Finding the sources of missing heritability in a yeast cross JS Bloom, IM Ehrenreich, WT Loo, TLV Lite, L Kruglyak Nature 494 (7436), 234-237, 2013 | 403 | 2013 |
Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity EC Andersen, JP Gerke, JA Shapiro, JR Crissman, R Ghosh, JS Bloom, ... Nature genetics 44 (3), 285, 2012 | 324 | 2012 |
Measuring differential gene expression by short read sequencing: quantitative comparison to 2-channel gene expression microarrays JS Bloom, Z Khan, L Kruglyak, M Singh, AA Caudy BMC genomics 10 (1), 1-10, 2009 | 201 | 2009 |
A variant in the neuropeptide receptor npr-1 is a major determinant of Caenorhabditis elegans growth and physiology EC Andersen, JS Bloom, JP Gerke, L Kruglyak PLoS Genet 10 (2), e1004156, 2014 | 113 | 2014 |
Genetics of single-cell protein abundance variation in large yeast populations FW Albert, S Treusch, AH Shockley, JS Bloom, L Kruglyak Nature 506 (7489), 494-497, 2014 | 111 | 2014 |
Genetic interactions contribute less than additive effects to quantitative trait variation in yeast JS Bloom, I Kotenko, MJ Sadhu, S Treusch, FW Albert, L Kruglyak Nature communications 6 (1), 1-6, 2015 | 98 | 2015 |
Mitochondrial dysfunction, oxidative stress, and apoptosis revealed by proteomic and transcriptomic analyses of the striata in two mouse models of Parkinson’s disease MH Chin, WJ Qian, H Wang, VA Petyuk, JS Bloom, DM Sforza, G Lacan, ... Journal of proteome research 7 (2), 666-677, 2008 | 98 | 2008 |
Accounting for genetic interactions improves modeling of individual quantitative trait phenotypes in yeast SKG Forsberg, JS Bloom, MJ Sadhu, L Kruglyak, Ö Carlborg Nature genetics 49 (4), 497-503, 2017 | 93 | 2017 |
Genetic architecture of highly complex chemical resistance traits across four yeast strains IM Ehrenreich, J Bloom, N Torabi, X Wang, Y Jia, L Kruglyak PLoS Genet 8 (3), e1002570, 2012 | 90 | 2012 |
A Powerful New Quantitative Genetics Platform, Combining Caenorhabditis elegans High-Throughput Fitness Assays with a Large Collection of Recombinant Strains EC Andersen, TC Shimko, JR Crissman, R Ghosh, JS Bloom, HS Seidel, ... G3: Genes, Genomes, Genetics 5 (5), 911-920, 2015 | 72 | 2015 |
CRISPR-directed mitotic recombination enables genetic mapping without crosses MJ Sadhu, JS Bloom, L Day, L Kruglyak Science 352 (6289), 1113-1116, 2016 | 71 | 2016 |
A practical algorithm for finding maximal exact matches in large sequence datasets using sparse suffix arrays Z Khan, JS Bloom, L Kruglyak, M Singh Bioinformatics 25 (13), 1609-1616, 2009 | 71 | 2009 |
Genetics of trans-regulatory variation in gene expression FW Albert, JS Bloom, J Siegel, L Day, L Kruglyak Elife 7, e35471, 2018 | 54 | 2018 |
Protein quantification across hundreds of experimental conditions Z Khan, JS Bloom, BA Garcia, M Singh, L Kruglyak Proceedings of the National Academy of Sciences 106 (37), 15544-15548, 2009 | 50 | 2009 |
Genome to phenome mapping in apple using historical data Z Migicovsky, KM Gardner, D Money, J Sawler, JS Bloom, P Moffett, ... The Plant Genome 9 (2), plantgenome2015.11.0113, 2016 | 47 | 2016 |
Genetic variation in adaptability and pleiotropy in budding yeast ER Jerison, S Kryazhimskiy, JK Mitchell, JS Bloom, L Kruglyak, MM Desai Elife 6, e27167, 2017 | 42 | 2017 |
Genetic mapping of MAPK-mediated complex traits across S. cerevisiae S Treusch, FW Albert, JS Bloom, IE Kotenko, L Kruglyak PLoS Genet 11 (1), e1004913, 2015 | 42 | 2015 |
Highly parallel genome variant engineering with CRISPR–Cas9 MJ Sadhu, JS Bloom, L Day, JJ Siegel, S Kosuri, L Kruglyak Nature genetics 50 (4), 510-514, 2018 | 41 | 2018 |
Quantitative proteomics reveals direct and indirect alterations in the histone code following methyltransferase knockdown MD Plazas-Mayorca, JS Bloom, U Zeissler, G Leroy, NL Young, ... Molecular BioSystems 6 (9), 1719-1729, 2010 | 38 | 2010 |
Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids CC Park, S Ahn, JS Bloom, A Lin, RT Wang, T Wu, A Sekar, AH Khan, ... Nature genetics 40 (4), 421, 2008 | 36 | 2008 |