Dysregulation of HSG triggers vascular proliferative disorders KH Chen, X Guo, D Ma, Y Guo, Q Li, D Yang, P Li, X Qiu, S Wen, RP Xiao, ... Nature cell biology 6 (9), 872-883, 2004 | 568 | 2004 |
Mitofusin 2 triggers vascular smooth muscle cell apoptosis via mitochondrial death pathway X Guo, KH Chen, Y Guo, H Liao, J Tang, RP Xiao Circulation research 101 (11), 1113-1122, 2007 | 256 | 2007 |
Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis T Shen, M Zheng, C Cao, C Chen, J Tang, W Zhang, H Cheng, KH Chen, ... Journal of Biological Chemistry 282 (32), 23354-23361, 2007 | 239 | 2007 |
Mitochondrial dynamics in pulmonary arterial hypertension J Ryan, A Dasgupta, J Huston, KH Chen, SL Archer Journal of molecular medicine 93, 229-242, 2015 | 166 | 2015 |
MicroRNA-138 and microRNA-25 down-regulate mitochondrial calcium uniporter, causing the pulmonary arterial hypertension cancer phenotype Z Hong, KH Chen, A DasGupta, F Potus, K Dunham-Snary, S Bonnet, ... American journal of respiratory and critical care medicine 195 (4), 515-529, 2017 | 135 | 2017 |
Role of mitofusin 2 (Mfn2) in controlling cellular proliferation KH Chen, A Dasgupta, J Ding, FE Indig, P Ghosh, DL Longo The FASEB Journal 28 (1), 382, 2014 | 131 | 2014 |
Epigenetic dysregulation of the dynamin-related protein 1 binding partners MiD49 and MiD51 increases mitotic mitochondrial fission and promotes pulmonary arterial hypertension … KH Chen, A Dasgupta, J Lin, F Potus, S Bonnet, J Iremonger, J Fu, ... Circulation 138 (3), 287-304, 2018 | 123 | 2018 |
Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension L Tian, M Neuber-Hess, J Mewburn, A Dasgupta, K Dunham-Snary, D Wu, ... Journal of molecular medicine 95, 381-393, 2017 | 99 | 2017 |
The role of Drp1 adaptor proteins MiD49 and MiD51 in mitochondrial fission: implications for human disease K Atkins, A Dasgupta, KH Chen, J Mewburn, SL Archer Clinical Science 130 (21), 1861-1874, 2016 | 97 | 2016 |
Overexpression of Mitofusin 2 inhibited oxidized low-density lipoprotein induced vascular smooth muscle cell proliferation and reduced atherosclerotic lesion formation in rabbit Y Guo, K Chen, W Gao, Q Li, L Chen, G Wang, J Tang Biochemical and biophysical research communications 363 (2), 411-417, 2007 | 95 | 2007 |
Epigenetic metabolic reprogramming of right ventricular fibroblasts in pulmonary arterial hypertension: a pyruvate dehydrogenase kinase-dependent shift in mitochondrial … L Tian, D Wu, A Dasgupta, KH Chen, J Mewburn, F Potus, PDA Lima, ... Circulation research 126 (12), 1723-1745, 2020 | 91 | 2020 |
Mutation of the protein kinase A phosphorylation site influences the anti-proliferative activity of mitofusin 2 W Zhou, KH Chen, W Cao, J Zeng, H Liao, L Zhao, X Guo Atherosclerosis 211 (1), 216-223, 2010 | 83 | 2010 |
Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury D Wu, A Dasgupta, KH Chen, M Neuber‐Hess, J Patel, TE Hurst, ... The FASEB Journal 34 (1), 1447-1464, 2020 | 74 | 2020 |
Tissue inhibitor of metalloproteinases-4 suppresses vascular smooth muscle cell migration and induces cell apoptosis YH Guo, W Gao, Q Li, PF Li, PY Yao, K Chen Life sciences 75 (20), 2483-2493, 2004 | 72 | 2004 |
Increased Drp1-mediated mitochondrial fission promotes proliferation and collagen production by right ventricular fibroblasts in experimental pulmonary arterial hypertension L Tian, F Potus, D Wu, A Dasgupta, KH Chen, J Mewburn, P Lima, ... Frontiers in physiology 9, 369543, 2018 | 71 | 2018 |
Adenovirus-expressed human hyperplasia suppressor gene induces apoptosis in cancer cells L Wu, Z Li, Y Zhang, P Zhang, X Zhu, J Huang, T Ma, T Lu, Q Song, Q Li, ... Molecular cancer therapeutics 7 (1), 222-232, 2008 | 57 | 2008 |
Mitochondria in the pulmonary vasculature in health and disease: oxygen-sensing, metabolism, and dynamics A Dasgupta, D Wu, L Tian, PY Xiong, KJ Dunham-Snary, KH Chen, ... Comprehensive physiology 10 (2), 713-765, 2020 | 47 | 2020 |
Macrophage–NLRP3 activation promotes right ventricle failure in pulmonary arterial hypertension R Al-Qazazi, PDA Lima, SZ Prisco, F Potus, A Dasgupta, KH Chen, L Tian, ... American journal of respiratory and critical care medicine 206 (5), 608-624, 2022 | 41 | 2022 |
Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer D Wu, A Dasgupta, AD Read, RET Bentley, M Motamed, KH Chen, ... Free Radical Biology and Medicine 170, 150-178, 2021 | 38 | 2021 |
Receptor interacting protein 3 suppresses vascular smooth muscle cell growth by inhibition of the phosphoinositide 3-kinase-Akt axis Q Li, G Li, X Lan, M Zheng, KH Chen, CM Cao, RP Xiao Journal of biological chemistry 285 (13), 9535-9544, 2010 | 34 | 2010 |