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Kuang-Hueih Chen
Kuang-Hueih Chen
Geverifieerd e-mailadres voor queensu.ca
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Dysregulation of HSG triggers vascular proliferative disorders
KH Chen, X Guo, D Ma, Y Guo, Q Li, D Yang, P Li, X Qiu, S Wen, RP Xiao, ...
Nature cell biology 6 (9), 872-883, 2004
5682004
Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway
X Guo, KH Chen, Y Guo, H Liao, J Tang, RP Xiao
Circulation research 101 (11), 1113-1122, 2007
2562007
Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis
T Shen, M Zheng, C Cao, C Chen, J Tang, W Zhang, H Cheng, KH Chen, ...
Journal of Biological Chemistry 282 (32), 23354-23361, 2007
2392007
Mitochondrial dynamics in pulmonary arterial hypertension
J Ryan, A Dasgupta, J Huston, KH Chen, SL Archer
Journal of molecular medicine 93, 229-242, 2015
1662015
MicroRNA-138 and microRNA-25 down-regulate mitochondrial calcium uniporter, causing the pulmonary arterial hypertension cancer phenotype
Z Hong, KH Chen, A DasGupta, F Potus, K Dunham-Snary, S Bonnet, ...
American journal of respiratory and critical care medicine 195 (4), 515-529, 2017
1352017
Role of mitofusin 2 (Mfn2) in controlling cellular proliferation
KH Chen, A Dasgupta, J Ding, FE Indig, P Ghosh, DL Longo
The FASEB Journal 28 (1), 382, 2014
1312014
Epigenetic dysregulation of the dynamin-related protein 1 binding partners MiD49 and MiD51 increases mitotic mitochondrial fission and promotes pulmonary arterial hypertension …
KH Chen, A Dasgupta, J Lin, F Potus, S Bonnet, J Iremonger, J Fu, ...
Circulation 138 (3), 287-304, 2018
1232018
Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension
L Tian, M Neuber-Hess, J Mewburn, A Dasgupta, K Dunham-Snary, D Wu, ...
Journal of molecular medicine 95, 381-393, 2017
992017
The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease
K Atkins, A Dasgupta, KH Chen, J Mewburn, SL Archer
Clinical Science 130 (21), 1861-1874, 2016
972016
Overexpression of Mitofusin 2 inhibited oxidized low-density lipoprotein induced vascular smooth muscle cell proliferation and reduced atherosclerotic lesion formation in rabbit
Y Guo, K Chen, W Gao, Q Li, L Chen, G Wang, J Tang
Biochemical and biophysical research communications 363 (2), 411-417, 2007
952007
Epigenetic metabolic reprogramming of right ventricular fibroblasts in pulmonary arterial hypertension: a pyruvate dehydrogenase kinase-dependent shift in mitochondrial …
L Tian, D Wu, A Dasgupta, KH Chen, J Mewburn, F Potus, PDA Lima, ...
Circulation research 126 (12), 1723-1745, 2020
912020
Mutation of the protein kinase A phosphorylation site influences the anti-proliferative activity of mitofusin 2
W Zhou, KH Chen, W Cao, J Zeng, H Liao, L Zhao, X Guo
Atherosclerosis 211 (1), 216-223, 2010
832010
Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury
D Wu, A Dasgupta, KH Chen, M Neuber‐Hess, J Patel, TE Hurst, ...
The FASEB Journal 34 (1), 1447-1464, 2020
742020
Tissue inhibitor of metalloproteinases-4 suppresses vascular smooth muscle cell migration and induces cell apoptosis
YH Guo, W Gao, Q Li, PF Li, PY Yao, K Chen
Life sciences 75 (20), 2483-2493, 2004
722004
Increased Drp1-mediated mitochondrial fission promotes proliferation and collagen production by right ventricular fibroblasts in experimental pulmonary arterial hypertension
L Tian, F Potus, D Wu, A Dasgupta, KH Chen, J Mewburn, P Lima, ...
Frontiers in physiology 9, 369543, 2018
712018
Adenovirus-expressed human hyperplasia suppressor gene induces apoptosis in cancer cells
L Wu, Z Li, Y Zhang, P Zhang, X Zhu, J Huang, T Ma, T Lu, Q Song, Q Li, ...
Molecular cancer therapeutics 7 (1), 222-232, 2008
572008
Mitochondria in the pulmonary vasculature in health and disease: oxygen-sensing, metabolism, and dynamics
A Dasgupta, D Wu, L Tian, PY Xiong, KJ Dunham-Snary, KH Chen, ...
Comprehensive physiology 10 (2), 713-765, 2020
472020
Macrophage–NLRP3 activation promotes right ventricle failure in pulmonary arterial hypertension
R Al-Qazazi, PDA Lima, SZ Prisco, F Potus, A Dasgupta, KH Chen, L Tian, ...
American journal of respiratory and critical care medicine 206 (5), 608-624, 2022
412022
Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer
D Wu, A Dasgupta, AD Read, RET Bentley, M Motamed, KH Chen, ...
Free Radical Biology and Medicine 170, 150-178, 2021
382021
Receptor interacting protein 3 suppresses vascular smooth muscle cell growth by inhibition of the phosphoinositide 3-kinase-Akt axis
Q Li, G Li, X Lan, M Zheng, KH Chen, CM Cao, RP Xiao
Journal of biological chemistry 285 (13), 9535-9544, 2010
342010
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Artikelen 1–20