Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. FM Sladek, WM Zhong, E Lai, JE Darnell Genes & development 4 (12b), 2353-2365, 1990 | 1274 | 1990 |
A unified nomenclature system for the nuclear receptor superfamily J Auwerx, E Baulieu, M Beato, M Becker-Andre, PH Burbach, G Camerino, ... Cell 97 (2), 161-163, 1999 | 1171 | 1999 |
Prevalence of the initiator over the TATA box in human and yeast genes and identification of DNA motifs enriched in human TATA-less core promoters C Yang, E Bolotin, T Jiang, FM Sladek, E Martinez Gene 389 (1), 52-65, 2007 | 528 | 2007 |
A transcriptional hierarchy involved in mammalian cell-type specification CJ Kuo, PB Conley, L Chen, FM Sladek, JE Darnell Jr, GR Crabtree Nature 355 (6359), 457-461, 1992 | 513 | 1992 |
Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells M Mietus-Snyder, FΜ Sladek, GS Ginsburg, C Frank Kuo, JAA Ladias, ... Molecular and Cellular Biology 12 (4), 1708-1718, 1992 | 326 | 1992 |
Hepatocyte nuclear factor 4α orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver MA Battle, G Konopka, F Parviz, AL Gaggl, C Yang, FM Sladek, ... Proceedings of the National Academy of Sciences 103 (22), 8419-8424, 2006 | 312 | 2006 |
The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids. RK Hall, FM Sladek, DK Granner Proceedings of the National Academy of Sciences 92 (2), 412-416, 1995 | 282 | 1995 |
International union of pharmacology. LXVI. Orphan nuclear receptors G Benoit, A Cooney, V Giguere, H Ingraham, M Lazar, G Muscat, ... Pharmacological reviews 58 (4), 798-836, 2006 | 272 | 2006 |
Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptors G Jiang, L Nepomuceno, K Hopkins, FM Sladek Molecular and Cellular Biology 15 (9), 5131-5143, 1995 | 260 | 1995 |
Identification of an endogenous ligand bound to a native orphan nuclear receptor X Yuan, TC Ta, M Lin, JR Evans, Y Dong, E Bolotin, MA Sherman, ... PloS one 4 (5), e5609, 2009 | 245 | 2009 |
The concise guide to PHARMACOLOGY 2015/16: Overview SPH Alexander, E Kelly, N Marrion, JA Peters, HE Benson, E Faccenda, ... British journal of pharmacology 172 (24), 5729-5743, 2015 | 242 | 2015 |
AMP-activated protein kinase is involved in endothelial NO synthase activation in response to shear stress Y Zhang, TS Lee, EM Kolb, K Sun, X Lu, FM Sladek, GS Kassab, ... Arteriosclerosis, thrombosis, and vascular biology 26 (6), 1281-1287, 2006 | 233 | 2006 |
What are nuclear receptor ligands? FM Sladek Molecular and cellular endocrinology 334 (1-2), 3-13, 2011 | 217 | 2011 |
Hepatocyte nuclear factor 4α is essential for embryonic development of the mouse colon WD Garrison, MA Battle, C Yang, KH Kaestner, FM Sladek, SA Duncan Gastroenterology 130 (4), 19. e1-19. e, 2006 | 208 | 2006 |
The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription. KG Xanthopoulos, VR Prezioso, WS Chen, FM Sladek, R Cortese, ... Proceedings of the National Academy of Sciences 88 (9), 3807-3811, 1991 | 208 | 1991 |
Integrated approach for the identification of human hepatocyte nuclear factor 4α target genes using protein binding microarrays E Bolotin, H Liao, TC Ta, C Yang, W Hwang‐Verslues, JR Evans, T Jiang, ... Hepatology 51 (2), 642-653, 2010 | 199 | 2010 |
Hepatocyte nuclear factor-4α is essential for glucose-stimulated insulin secretion by pancreatic β-cells A Miura, K Yamagata, M Kakei, H Hatakeyama, N Takahashi, K Fukui, ... Journal of Biological Chemistry 281 (8), 5246-5257, 2006 | 199 | 2006 |
MAP kinase phosphorylation‐dependent activation of Elk‐1 leads to activation of the co‐activator p300 QJ Li, SH Yang, Y Maeda, FM Sladek, AD Sharrocks, M Martins‐Green The EMBO journal, 2003 | 192 | 2003 |
Modulation of transcriptional activation and coactivator interaction by a splicing variation in the F domain of nuclear receptor hepatocyte nuclear factor 4α1 FM Sladek, MD Ruse Jr, L Nepomuceno, SM Huang, MR Stallcup Molecular and cellular biology 19 (10), 6509-6522, 1999 | 178 | 1999 |
The expression pattern of a Drosophila homolog to the mouse transcription factor HNF‐4 suggests a determinative role in gut formation. W Zhong, FM Sladek, JE Darnell Jr The EMBO Journal 12 (2), 537-544, 1993 | 165 | 1993 |