Brian M. Baker

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Oleg BorbulevychQuantumBio Inc.Geverifieerd e-mailadres voor quantumbioinc.com
Nishant SinghUniversity of Notre Dame, Ragon Institute of MGH, Harvard and MITGeverifieerd e-mailadres voor mit.edu
Kurt PiepenbrinkAssistant Professor, The University of Nebraska LincolnGeverifieerd e-mailadres voor unl.edu
Zhiping WengProf & Chair, Department of Genomics and Computational Biology, UMASS Medical SchoolGeverifieerd e-mailadres voor umassmed.edu
Pramod K Srivastava PhD MDUniversity of Connecticut School of MedicineGeverifieerd e-mailadres voor uchc.edu
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Brian G. PierceAssociate Professor, Department of Cell Biology and Molecular Genetics, IBBR, University of MarylandGeverifieerd e-mailadres voor umd.edu
Steven A. CorcelliUniversity of Notre Dame, Department of Chemistry and BiochemistryGeverifieerd e-mailadres voor nd.edu
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David ColeHonorary Professor, Cardiff UniversityGeverifieerd e-mailadres voor cf.ac.uk
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George CoukosUniversity Hospital of Lausanne, Ludwig Institute for Cancer ResearchGeverifieerd e-mailadres voor chuv.ch
Nicholas P Restifo, MDCellular Immunotherapy ExplorerGeverifieerd e-mailadres voor marbletx.com
Michal Bassani-SternbergAssistant Professor, Ludwig Institute for Cancer Research, Lausanne & Head of Immunopeptidomics UnitGeverifieerd e-mailadres voor chuv.ch
Jiaqi MaUniversity of Notre DameGeverifieerd e-mailadres voor nd.edu
John J MilesJames Cook UniversityGeverifieerd e-mailadres voor jcu.edu.au
Tyler BorrmanScientist at PACT PharmaGeverifieerd e-mailadres voor umassmed.edu
P* RizkallahSenior Lecturer, Cardiff UniversityGeverifieerd e-mailadres voor cardiff.ac.uk

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Brian M. Baker

Department of Chemistry & Biochemistry, University of Notre Dame

Geverifieerd e-mailadres voor nd.edu - Homepage

structural biology T cells molecular biophysics immunology signaling


Titel Sorteren op citaties Sorteren op jaar Sorteren op titel	Geciteerd door Geciteerd door	Jaar
Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical YH Ding, BM Baker, DN Garboczi, WE Biddison, DC Wiley Immunity 11 (1), 45-56, 1999	465	1999
Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity F Duan, J Duitama, S Al Seesi, CM Ayres, SA Corcelli, AP Pawashe, ... Journal of Experimental Medicine 211 (11), 2231-2248, 2014	428	2014
Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetry BM Baker, KP Murphy Biophysical journal 71 (4), 2049-2055, 1996	395	1996
T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility OY Borbulevych, KH Piepenbrink, BE Gloor, DR Scott, RF Sommese, ... Immunity 31 (6), 885-896, 2009	230	2009
Dissecting the energetics of a protein-protein interaction: the binding of ovomucoid third domain to elastase BM Baker, KP Murphy Journal of molecular biology 268 (2), 557-569, 1997	204	1997
The structure and stability of an HLA-A* 0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site AR Khan, BM Baker, P Ghosh, WE Biddison, DC Wiley The Journal of Immunology 164 (12), 6398, 2000	200	2000
Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling BM Baker, SJ Gagnon, WE Biddison, DC Wiley Immunity 13 (4), 475-484, 2000	178	2000
Prediction of binding energetics from structure using empirical parameterization BM Baker, KP Murphy Methods in enzymology 295, 294-315, 1998	178	1998
TCRs used in cancer gene therapy cross-react with MART-1/Melan-A tumor antigens via distinct mechanisms OY Borbulevych, SM Santhanagopolan, M Hossain, BM Baker The Journal of Immunology 187 (5), 2453-2463, 2011	174	2011
Conformational changes and flexibility in T-cell receptor recognition of peptide–MHC complexes KM Armstrong, KH Piepenbrink, BM Baker Biochemical Journal 415 (Pt 2), 183, 2008	173	2008
Poor immunogenicity of a self/tumor antigen derives from peptide-MHC-I instability and is independent of tolerance Z Yu, MR Theoret, CE Touloukian, DR Surman, SC Garman, ... Journal of Clinical Investigation 114, 551-559, 2004	156	2004
Increased immunogenicity of an anchor-modified tumor-associated antigen is due to the enhanced stability of the peptide/MHC complex: implications for vaccine design OY Borbulevych, TK Baxter, Z Yu, NP Restifo, BM Baker The Journal of Immunology 174 (8), 4812, 2005	143	2005
Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity JJ Adams, S Narayanan, ME Birnbaum, SS Sidhu, SJ Blevins, MH Gee, ... Nature immunology, 2015	130	2015
Two different T cell receptors use different thermodynamic strategies to recognize the same peptide/MHC ligand RL Davis-Harrison, KM Armstrong, BM Baker Journal of molecular biology 346 (2), 533-550, 2005	125	2005
Structures of MART-126/27-35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition OY Borbulevych, FK Insaidoo, TK Baxter, DJ Powell Jr, LA Johnson, ... Journal of molecular biology 372 (5), 1123-1136, 2007	112	2007
Interactions between CLIP-170, tubulin, and microtubules: implications for the mechanism of Clip-170 plus-end tracking behavior ES Folker, BM Baker, HV Goodson Molecular biology of the cell 16 (11), 5373-5384, 2005	112	2005
Identification of a Crucial Energetic Footprint on the α1 Helix of Human Histocompatibility Leukocyte Antigen (Hla)-A2 That Provides Functional Interactions for Recognition by … BM Baker, RV Turner, SJ Gagnon, DC Wiley, WE Biddison The Journal of experimental medicine 193 (5), 551, 2001	100	2001
Conformational melding permits a conserved binding geometry in TCR recognition of foreign and self molecular mimics OY Borbulevych, KH Piepenbrink, BM Baker The Journal of Immunology 186 (5), 2950, 2011	97	2011
Prediction of neo-epitope immunogenicity reveals TCR recognition determinants and provides insight into immunoediting J Schmidt, AR Smith, M Magnin, J Racle, JR Devlin, S Bobisse, J Cesbron, ... Cell Reports Medicine 2 (2), 2021	95	2021
Structural and dynamic control of T‐cell receptor specificity, cross‐reactivity, and binding mechanism BM Baker, DR Scott, SJ Blevins, WF Hawse Immunological Reviews 250 (1), 10-31, 2012	95	2012

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