Marcus Groettrup
Marcus Groettrup
Professor for Immunology, Konstanz University
Geverifieerd e-mailadres voor uni-konstanz.de - Homepage
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Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance
A Limmer, J Ohl, C Kurts, HG Ljunggren, Y Reiss, M Groettrup, ...
Nature medicine 6 (12), 1348-1354, 2000
7402000
Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells
E Scandella, Y Men, S Gillessen, R Forster, M Groettrup
Blood, The Journal of the American Society of Hematology 100 (4), 1354-1361, 2002
5972002
A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis
T Muchamuel, M Basler, MA Aujay, E Suzuki, KW Kalim, C Lauer, ...
Nature medicine 15 (7), 781-787, 2009
5502009
Analysis and expression of a cloned pre-T cell receptor gene
C Saint-Ruf, K Ungewiss, M Groettrup, L Bruno, HJ Fehling, ...
Science 266 (5188), 1208-1212, 1994
5161994
A role for the proteasome regulator PA28α in antigen presentation
M Groettrup, A Soza, M Eggers, L Kuehn, TP Dick, H Schild, ...
Nature 381 (6578), 166-168, 1996
4331996
Immuno-and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity
EM Huber, M Basler, R Schwab, W Heinemeyer, CJ Kirk, M Groettrup, ...
Cell 148 (4), 727-738, 2012
4272012
A novel disulfide-linked heterodimer on pre—T cells consists of the T cell receptor β chain and a 33 kd glycoprotein
M Groettrup, K Ungewiss, O Azogui, R Palacios, MJ Owen, AC Hayday, ...
Cell 75 (2), 283-294, 1993
4081993
Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands
TP Dick, T Ruppert, M Groettrup, PM Kloetzel, L Kuehn, UH Koszinowski, ...
Cell 86 (2), 253-262, 1996
3511996
An inhibitor of HIV-1 protease modulates proteasome activity, antigen presentation, and T cell responses
P André, M Groettrup, P Klenerman, R De Giuli, BL Booth, V Cerundolo, ...
Proceedings of the National Academy of Sciences 95 (22), 13120-13124, 1998
3341998
Proteasomes in immune cells: more than peptide producers?
M Groettrup, CJ Kirk, M Basler
Nature Reviews Immunology 10 (1), 73-78, 2010
3222010
TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses
E Schlosser, M Mueller, S Fischer, S Basta, DH Busch, B Gander, ...
Vaccine 26 (13), 1626-1637, 2008
3202008
The interferon-γ-inducible 11 S regulator (PA28) and the LMP2/LMP7 subunits govern the peptide production by the 20 S proteasome in vitro
M Groettrup, T Ruppert, L Kuehn, M Seeger, S Standera, U Koszinowski, ...
Journal of Biological Chemistry 270 (40), 23808-23815, 1995
2851995
Peptide antigen production by the proteasome: complexity provides efficiency
M Groettrup, A Soza, U Kuckelkorn, PM Kloetzel
Immunology today 17 (9), 429-435, 1996
2801996
The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome
M Groettrup, S Standera, R Stohwasser, PM Kloetzel
Proceedings of the National Academy of Sciences 94 (17), 8970-8975, 1997
2711997
CCL19/CCL21-triggered signal transduction and migration of dendritic cells requires prostaglandin E2
E Scandella, Y Men, DF Legler, S Gillessen, L Prikler, B Ludewig, ...
Blood 103 (5), 1595-1601, 2004
2622004
Prevention of experimental colitis by a selective inhibitor of the immunoproteasome
M Basler, M Dajee, C Moll, M Groettrup, CJ Kirk
The Journal of Immunology 185 (1), 634-641, 2010
2372010
A third interferon‐γ‐induced subunit exchange in the 20S proteasome
M Groettrup, R Kraft, S Kostka, S Standera, R Stohwasser, PM Kloetzel
European journal of immunology 26 (4), 863-869, 1996
2321996
The immunoproteasome in antigen processing and other immunological functions
M Basler, CJ Kirk, M Groettrup
Current opinion in immunology 25 (1), 74-80, 2013
2272013
Dendritic cells up‐regulate immunoproteasomes and the proteasome regulator PA28 during maturation
A Macagno, M Gilliet, F Sallusto, A Lanzavecchia, FO Nestle, M Groettrup
European journal of immunology 29 (12), 4037-4042, 1999
2201999
A single residue exchange within a viral CTL epitope alters proteasome-mediated degradation resulting in lack of antigen presentation
F Ossendorp, M Eggers, A Neisig, T Ruppert, M Groettrup, A Sijts, ...
Immunity 5 (2), 115-124, 1996
2201996
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Artikelen 1–20