Motomi Osato

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Yoshiaki ItoProfessor, Cancer Science Institute of Singapore, NUSGeverifieerd e-mailadres voor nus.edu.sg
Katsuya ShigesadaretiredGeverifieerd e-mailadres voor nifty.com
Daniel G TenenCancer Science Institute, National University of SingaporeGeverifieerd e-mailadres voor nus.edu.sg
Wee Joo ChngCancer Science Institute of SingaporeGeverifieerd e-mailadres voor nus.edu.sg
Dan LittmanSkirball Institute, NYU School of MedicineGeverifieerd e-mailadres voor med.nyu.edu
Minetaro OgawaInstitute of Molecular Embryology and Genetics, Kumamoto UniversityGeverifieerd e-mailadres voor kumamoto-u.ac.jp
Takuro NakamuraTokyo Medical UniversityGeverifieerd e-mailadres voor umin.net
Hamish S ScottCenter of Cancer BiologyGeverifieerd e-mailadres voor sa.gov.au
Desmond Wai Loon ChinPostdoc, Karolinska InstitutetGeverifieerd e-mailadres voor ki.se
KG YeohNational University of SingaporeGeverifieerd e-mailadres voor nus.edu.sg
Michiaki UnnoTohoku UniveisityGeverifieerd e-mailadres voor surg.med.tohoku.ac.jp
Liqun HuangStony Brook University or National University of SingaporeGeverifieerd e-mailadres voor stonybrookmedicine.edu
Tuan Zea TanCancer Science Institute of SingaporeGeverifieerd e-mailadres voor nus.edu.sg
Stylianos E. AntonarakisProfessor of Genetic Medicine, University of Geneva Medical SchoolGeverifieerd e-mailadres voor unige.ch
Takeshi EgawaWashington University School of MedicineGeverifieerd e-mailadres voor wustl.edu
MJ SunshineUC-San DiegoGeverifieerd e-mailadres voor ucsd.edu
Zilong WenThe Hong Kong University of Science and TechnologyGeverifieerd e-mailadres voor ust.hk
Masatsugu EmaShiga University of Medical Science, Research Center for Animal Life Science, Department of Stem Cells and Human Disease ModelsGeverifieerd e-mailadres voor belle.shiga-med.ac.jp
Seiichi MoriGenome Center, Japanese Foundation for Cancer ResearchGeverifieerd e-mailadres voor jfcr.or.jp
Qi ZengInstitute of Molecular and Cell BiologyGeverifieerd e-mailadres voor imcb.a-star.edu.sg

