Initial genome sequencing and analysis of multiple myeloma MA Chapman, MS Lawrence, JJ Keats, K Cibulskis, C Sougnez, ... Nature 471 (7339), 467-472, 2011 | 1692 | 2011 |
Promiscuous mutations activate the noncanonical NF-κB pathway in multiple myeloma JJ Keats, R Fonseca, M Chesi, R Schop, A Baker, WJ Chng, S Van Wier, ... Cancer cell 12 (2), 131-144, 2007 | 1212 | 2007 |
Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy JG Lohr, P Stojanov, SL Carter, P Cruz-Gordillo, MS Lawrence, D Auclair, ... Cancer cell 25 (1), 91-101, 2014 | 1099 | 2014 |
Clonal competition with alternating dominance in multiple myeloma JJ Keats, M Chesi, JB Egan, VM Garbitt, SE Palmer, E Braggio, ... Blood, The Journal of the American Society of Hematology 120 (5), 1067-1076, 2012 | 778 | 2012 |
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling S Vallabhapurapu, A Matsuzawa, WZ Zhang, PH Tseng, JJ Keats, ... Nature immunology 9 (12), 1364-1370, 2008 | 728 | 2008 |
Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides JB Egan, CX Shi, W Tembe, A Christoforides, A Kurdoglu, S Sinari, ... Blood, The Journal of the American Society of Hematology 120 (5), 1060-1066, 2012 | 504 | 2012 |
In multiple myeloma, t (4; 14)(p16; q32) is an adverse prognostic factor irrespective of FGFR3 expression JJ Keats, T Reiman, CA Maxwell, BJ Taylor, LM Larratt, MJ Mant, ... Blood, The Journal of the American Society of Hematology 101 (4), 1520-1529, 2003 | 495 | 2003 |
A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis BA Walker, K Mavrommatis, CP Wardell, TC Ashby, M Bauer, F Davies, ... Leukemia 33 (1), 159-170, 2019 | 407 | 2019 |
Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma BA Walker, K Mavrommatis, CP Wardell, TC Ashby, M Bauer, FE Davies, ... Blood, The Journal of the American Society of Hematology 132 (6), 587-597, 2018 | 407 | 2018 |
Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma C Leung-Hagesteijn, N Erdmann, G Cheung, JJ Keats, AK Stewart, ... Cancer cell 24 (3), 289-304, 2013 | 397 | 2013 |
Classical and/or alternative NF-κB pathway activation in multiple myeloma YN Demchenko, OK Glebov, A Zingone, JJ Keats, PL Bergsagel, ... Blood, The Journal of the American Society of Hematology 115 (17), 3541-3552, 2010 | 349 | 2010 |
Promiscuous MYC locus rearrangements hijack enhancers but mostly super-enhancers to dysregulate MYC expression in multiple myeloma M Affer, M Chesi, WD Chen, JJ Keats, YN Demchenko, K Tamizhmani, ... Leukemia 28 (8), 1725-1735, 2014 | 272 | 2014 |
RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability CA Maxwell, JJ Keats, M Crainie, X Sun, T Yen, E Shibuya, M Hendzel, ... Molecular biology of the cell 14 (6), 2262-2276, 2003 | 250 | 2003 |
Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma G Ledergor, A Weiner, M Zada, SY Wang, YC Cohen, ME Gatt, N Snir, ... Nature medicine 24 (12), 1867-1876, 2018 | 218 | 2018 |
Overexpression of transcripts originating from the MMSET locus characterizes all t (4; 14)(p16; q32)-positive multiple myeloma patients JJ Keats, CA Maxwell, BJ Taylor, MJ Hendzel, M Chesi, PL Bergsagel, ... Blood 105 (10), 4060-4069, 2005 | 199 | 2005 |
Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factor-κB signaling pathways in Waldenstrom's macroglobulinemia E Braggio, JJ Keats, X Leleu, S Van Wier, VH Jimenez-Zepeda, R Valdez, ... Cancer research 69 (8), 3579-3588, 2009 | 189 | 2009 |
Receptor for hyaluronan-mediated motility correlates with centrosome abnormalities in multiple myeloma and maintains mitotic integrity CA Maxwell, JJ Keats, AR Belch, LM Pilarski, T Reiman Cancer research 65 (3), 850-860, 2005 | 163 | 2005 |
High somatic mutation and neoantigen burden are correlated with decreased progression-free survival in multiple myeloma A Miller, Y Asmann, L Cattaneo, E Braggio, J Keats, D Auclair, S Lonial, ... Blood cancer journal 7 (9), e612-e612, 2017 | 148 | 2017 |
Multiple myeloma immunoglobulin lambda translocations portend poor prognosis BG Barwick, P Neri, NJ Bahlis, AK Nooka, MV Dhodapkar, DL Jaye, ... Nature communications 10 (1), 1911, 2019 | 136 | 2019 |
MYC dysregulation in the progression of multiple myeloma K Misund, N Keane, CK Stein, YW Asmann, G Day, S Welsh, SA Van Wier, ... Leukemia 34 (1), 322-326, 2020 | 133 | 2020 |