Matthew  D Young
Matthew D Young
Wellcome Sanger Institute
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Method Gene ontology analysis for RNA-seq: accounting for selection bias
MD Young, MJ Wakefield, GK Smyth, A Oshlack
From RNA-seq reads to differential expression results
A Oshlack, MD Robinson, MD Young
Genome biology 11 (12), 220, 2010
Intra-tumour diversification in colorectal cancer at the single-cell level
SF Roerink, N Sasaki, H Lee-Six, MD Young, LB Alexandrov, S Behjati, ...
Nature 556 (7702), 457-462, 2018
ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity
MD Young, TA Willson, MJ Wakefield, E Trounson, DJ Hilton, ME Blewitt, ...
Nucleic Acids Research 39 (17), 7415-7427, 2011
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors
MD Young, TJ Mitchell, FAV Braga, MGB Tran, BJ Stewart, JR Ferdinand, ...
Science 361 (6402), 594-599, 2018
BBKNN: fast batch alignment of single cell transcriptomes
K Polański, MD Young, Z Miao, KB Meyer, SA Teichmann, JE Park
Bioinformatics 36 (3), 964-965, 2020
Decoding human fetal liver haematopoiesis
DM Popescu, RA Botting, E Stephenson, K Green, S Webb, L Jardine, ...
Nature 574 (7778), 365-371, 2019
Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma
S Behjati, PS Tarpey, K Haase, H Ye, MD Young, LB Alexandrov, ...
Nature communications 8 (1), 1-8, 2017
SoupX removes ambient RNA contamination from droplet based single cell RNA sequencing data
MD Young, S Behjati
bioRxiv, 303727, 2018
Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2
B Pal, T Bouras, W Shi, F Vaillant, JM Sheridan, N Fu, K Breslin, K Jiang, ...
Cell reports 3 (2), 411-426, 2013
Spatiotemporal immune zonation of the human kidney
BJ Stewart, JR Ferdinand, MD Young, TJ Mitchell, KW Loudon, AM Riding, ...
Science 365 (6460), 1461-1466, 2019
goseq: Gene Ontology testing for RNA-seq datasets
MD Young, MJ Wakefield, GK Smyth, A Oshlack
Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors
ND Anderson, R de Borja, MD Young, F Fuligni, A Rosic, ND Roberts, ...
Science 361 (6405), 2018
The driver landscape of sporadic chordoma
PS Tarpey, S Behjati, MD Young, I Martincorena, LB Alexandrov, ...
Nature communications 8 (1), 1-6, 2017
Recurrent rearrangements of FOS and FOSB define osteoblastoma
MW Fittall, W Mifsud, N Pillay, H Ye, AC Strobl, A Verfaillie, ...
Nature communications 9 (1), 1-6, 2018
The SEQanswers wiki: a wiki database of tools for high-throughput sequencing analysis
JW Li, K Robison, M Martin, A Sjödin, B Usadel, M Young, EC Olivares, ...
Nucleic acids research 40 (D1), D1313-D1317, 2012
Dependence of fragmentation in self-gravitating accretion discs on small-scale structure
MD Young, CJ Clarke
Monthly Notices of the Royal Astronomical Society 451 (4), 3987-3994, 2015
Embryonal precursors of Wilms tumor
THH Coorens, TD Treger, R Al-Saadi, L Moore, MGB Tran, TJ Mitchell, ...
Science 366 (6470), 1247-1251, 2019
Binary accretion rates: dependence on temperature and mass ratio
MD Young, CJ Clarke
Monthly Notices of the Royal Astronomical Society 452 (3), 3085-3091, 2015
An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures
G Collord, P Tarpey, N Kurbatova, I Martincorena, S Moran, M Castro, ...
Scientific reports 8 (1), 1-13, 2018
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