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Ronald J Hause, Jr.
Ronald J Hause, Jr.
Senior Vice President, Analytics & Informatics, Shape Therapeutics
Geverifieerd e-mailadres voor shapetx.com
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Classification and characterization of microsatellite instability across 18 cancer types
RJ Hause, CC Pritchard, J Shendure, SJ Salipante
Nature medicine 22 (11), 1342-1350, 2016
8762016
Saturation editing of genomic regions by multiplex homology-directed repair
GM Findlay, EA Boyle, RJ Hause, JC Klein, J Shendure
Nature, 2014
3952014
Multiplex assessment of protein variant abundance by massively parallel sequencing
KA Matreyek, LM Starita, JJ Stephany, B Martin, MA Chiasson, VE Gray, ...
Nature genetics 50 (6), 874-882, 2018
3682018
Massively parallel functional analysis of BRCA1 RING domain variants
LM Starita, DL Young, M Islam, JO Kitzman, J Gullingsrud, RJ Hause, ...
Genetics 200 (2), 413-422, 2015
3292015
Quantitative missense variant effect prediction using large-scale mutagenesis data
VE Gray, RJ Hause, J Luebeck, J Shendure, DM Fowler
Cell systems 6 (1), 116-124. e3, 2018
1832018
Caffeic acid phenethyl ester suppresses the proliferation of human prostate cancer cells through inhibition of p70S6K and Akt signaling networks
CP Chuu, HP Lin, MF Ciaccio, JM Kokontis, RJ Hause Jr, RA Hiipakka, ...
Cancer Prevention Research 5 (5), 788-797, 2012
1432012
Analysis of large-scale mutagenesis data to assess the impact of single amino acid substitutions
VE Gray, RJ Hause, DM Fowler
Genetics 207 (1), 53-61, 2017
1312017
Mapping 3D genome architecture through in situ DNase Hi-C
V Ramani, DA Cusanovich, RJ Hause, W Ma, R Qiu, X Deng, CA Blau, ...
Nature protocols 11 (11), 2104-2121, 2016
1162016
Natural Genetic Variation for Growth and Development Revealed by High-Throughput Phenotyping in Arabidopsis thaliana
X Zhang, RJ Hause Jr, JO Borevitz
G3: Genes| Genomes| Genetics 2 (1), 29-34, 2012
762012
Anti–B-cell maturation antigen chimeric antigen receptor T cell function against multiple myeloma is enhanced in the presence of lenalidomide
M Works, N Soni, C Hauskins, C Sierra, A Baturevych, JC Jones, W Curtis, ...
Molecular cancer therapeutics 18 (12), 2246-2257, 2019
712019
Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors
RJ Hause Jr, KK Leung, JL Barkinge, MF Ciaccio, C Chuu, RB Jones
Public Library of Science 7 (9), e44471, 2012
702012
Antitumor potency of an anti-CD19 chimeric antigen receptor T-cell therapy, lisocabtagene maraleucel in combination with ibrutinib or acalabrutinib
JS Qin, TG Johnstone, A Baturevych, RJ Hause, SP Ragan, CR Clouser, ...
Journal of immunotherapy 43 (4), 107-120, 2020
672020
Accurate pan-cancer molecular diagnosis of microsatellite instability by single-molecule molecular inversion probe capture and high-throughput sequencing
A Waalkes, N Smith, K Penewit, J Hempelmann, EQ Konnick, RJ Hause, ...
Clinical chemistry 64 (6), 950-958, 2018
612018
Identification and Validation of Genetic Variants that Influence Transcription Factor and Cell Signaling Protein Levels
RJ Hause, AL Stark, NN Antao, LK Gorsic, SH Chung, CD Brown, ...
The American Journal of Human Genetics, 2014
572014
Investigating models of protein function and allostery with a widespread mutational analysis of a light-activated protein
JP Zayner, C Antoniou, AR French, RJ Hause, TR Sosnick
Biophysical journal 105 (4), 1027-1036, 2013
562013
Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy
AL Stark, RJ Hause Jr, LK Gorsic, NN Antao, SS Wong, SH Chung, DF Gill, ...
PLoS genetics 10 (4), e1004192, 2014
372014
Targeted protein-omic methods are bridging the gap between proteomic and hypothesis-driven protein analysis approaches
RJ Hause, HD Kim, KK Leung, RB Jones
Expert Review of Proteomics 8 (5), 565-575, 2011
322011
Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome
KK Leung, RJ Hause, JL Barkinge, MF Ciaccio, CP Chuu, RB Jones
Molecular & Cellular Proteomics 13 (7), 1705-1723, 2014
312014
Single-cell sequencing reveals αβ chain pairing shapes the T cell repertoire
K Grigaityte, JA Carter, SJ Goldfless, EW Jeffery, RJ Hause, Y Jiang, ...
BioRxiv, 213462, 2017
262017
Identifying optimal loci for the molecular diagnosis of microsatellite instability
DR Long, A Waalkes, VP Panicker, RJ Hause Jr, SJ Salipante
Clinical chemistry 66 (10), 1310-1318, 2020
212020
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