| O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease NP Marotta, YH Lin, YE Lewis, MR Ambroso, BW Zaro, MT Roth, ... Nature chemistry 7 (11), 913-920, 2015 | 271 | 2015 |
| Synthetic glycopeptides and glycoproteins as tools for biology MR Pratt, CR Bertozzi Chemical Society Reviews 34 (1), 58-68, 2005 | 249 | 2005 |
| Click chemistry in proteomic investigations CG Parker, MR Pratt Cell 180 (4), 605-632, 2020 | 240 | 2020 |
| Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1 BW Zaro, YY Yang, HC Hang, MR Pratt Proceedings of the National Academy of Sciences 108 (20), 8146-8151, 2011 | 237 | 2011 |
| Homogeneous glycopeptides and glycoproteins for biological investigation MJ Grogan, MR Pratt, LA Marcaurelle, CR Bertozzi Annual review of biochemistry 71 (1), 593-634, 2002 | 211 | 2002 |
| α-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson’s disease PM Levine, A Galesic, AT Balana, AL Mahul-Mellier, MX Navarro, ... Proceedings of the National Academy of Sciences 116 (5), 1511-1519, 2019 | 182 | 2019 |
| Solid-phase synthesis of O-linked glycopeptide analogues of enkephalin SA Mitchell, MR Pratt, VJ Hruby, R Polt The Journal of Organic Chemistry 66 (7), 2327-2342, 2001 | 177 | 2001 |
| Probing glycosyltransferase activities with the Staudinger ligation HC Hang, C Yu, MR Pratt, CR Bertozzi Journal of the American Chemical Society 126 (1), 6-7, 2004 | 142 | 2004 |
| Changes in Metabolic Chemical Reporter Structure Yield a Selective Probe of O-GlcNAc Modification KN Chuh, BW Zaro, F Piller, V Piller, MR Pratt Journal of the American Chemical Society 136 (35), 12283-12295, 2014 | 133 | 2014 |
| Structure–activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B RK McGinty, M Köhn, C Chatterjee, KP Chiang, MR Pratt, TW Muir ACS chemical biology 4 (11), 958-968, 2009 | 129 | 2009 |
| Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis JD Mougous, CJ Petzold, RH Senaratne, DH Lee, DL Akey, FL Lin, ... Nature structural & molecular biology 11 (8), 721-729, 2004 | 127 | 2004 |
| Trehalose is required for growth of Mycobacterium smegmatis PJ Woodruff, BL Carlson, B Siridechadilok, MR Pratt, RH Senaratne, ... Journal of Biological Chemistry 279 (28), 28835-28843, 2004 | 126 | 2004 |
| Semisynthetic, site-specific ubiquitin modification of α-synuclein reveals differential effects on aggregation F Meier, T Abeywardana, A Dhall, NP Marotta, J Varkey, R Langen, ... Journal of the American Chemical Society 134 (12), 5468-5471, 2012 | 122 | 2012 |
| Small-molecule-mediated rescue of protein function by an inducible proteolytic shunt MR Pratt, EC Schwartz, TW Muir Proceedings of the National Academy of Sciences 104 (27), 11209-11214, 2007 | 119 | 2007 |
| Deconvoluting the functions of polypeptide N-α-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling MR Pratt, HC Hang, KG Ten Hagen, J Rarick, TA Gerken, LA Tabak, ... Chemistry & biology 11 (7), 1009-1016, 2004 | 118 | 2004 |
| Chemoselective ligation applied to the synthesis of a biantennary N-linked glycoform of CD52 MR Pratt, CR Bertozzi Journal of the American Chemical Society 125 (20), 6149-6159, 2003 | 100 | 2003 |
| O-GlcNAcylation of α-synuclein at serine 87 reduces aggregation without affecting membrane binding YE Lewis, A Galesic, PM Levine, CA De Leon, N Lamiri, CK Brennan, ... ACS chemical biology 12 (4), 1020-1027, 2017 | 93 | 2017 |
| An alkyne–aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells LA Bateman, BW Zaro, SM Miller, MR Pratt Journal of the American Chemical Society 135 (39), 14568-14573, 2013 | 90 | 2013 |
| Chemical methods for encoding and decoding of posttranslational modifications KN Chuh, AR Batt, MR Pratt Cell chemical biology 23 (1), 86-107, 2016 | 87 | 2016 |
| Extent of inhibition of α-synuclein aggregation in vitro by SUMOylation is conjugation site-and SUMO isoform-selective T Abeywardana, MR Pratt Biochemistry 54 (4), 959-961, 2015 | 76 | 2015 |
Balyn W ZaroAssistant Professor, University of California San FranciscoVerified email at ucsf.edu