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Motomi Osato

Cancer Science Institute, National University of Singapore

Geverifieerd e-mailadres voor nus.edu.sg

Leukemia RUNX Transcription factor cis-regulatory element Mouse model


Titel Sorteren op citaties Sorteren op jaar Sorteren op titel	Geciteerd door Geciteerd door	Jaar
Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development I Taniuchi, M Osato, T Egawa, MJ Sunshine, SC Bae, T Komori, Y Ito, ... Cell 111 (5), 621-633, 2002	866	2002
Biallelic and Heterozygous Point Mutations in the Runt Domain of theAML1/PEBP2B Gene Associated With Myeloblastic Leukemias M Osato, N Asou, E Abdalla, K Hoshino, H Yamasaki, T Okubo, ... Blood, The Journal of the American Society of Hematology 93 (6), 1817-1824, 1999	484	1999
In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms … J Michaud, F Wu, M Osato, GM Cottles, M Yanagida, N Asou, ... Blood, The Journal of the American Society of Hematology 99 (4), 1364-1372, 2002	438	2002
MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis CM Koh, M Bezzi, DHP Low, WX Ang, SX Teo, FPH Gay, M Al-Haddawi, ... Nature 523 (7558), 96-100, 2015	375	2015
Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia M Osato Oncogene 23 (24), 4284-4296, 2004	350	2004
Heterozygous PU. 1 mutations are associated with acute myeloid leukemia BU Mueller, T Pabst, M Osato, N Asou, LM Johansen, MD Minden, ... Blood, The Journal of the American Society of Hematology 100 (3), 998-1007, 2002	301	2002
RUNX3 attenuates β-catenin/T cell factors in intestinal tumorigenesis K Ito, ACB Lim, M Salto-Tellez, L Motoda, M Osato, LSH Chuang, ... Cancer cell 14 (3), 226-237, 2008	255	2008
Requirement of Runx1/AML1/PEBP2αB for the generation of haematopoietic cells from endothelial cells T Yokomizo, M Ogawa, M Osato, T Kanno, H Yoshida, T Fujimoto, ... Genes to Cells 6 (1), 13-23, 2001	210	2001
Functional analysis of RUNX2 mutations in Japanese patients with cleidocranial dysplasia demonstrates novel genotype-phenotype correlations T Yoshida, H Kanegane, M Osato, M Yanagida, T Miyawaki, Y Ito, ... The American Journal of Human Genetics 71 (4), 724-738, 2002	207	2002
Identification of stem cells in the epithelium of the stomach corpus and antrum of mice J Matsuo, S Kimura, A Yamamura, CP Koh, MZ Hossain, DL Heng, ... Gastroenterology 152 (1), 218-231. e14, 2017	149	2017
Integrative analysis of RUNX1 downstream pathways and target genes J Michaud, KM Simpson, R Escher, K Buchet-Poyau, T Beissbarth, ... BMC genomics 9, 1-17, 2008	146	2008
Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis B Jacob, M Osato, N Yamashita, CQ Wang, I Taniuchi, DR Littman, ... Blood, The Journal of the American Society of Hematology 115 (8), 1610-1620, 2010	140	2010
PRL-3 initiates tumor angiogenesis by recruiting endothelial cells in vitro and in vivo K Guo, J Li, H Wang, M Osato, JP Tang, SY Quah, BQ Gan, Q Zeng Cancer research 66 (19), 9625-9635, 2006	118	2006
A Runx1 Intronic Enhancer Marks Hemogenic Endothelial Cells and Hematopoietic Stem Cells CEL Ng, T Yokomizo, N Yamashita, B Cirovic, H Jin, Z Wen, Y Ito, M Osato Stem cells 28 (10), 1869-1881, 2010	106	2010
Disruption of Runx1 and Runx3 leads to bone marrow failure and leukemia predisposition due to transcriptional and DNA repair defects CQ Wang, V Krishnan, LS Tay, DWL Chin, CP Koh, JY Chooi, GSS Nah, ... Cell reports 8 (3), 767-782, 2014	104	2014
Requirement for Runx proteins in IgA class switching acting downstream of TGF-β1 and retinoic acid signaling K Watanabe, M Sugai, Y Nambu, M Osato, T Hayashi, M Kawaguchi, ... The Journal of Immunology 184 (6), 2785-2792, 2010	103	2010
Runx1 is involved in primitive erythropoiesis in the mouse T Yokomizo, K Hasegawa, H Ishitobi, M Osato, M Ema, Y Ito, M Yamamoto, ... Blood, The Journal of the American Society of Hematology 111 (8), 4075-4080, 2008	100	2008
Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model M Iwasaki, T Kuwata, Y Yamazaki, NA Jenkins, NG Copeland, M Osato, ... Blood 105 (2), 784-793, 2005	98	2005
Runx1 Protects Hematopoietic Stem/Progenitor Cells from Oncogenic Insult L Motoda, M Osato, N Yamashita, B Jacob, LQ Chen, M Yanagida, H Ida, ... Stem cells 25 (12), 2976-2986, 2007	96	2007
The ability of MLL to bind RUNX1 and methylate H3K4 at PU. 1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations G Huang, X Zhao, L Wang, S Elf, H Xu, X Zhao, G Sashida, Y Zhang, Y Liu, ... Blood, The Journal of the American Society of Hematology 118 (25), 6544-6552, 2011	90	2011

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