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Sook-Kyung Lee
Sook-Kyung Lee
Research Associate at University of North Carolina
Verified email at med.unc.edu
Title
Cited by
Cited by
Year
Viral protease inhibitors
J Anderson, C Schiffer, SK Lee, R Swanstrom
Antiviral strategies, 85-110, 2009
1772009
The choreography of HIV-1 proteolytic processing and virion assembly
SK Lee, M Potempa, R Swanstrom
Journal of Biological Chemistry 287 (49), 40867-40874, 2012
1622012
A Strongly Transdominant Mutation in the Human Immunodeficiency Virus Type 1 gag Gene Defines an Achilles Heel in the Virus Life Cycle
SK Lee, J Harris, R Swanstrom
Journal of virology 83 (17), 8536-8543, 2009
1002009
Context surrounding processing sites is crucial in determining cleavage rate of a subset of processing sites in HIV-1 Gag and Gag-Pro-Pol polyprotein precursors by viral protease
SK Lee, M Potempa, M Kolli, A Özen, CA Schiffer, R Swanstrom
Journal of Biological Chemistry 287 (16), 13279-13290, 2012
602012
Interplay between single resistance-associated mutations in the HIV-1 protease and viral infectivity, protease activity, and inhibitor sensitivity
GJ Henderson, SK Lee, DM Irlbeck, J Harris, M Kline, E Pollom, N Parkin, ...
Antimicrobial agents and chemotherapy 56 (2), 623-633, 2012
442012
In vitro analysis of an RNA binding site within the N-terminal 30 amino acids of the southern cowpea mosaic virus coat protein
SK Lee, DL Hacker
Virology 286 (2), 317-327, 2001
332001
Quantification of the latent HIV-1 reservoir using ultra deep sequencing and primer ID in a viral outgrowth assay
SK Lee, S Zhou, PL Baldoni, E Spielvogel, NM Archin, MG Hudgens, ...
JAIDS Journal of Acquired Immune Deficiency Syndromes 74 (2), 221-228, 2017
312017
Elucidating the interdependence of drug resistance from combinations of mutations
DA Ragland, TW Whitfield, SK Lee, R Swanstrom, KB Zeldovich, ...
Journal of chemical theory and computation 13 (11), 5671-5682, 2017
302017
Long-range recombination gradient between HIV-1 subtypes B and C variants caused by sequence differences in the dimerization initiation signal region
MPS Chin, SK Lee, J Chen, OA Nikolaitchik, DA Powell, MJ Fivash Jr, ...
Journal of molecular biology 377 (5), 1324-1333, 2008
272008
Cooperative effect of gag proteins p12 and capsid during early events of murine leukemia virus replication
SK Lee, K Nagashima, WS Hu
Journal of virology 79 (7), 4159-4169, 2005
272005
HIV-1 protease uses bi-specific S2/S2′ subsites to optimize cleavage of two classes of target sites
M Potempa, SK Lee, NK Yilmaz, EA Nalivaika, A Rogers, E Spielvogel, ...
Journal of molecular biology 430 (24), 5182-5195, 2018
202018
The triple threat of HIV-1 protease inhibitors
M Potempa, SK Lee, R Wolfenden, R Swanstrom
The Future of HIV-1 Therapeutics: Resistance Is Futile?, 203-241, 2015
192015
A direct interaction with RNA dramatically enhances the catalytic activity of the HIV-1 protease in vitro
M Potempa, E Nalivaika, D Ragland, SK Lee, CA Schiffer, R Swanstrom
Journal of molecular biology 427 (14), 2360-2378, 2015
152015
Membrane activity of the southern cowpea mosaic virus coat protein: the role of basic amino acids, helix-forming potential, and lipid composition
SK Lee, C Dabney-Smith, DL Hacker, BD Bruce
Virology 291 (2), 299-310, 2001
152001
A sensitive assay using a native protein substrate for screening HIV-1 maturation inhibitors targeting the protease cleavage site between the matrix and capsid
SK Lee, N Cheng, E Hull-Ryde, M Potempa, CA Schiffer, W Janzen, ...
Biochemistry 52 (29), 4929-4940, 2013
122013
Capsid is an important determinant for functional complementation of murine leukemia virus and spleen necrosis virus Gag proteins
SK Lee, V Boyko, WS Hu
Virology 360 (2), 388-397, 2007
102007
Development of a novel screening strategy designed to discover a new class of HIV drugs
N Cheng, SK Lee, PS Donover, M Reichman, CA Schiffer, EA Hull-Ryde, ...
Journal of laboratory automation 19 (3), 297-303, 2014
82014
Assay to measure the latent reservoir of replication-competent HIV-1 in suppressed patients based on ultra deep sequencing
SK Lee, S Zhou, N Archin, D Margolis, R Swanstrom
Journal of the International Aids Society 18, 2015
22015
Structure-based design, synthesis, evaluation and x-ray crystal structure analysis of HIV-1 protease inhibitors with modified P1, P1'and P2'groups
L Rusere, A Ali, G Lockbaum, SK Lee, R Swanstrom, C Schiffer
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
Deep sequencing analysis reveals novel resistance pathways to potent human immunodeficiency virus type 1 (HIV-1) protease inhibitors
SK Lee, S Zhou, J Paulsen, CA Schiffer, R Swanstrom
ANTIVIRAL THERAPY 19, A132-A132, 2014
2014
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