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Oncogenic PI3K deregulates transcription and translation AG Bader, S Kang, L Zhao, PK Vogt Nature Reviews Cancer 5 (12), 921-929, 2005 | 1076 | 2005 |
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic S Kang, AG Bader, PK Vogt Proceedings of the National Academy of Sciences 102 (3), 802-807, 2005 | 1025 | 2005 |
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34 JF Wiggins, L Ruffino, K Kelnar, M Omotola, L Patrawala, D Brown, ... Cancer research 70 (14), 5923-5930, 2010 | 811 | 2010 |
Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice P Trang, JF Wiggins, CL Daige, C Cho, M Omotola, D Brown, ... Molecular Therapy 19 (6), 1116-1122, 2011 | 803 | 2011 |
Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors MS Beg, AJ Brenner, J Sachdev, M Borad, YK Kang, J Stoudemire, ... Investigational new drugs 35, 180-188, 2017 | 800 | 2017 |
The let-7 microRNA reduces tumor growth in mouse models of lung cancer A Esquela-Kerscher, P Trang, JF Wiggins, L Patrawala, A Cheng, L Ford, ... Cell cycle 7 (6), 759-764, 2008 | 786 | 2008 |
miR-34–a microRNA replacement therapy is headed to the clinic AG Bader Frontiers in genetics 3, 28826, 2012 | 769 | 2012 |
The promise of microRNA replacement therapy AG Bader, D Brown, M Winkler Cancer research 70 (18), 7027-7030, 2010 | 745 | 2010 |
Regression of murine lung tumors by the let-7 microRNA P Trang, PP Medina, JF Wiggins, L Ruffino, K Kelnar, M Omotola, ... Oncogene 29 (11), 1580-1587, 2010 | 622 | 2010 |
PDL1 Regulation by p53 via miR-34 MA Cortez, C Ivan, D Valdecanas, X Wang, HJ Peltier, Y Ye, L Araujo, ... Journal of the National Cancer Institute 108 (1), djv303, 2016 | 604 | 2016 |
Phase 1 study of MRX34, a liposomal miR-34a mimic, in patients with advanced solid tumours DS Hong, YK Kang, M Borad, J Sachdev, S Ejadi, HY Lim, AJ Brenner, ... British journal of cancer 122 (11), 1630-1637, 2020 | 564 | 2020 |
Cancer-specific mutations in PIK3CA are oncogenic in vivo AG Bader, S Kang, PK Vogt Proceedings of the National Academy of Sciences 103 (5), 1475-1479, 2006 | 530 | 2006 |
Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes F Takeshita, L Patrawala, M Osaki, R Takahashi, Y Yamamoto, N Kosaka, ... Molecular Therapy 18 (1), 181-187, 2010 | 510 | 2010 |
Developing therapeutic microRNAs for cancer AG Bader, D Brown, J Stoudemire, P Lammers Gene therapy 18 (12), 1121-1126, 2011 | 411 | 2011 |
A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer AL Kasinski, K Kelnar, C Stahlhut, E Orellana, J Zhao, E Shimer, S Dysart, ... Oncogene 34 (27), 3547-3555, 2015 | 238 | 2015 |
Therapeutic delivery of miR-200c enhances radiosensitivity in lung cancer MA Cortez, D Valdecanas, X Zhang, Y Zhan, V Bhardwaj, GA Calin, ... Molecular Therapy 22 (8), 1494-1503, 2014 | 219 | 2014 |
Phosphatidylinositol 3-kinase: the oncoprotein PK Vogt, JR Hart, M Gymnopoulos, H Jiang, S Kang, AG Bader, L Zhao, ... Phosphoinositide 3-kinase in Health and Disease: Volume 2, 79-104, 2011 | 169 | 2011 |
Systemic microRNA-34a delivery induces apoptosis and abrogates growth of diffuse large B-cell lymphoma in vivo VJ Craig, A Tzankov, M Flori, CA Schmid, AG Bader, A Müller Leukemia 26 (11), 2421-2424, 2012 | 132 | 2012 |
Inhibition of protein synthesis by Y box-binding protein 1 blocks oncogenic cell transformation AG Bader, PK Vogt Molecular and cellular biology, 2005 | 131 | 2005 |