The diabetes drug liraglutide prevents degenerative processes in a mouse model of Alzheimer's disease PL McClean, V Parthsarathy, E Faivre, C Hölscher Journal of Neuroscience 31 (17), 6587-6594, 2011 | 737 | 2011 |
Chronic treatment with the GLP1 analogue liraglutide increases cell proliferation and differentiation into neurons in an AD mouse model V Parthsarathy, C Hölscher PloS one 8 (3), e58784, 2013 | 139 | 2013 |
The type 2 diabetes drug liraglutide reduces chronic inflammation induced by irradiation in the mouse brain V Parthsarathy, C Hölscher European journal of pharmacology 700 (1-3), 42-50, 2013 | 134 | 2013 |
A novel retro-inverso peptide inhibitor reduces amyloid deposition, oxidation and inflammation and stimulates neurogenesis in the APPswe/PS1ΔE9 mouse model of Alzheimer’s disease V Parthsarathy, PL McClean, C Hölscher, M Taylor, C Tinker, G Jones, ... PloS one 8 (1), e54769, 2013 | 108 | 2013 |
Atlantic salmon (Salmo salar) co-product-derived protein hydrolysates: A source of antidiabetic peptides PA Harnedy, V Parthsarathy, CM McLaughlin, MB O'Keeffe, PJ Allsopp, ... Food Research International 106, 598-606, 2018 | 104 | 2018 |
Metabolic and neuroprotective effects of dapagliflozin and liraglutide in diabetic mice P Millar, N Pathak, V Parthsarathy, AJ Bjourson, M O’Kane, V Pathak, ... Journal of Endocrinology 234 (3), 255-267, 2017 | 72 | 2017 |
Blue whiting (Micromesistius poutassou) muscle protein hydrolysate with in vitro and in vivo antidiabetic properties PA Harnedy, V Parthsarathy, CM McLaughlin, MB O'Keeffe, PJ Allsopp, ... Journal of Functional Foods 40, 137-145, 2018 | 59 | 2018 |
Long-term treatment with acylated analogues of apelin-13 amide ameliorates diabetes and improves lipid profile of high-fat fed mice FPM O’Harte, V Parthsarathy, C Hogg, PR Flatt PLoS One 13 (8), e0202350, 2018 | 40 | 2018 |
Xenin-25[Lys13PAL]: a novel long-acting acylated analogue of xenin-25 with promising antidiabetic potential VA Gault, CMA Martin, PR Flatt, V Parthsarathy, N Irwin Acta Diabetologica 52, 461-471, 2015 | 38 | 2015 |
Characterisation of the biological activity of xenin-25 degradation fragment peptides CM Martin, V Parthsarathy, V Pathak, VA Gault, PR Flatt, N Irwin J Endocrinol 221 (2), 193-200, 2014 | 34 | 2014 |
Acylated apelin-13 amide analogues exhibit enzyme resistance and prolonged insulin releasing, glucose lowering and anorexic properties FPM O'Harte, V Parthsarathy, C Hogg, PR Flatt Biochemical pharmacology 146, 165-173, 2017 | 31 | 2017 |
An enzymatically stable GIP/xenin hybrid peptide restores GIP sensitivity, enhances beta cell function and improves glucose homeostasis in high-fat-fed mice A Hasib, MT Ng, VA Gault, D Khan, V Parthsarathy, PR Flatt, N Irwin Diabetologia 60, 541-552, 2017 | 30 | 2017 |
Apelin-13 analogues show potent in vitro and in vivo insulinotropic and glucose lowering actions FPM O’Harte, V Parthsarathy, C Hogg, PR Flatt Peptides 100, 219-228, 2018 | 29 | 2018 |
Biological activity and antidiabetic potential of C-terminal octapeptide fragments of the gut-derived hormone xenin CM Martin, V Parthsarathy, A Hasib, MT Ng, S McClean, PR Flatt, ... PLoS One 11 (3), e0152818, 2016 | 29 | 2016 |
A novel chemically modified analogue of xenin-25 exhibits improved glucose-lowering and insulin-releasing properties V Parthsarathy, N Irwin, A Hasib, CM Martin, S McClean, VK Bhat, MT Ng, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1860 (4), 757-764, 2016 | 28 | 2016 |
Exendin-4 stimulates autophagy in pancreatic β-cells via the RAPGEF/EPAC-Ca2+-PPP3/calcineurin-TFEB axis FP Zummo, SI Krishnanda, M Georgiou, FPM O’Harte, V Parthsarathy, ... Autophagy 18 (4), 799-815, 2022 | 25 | 2022 |
Boarfish (Capros aper) protein hydrolysate has potent insulinotropic and GLP‐1 secretory activity in vitro and acute glucose lowering effects in mice V Parthsarathy, CM McLaughlin, PA Harnedy, PJ Allsopp, W Crowe, ... International journal of food science & technology 54 (1), 271-281, 2019 | 24 | 2019 |
Beneficial long‐term antidiabetic actions of N‐and C‐terminally modified analogues of apelin‐13 in diet‐induced obese diabetic mice V Parthsarathy, C Hogg, PR Flatt, FPM O'Harte Diabetes, Obesity and Metabolism 20 (2), 319-327, 2018 | 24 | 2018 |
Twice daily oral administration of Palmaria palmata protein hydrolysate reduces food intake in streptozotocin induced diabetic mice, improving glycaemic control and lipid profiles CM McLaughlin, SJ Sharkey, P Harnedy-Rothwell, V Parthsarathy, ... Journal of Functional Foods 73, 104101, 2020 | 16 | 2020 |
Chronic apelin analogue administration is more effective than established incretin therapies for alleviating metabolic dysfunction in diabetic db/db mice FPM O'Harte, V Parthsarathy, PR Flatt Molecular and cellular endocrinology 504, 110695, 2020 | 14 | 2020 |