 591-599, 2010
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ...
Molecular neurodegeneration 5 (1), 1-11, 2010
Interaction of tau with the RNA-binding protein TIA1 regulates tau pathophysiology and toxicity
T Vanderweyde, DJ Apicco, K Youmans-Kidder, PEA Ash, C Cook, ...
Cell reports 15 (7), 1455-1466, 2016
Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau
J Abisambra, UK Jinwal, Y Miyata, J Rogers, L Blair, X Li, SP Seguin, ...
Biological psychiatry 74 (5), 367-374, 2013
Imbalance of Hsp70 family variants fosters tau accumulation
UK Jinwal, E Akoury, JF Abisambra, JC O'Leary III, AD Thompson, LJ Blair, ...
The FASEB Journal 27 (4), 1450-1459, 2013
Pathological tau promotes neuronal damage by impairing ribosomal function and decreasing protein synthesis
S Meier, M Bell, DN Lyons, J Rodriguez-Rivera, A Ingram, SN Fontaine, ...
Journal of Neuroscience 36 (3), 1001-1007, 2016
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice
JF Abisambra, LJ Blair, SE Hill, JR Jones, C Kraft, J Rogers, J Koren, ...
Journal of Neuroscience 30 (46), 15374-15382, 2010
Facilitating Akt clearance via manipulation of Hsp70 activity and levels
J Koren III, UK Jinwal, Y Jin, J O’Leary, JR Jones, AG Johnson, LJ Blair, ...
Journal of biological chemistry 285 (4), 2498-2505, 2010
Hsc70 rapidly engages tau after microtubule destabilization
UK Jinwal, JC O'Leary III, SI Borysov, JR Jones, Q Li, J Koren III, ...
Journal of biological chemistry 285 (22), 16798-16805, 2010
RNA binding proteins co-localize with small tau inclusions in tauopathy
BF Maziuk, DJ Apicco, AL Cruz, L Jiang, PEA Ash, EL da Rocha, C Zhang, ...
Acta neuropathologica communications 6 (1), 1-14, 2018
Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism
A Suntharalingam, JF Abisambra, JC O'Leary III, J Koren III, B Zhang, ...
Journal of Biological Chemistry 287 (48), 40661-40669, 2012
Cdc37/Hsp90 protein complex disruption triggers an autophagic clearance cascade for TDP-43 protein
UK Jinwal, JF Abisambra, J Zhang, S Dharia, JC O'Leary, T Patel, ...
Journal of Biological Chemistry 287 (29), 24814-24820, 2012
The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics
UK Jinwal, JH Trotter, JF Abisambra, J Koren III, LY Lawson, GD Vestal, ...
Journal of Biological Chemistry 286 (19), 16976-16983, 2011
The Diarylheptanoid (+)-aR,11S-Myricanol and Two Flavones from Bayberry (Myrica cerifera) Destabilize the Microtubule-Associated Protein Tau
JR Jones, MD Lebar, UK Jinwal, JF Abisambra, J Koren III, L Blair, ...
Journal of natural products 74 (1), 38-44, 2011
Hsp70 ATPase modulators as therapeutics for Alzheimer’s and other neurodegenerative diseases
UK Jinwal, J Koren III, JC O’Leary III, JR Jones, JF Abisambra, CA Dickey
Molecular and Cellular Pharmacology 2 (2), 43, 2010
Cerebral microvascular accumulation of tau oligomers in Alzheimer’s disease and related tauopathies
DL Castillo-Carranza, AN Nilson, CE Van Skike, JB Jahrling, K Patel, ...
Aging and disease 8 (3), 257, 2017
LDLR expression and localization are altered in mouse and human cell culture models of Alzheimer's disease
JF Abisambra, T Fiorelli, J Padmanabhan, P Neame, I Wefes, H Potter
PloS one 5 (1), e8556, 2010
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