Jack Taunton
Jack Taunton
Geverifieerd e-mailadres voor ucsf.edu
Geciteerd door
Geciteerd door
A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p
J Taunton, CA Hassig, SL Schreiber
Science 272 (5260), 408-411, 1996
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature 583 (7816), 459-468, 2020
RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation
PP Roux, D Shahbazian, H Vu, MK Holz, MS Cohen, J Taunton, ...
Journal of Biological Chemistry 282 (19), 14056-14064, 2007
Structural bioinformatics-based design of selective, irreversible kinase inhibitors
MS Cohen, C Zhang, KM Shokat, J Taunton
Science 308 (5726), 1318-1321, 2005
The promise and peril of chemical probes
CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ...
Nature Chemical Biology 11 (8), 536-541, 2015
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity
D Shahbazian, PP Roux, V Mieulet, MS Cohen, B Raught, J Taunton, ...
The EMBO journal 25 (12), 2781-2791, 2006
High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases
F Chen, SM Pruett-Miller, Y Huang, M Gjoka, K Duda, J Taunton, ...
Nature methods 8 (9), 753-755, 2011
Phase separation of signaling molecules promotes T cell receptor signal transduction
X Su, JA Ditlev, E Hui, W Xing, S Banjade, J Okrut, DS King, J Taunton, ...
Science 352 (6285), 595-599, 2016
Actin-Dependent Propulsion of Endosomes and Lysosomes by Recruitment of N-Wasp
J Taunton, BA Rowning, ML Coughlin, M Wu, RT Moon, TJ Mitchison, ...
The Journal of cell biology 148 (3), 519-530, 2000
Reversible targeting of noncatalytic cysteines with chemically tuned electrophiles
IM Serafimova, MA Pufall, S Krishnan, K Duda, MS Cohen, RL Maglathlin, ...
Nature chemical biology 8 (5), 471-476, 2012
Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains
MA Puthenveedu, B Lauffer, P Temkin, R Vistein, P Carlton, K Thorn, ...
Cell 143 (5), 761-773, 2010
Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway
SW Kang, NS Rane, SJ Kim, JL Garrison, J Taunton, RS Hegde
Cell 127 (5), 999-1013, 2006
Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload
S Oyadomari, C Yun, EA Fisher, N Kreglinger, G Kreibich, M Oyadomari, ...
Cell 126 (4), 727-739, 2006
Prolonged and tunable residence time using reversible covalent kinase inhibitors
JM Bradshaw, JM McFarland, VO Paavilainen, A Bisconte, D Tam, ...
Nature chemical biology 11 (7), 525-531, 2015
Synthesis of natural and modified trapoxins, useful reagents for exploring histone deacetylase function
J Taunton, JL Collins, SL Schreiber
Journal of the American Chemical Society 118 (43), 10412-10422, 1996
The Role of p58IPK in Protecting the Stressed Endoplasmic Reticulum
DT Rutkowski, SW Kang, AG Goodman, JL Garrison, J Taunton, MG Katze, ...
Molecular biology of the cell 18 (9), 3681-3691, 2007
A polybasic motif allows N-WASP to act as a sensor of PIP2 density
V Papayannopoulos, C Co, KE Prehoda, S Snapper, J Taunton, WA Lim
Molecular cell 17 (2), 181-191, 2005
RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells
U Doehn, C Hauge, SR Frank, CJ Jensen, K Duda, JV Nielsen, ...
Molecular cell 35 (4), 511-522, 2009
Mechanism of actin network attachment to moving membranes: barbed end capture by N-WASP WH2 domains
C Co, DT Wong, S Gierke, V Chang, J Taunton
Cell 128 (5), 901-913, 2007
Covalent docking of large libraries for the discovery of chemical probes
N London, RM Miller, S Krishnan, K Uchida, JJ Irwin, O Eidam, L Gibold, ...
Nature chemical biology 10 (12), 1066-1072, 2014
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