Glutamate metabolism and recycling at the excitatory synapse in health and neurodegeneration JV Andersen, KH Markussen, E Jakobsen, A Schousboe, ... Neuropharmacology 196, 108719, 2021 | 193 | 2021 |
The energetic brain–A review from students to students MP Bordone, MM Salman, HE Titus, E Amini, JV Andersen, B Chakraborti, ... Journal of neurochemistry 151 (2), 139-165, 2019 | 173 | 2019 |
Astrocyte energy and neurotransmitter metabolism in Alzheimer’s disease: integration of the glutamate/GABA-glutamine cycle JV Andersen, A Schousboe, A Verkhratsky Progress in neurobiology 217, 102331, 2022 | 85 | 2022 |
Integrative characterization of the R6/2 mouse model of Huntington’s disease reveals dysfunctional astrocyte metabolism NH Skotte, JV Andersen, A Santos, BI Aldana, CW Willert, A Nørremølle, ... Cell Reports 23 (7), 2211-2224, 2018 | 78 | 2018 |
Alterations in cerebral cortical glucose and glutamine metabolism precedes amyloid plaques in the APPswe/PSEN1dE9 mouse model of Alzheimer’s disease JV Andersen, SK Christensen, BI Aldana, JD Nissen, H Tanila, ... Neurochemical research 42, 1589-1598, 2017 | 69 | 2017 |
Deficient astrocyte metabolism impairs glutamine synthesis and neurotransmitter homeostasis in a mouse model of Alzheimer's disease JV Andersen, SK Christensen, EW Westi, M Diaz-delCastillo, H Tanila, ... Neurobiology of disease 148, 105198, 2021 | 65 | 2021 |
Regulation of translation by site-specific ribosomal RNA methylation MD Jansson, SJ Häfner, K Altinel, D Tehler, N Krogh, E Jakobsen, ... Nature structural & molecular biology 28 (11), 889-899, 2021 | 54 | 2021 |
Hippocampal disruptions of synaptic and astrocyte metabolism are primary events of early amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease JV Andersen, NH Skotte, SK Christensen, FS Polli, M Shabani, ... Cell Death & Disease 12 (11), 954, 2021 | 48 | 2021 |
Deletion of neuronal GLT-1 in mice reveals its role in synaptic glutamate homeostasis and mitochondrial function LF McNair, JV Andersen, BI Aldana, MC Hohnholt, JD Nissen, Y Sun, ... Journal of Neuroscience 39 (25), 4847-4863, 2019 | 46 | 2019 |
Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply JV Andersen, EW Westi, E Jakobsen, N Urruticoechea, K Borges, ... Molecular brain 14, 1-13, 2021 | 45 | 2021 |
Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation MC Hohnholt, VH Andersen, JV Andersen, SK Christensen, M Karaca, ... Journal of Cerebral Blood Flow & Metabolism 38 (10), 1754-1768, 2018 | 42 | 2018 |
Metabolic Characterization of Acutely Isolated Hippocampal and Cerebral Cortical Slices Using [U-13C]Glucose and [1,2-13C]Acetate as Substrates LF McNair, R Kornfelt, AB Walls, JV Andersen, BI Aldana, JD Nissen, ... Neurochemical Research 42, 810-826, 2017 | 38 | 2017 |
Functional metabolic mapping reveals highly active branched-chain amino acid metabolism in human astrocytes, which is impaired in iPSC-derived astrocytes in Alzheimer's disease C Salcedo, JV Andersen, KT Vinten, LH Pinborg, HS Waagepetersen, ... Frontiers in aging neuroscience 13, 736580, 2021 | 37 | 2021 |
Improved cerebral energetics and ketone body metabolism in db/db mice JV Andersen, SK Christensen, JD Nissen, HS Waagepetersen Journal of Cerebral Blood Flow & Metabolism 37 (3), 1137-1147, 2017 | 37 | 2017 |
Extensive astrocyte metabolism of γ‐aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex JV Andersen, E Jakobsen, EW Westi, MEK Lie, CM Voss, BI Aldana, ... Glia 68 (12), 2601-2612, 2020 | 36 | 2020 |
Distinct differences in rates of oxygen consumption and ATP synthesis of regionally isolated non‐synaptic mouse brain mitochondria JV Andersen, E Jakobsen, HS Waagepetersen, BI Aldana Journal of Neuroscience Research 97 (8), 961-974, 2019 | 33 | 2019 |
Impaired hippocampal glutamate and glutamine metabolism in the db/db mouse model of type 2 diabetes mellitus JV Andersen, JD Nissen, SK Christensen, KH Markussen, ... Neural Plasticity 2017, 2017 | 33 | 2017 |
AMP‐activated protein kinase (AMPK) regulates astrocyte oxidative metabolism by balancing TCA cycle dynamics CM Voss, JV Andersen, E Jakobsen, O Siamka, M Karaca, P Maechler, ... Glia 68 (9), 1824-1839, 2020 | 31 | 2020 |
Specificity of exogenous acetate and glutamate as astrocyte substrates examined in acute brain slices from female mice using methionine sulfoximine (MSO) to inhibit glutamine … JV Andersen, LF McNair, A Schousboe, HS Waagepetersen Journal of Neuroscience Research 95 (11), 2207-2216, 2017 | 27 | 2017 |
The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms E Jakobsen, SC Lange, JV Andersen, C Desler, HF Kihl, MC Hohnholt, ... Biochemical Pharmacology 155, 92-101, 2018 | 24 | 2018 |