|Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells|
G Gallina, L Dolcetti, P Serafini, C De Santo, I Marigo, MP Colombo, ...
The Journal of clinical investigation 116 (10), 2777-2790, 2006
|Myeloid suppressor cells in cancer: recruitment, phenotype, properties, and mechanisms of immune suppression|
P Serafini, I Borrello, V Bronte
Seminars in cancer biology 16 (1), 53-65, 2006
|Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells|
P Serafini, S Mgebroff, K Noonan, I Borrello
Cancer research 68 (13), 5439-5449, 2008
|Tumor‐induced tolerance and immune suppression by myeloid derived suppressor cells|
I Marigo, L Dolcetti, P Serafini, P Zanovello, V Bronte
Immunological reviews 222 (1), 162-179, 2008
|Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function|
P Serafini, K Meckel, M Kelso, K Noonan, J Califano, W Koch, L Dolcetti, ...
The Journal of experimental medicine 203 (12), 2691-2702, 2006
|Myeloid suppressor lines inhibit T cell responses by an NO-dependent mechanism|
A Mazzoni, V Bronte, A Visintin, JH Spitzer, E Apolloni, P Serafini, ...
The Journal of Immunology 168 (2), 689-695, 2002
|Identification of a CD11b+/Gr-1+/CD31+ myeloid progenitor capable of activating or suppressing CD8+T cells|
V Bronte, E Apolloni, A Cabrelle, R Ronca, P Serafini, P Zamboni, ...
Blood, The Journal of the American Society of Hematology 96 (12), 3838-3846, 2000
|L-arginine metabolism in myeloid cells controls T-lymphocyte functions|
V Bronte, P Serafini, A Mazzoni, DM Segal, P Zanovello
Trends in immunology 24 (6), 301-305, 2003
|High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells|
P Serafini, R Carbley, KA Noonan, G Tan, V Bronte, I Borrello
Cancer research 64 (17), 6337-6343, 2004
|IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice|
V Bronte, P Serafini, C De Santo, I Marigo, V Tosello, A Mazzoni, ...
The Journal of Immunology 170 (1), 270-278, 2003
|Derangement of immune responses by myeloid suppressor cells|
P Serafini, C De Santo, I Marigo, S Cingarlini, L Dolcetti, G Gallina, ...
Cancer Immunology, Immunotherapy 53 (2), 64-72, 2004
|Nitroaspirin corrects immune dysfunction in tumor-bearing hosts and promotes tumor eradication by cancer vaccination|
C De Santo, P Serafini, I Marigo, L Dolcetti, M Bolla, P Del Soldato, ...
Proceedings of the National Academy of Sciences 102 (11), 4185-4190, 2005
|Tumor-induced immune dysfunctions caused by myeloid suppressor cells|
V Bronte, P Serafini, E Apolloni, P Zanovello
Journal of immunotherapy 24 (6), 431-446, 2001
|Immortalized myeloid suppressor cells trigger apoptosis in antigen-activated T lymphocytes|
E Apolloni, V Bronte, A Mazzoni, P Serafini, A Cabrelle, DM Segal, ...
The Journal of Immunology 165 (12), 6723-6730, 2000
|Aptamer-mediated blockade of IL4Rα triggers apoptosis of MDSCs and limits tumor progression|
F Roth, C Adriana, JL Vella, A Zoso, L Inverardi, P Serafini
Cancer research 72 (6), 1373-1383, 2012
|Tadalafil reduces myeloid-derived suppressor cells and regulatory T cells and promotes tumor immunity in patients with head and neck squamous cell carcinoma|
DT Weed, JL Vella, IM Reis, C Adriana, C Gomez, Z Sargi, R Nazarian, ...
Clinical Cancer Research 21 (1), 39-48, 2015
|Activated marrow-infiltrating lymphocytes effectively target plasma cells and their clonogenic precursors|
K Noonan, W Matsui, P Serafini, R Carbley, G Tan, J Khalili, M Bonyhadi, ...
Cancer research 65 (5), 2026-2034, 2005
|Tadalafil augments tumor specific immunity in patients with head and neck squamous cell carcinoma|
JA Califano, Z Khan, KA Noonan, L Rudraraju, Z Zhang, H Wang, ...
Clinical Cancer Research 21 (1), 30-38, 2015
|Myeloid derived suppressor cells in physiological and pathological conditions: the good, the bad, and the ugly|
Immunologic research 57 (1-3), 172-184, 2013
|Peptide-conjugated PAMAM dendrimer as a universal DNA vaccine platform to target antigen-presenting cells|
P Daftarian, AE Kaifer, W Li, BB Blomberg, D Frasca, F Roth, ...
Cancer research 71 (24), 7452-7462, 2011