Paul I W de Bakker

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183 articles

7 articles

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Mark DalyDirector, Institute for Molecular Medicine Finland (FIMM) & Chief, ATGU, MGH & Broad InstituteAdresse e-mail validée de atgu.mgh.harvard.edu
Soumya RaychaudhuriHarvard Medical School; Brigham and Women's Hospital, Broad Institute, Univ of ManchesterAdresse e-mail validée de broadinstitute.org
Benjamin NealeAssociate Professor, Analytic and Translational Genetics Unit, Massachusetts General HospitalAdresse e-mail validée de broadinstitute.org
Shaun PurcellSleep & Neurogenetics Lab, Brigham & Women's Hospital, BostonAdresse e-mail validée de bwh.harvard.edu
Manuel A. R. FerreiraRegeneron PharmaceuticalsAdresse e-mail validée de regeneron.com
Sara L PulitVertex PharmaceuticalsAdresse e-mail validée de vrtx.com
Peter K. GregersenHead, Robert S. Boas Center for Genomics and Human GeneticsAdresse e-mail validée de nshs.edu
Cisca Wijmenga, PhDERC advanced investigator; Professor of Human Genetics, Dept Genetics (MGE), UMCG, Groningen, theAdresse e-mail validée de umcg.nl
Robert PlengeAdresse e-mail validée de partners.org
Simon LovellProfessor of Molecular Biology, University of ManchesterAdresse e-mail validée de manchester.ac.uk
Xiaoming JiaUCSF Medical CenterAdresse e-mail validée de ucsf.edu
Tom L BlundellEmeritus Professor of Biochemistry, University of CambridgeAdresse e-mail validée de cam.ac.uk
Shamil SunyaevProfessor of Biomedical Informatics and of Medicine (BWH), Harvard Medical SchoolAdresse e-mail validée de rics.bwh.harvard.edu
Mark DePristoBigHat BiosciencesAdresse e-mail validée de bighatbio.com
Richa SaxenaProfessor of Anaesthesia, Harvard Medical School, Massachusetts General HospitalAdresse e-mail validée de broadinstitute.org

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Paul I W de Bakker

Vertex Pharmaceuticals

Adresse e-mail validée de vrtx.com

human genetics computational genomics structural biology drug discovery bioinformatics


Titre Trier par citations Trier par année Trier par titre	Citée par Citée par	Année
PLINK: a tool set for whole-genome association and population-based linkage analyses S Purcell, B Neale, K Todd-Brown, L Thomas, MAR Ferreira, D Bender, ... The American journal of human genetics 81 (3), 559-575, 2007	28297	2007
A second generation human haplotype map of over 3.1 million SNPs. KA Frazer, DG Ballinger, DR Cox, DA Hinds, LL Stuve, RA Gibbs, ... Nature 449 (7164), 851-861, 2007	8976*	2007
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Management Group Liefer Laura A. 51 Wetterstrand Kris A. 51 Good Peter J. 51 ... nature 447 (7146), 799-816, 2007	5798	2007
Structure validation by Cα geometry: ϕ, ψ and Cβ deviation SC Lovell, IW Davis, WB Arendall III, PIW De Bakker, JM Word, ... Proteins: Structure, Function, and Bioinformatics 50 (3), 437-450, 2003	5184	2003
Genetic studies of body mass index yield new insights for obesity biology AE Locke, B Kahali, SI Berndt, AE Justice, TH Pers, FR Day, C Powell, ... Nature 518 (7538), 197-206, 2015	4083	2015
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels R Saxena, BF Voight, V Lyssenko, NP Burtt, PIW de Bakker, H Chen, ... Science 316 (5829), 1331-1336, 2007	2927	2007
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis Nature 476 (7359), 214-219, 2011	2762	2011
A reference panel of 64,976 haplotypes for genotype imputation Nature genetics 48 (10), 1279-1283, 2016	2383	2016
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study BF Voight, GM Peloso, M Orho-Melander, R Frikke-Schmidt, M Barbalic, ... The Lancet 380 (9841), 572-580, 2012	2352	2012
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes E Zeggini, LJ Scott, R Saxena, BF Voight, JL Marchini, T Hu, ... Nature genetics 40 (5), 638-645, 2008	2191	2008
Efficiency and power in genetic association studies PIW De Bakker, R Yelensky, I Pe'er, SB Gabriel, MJ Daly, D Altshuler Nature genetics 37 (11), 1217-1223, 2005	2044	2005
Genome-wide detection and characterization of positive selection in human populations PC Sabeti, P Varilly, B Fry, J Lohmueller, E Hostetter, C Cotsapas, X Xie, ... Nature 449 (7164), 913-918, 2007	2026	2007
Defining the role of common variation in the genomic and biological architecture of adult human height AR Wood, T Esko, J Yang, S Vedantam, TH Pers, S Gustafsson, AY Chu, ... Nature genetics 46 (11), 1173-1186, 2014	1932	2014
Common variants at 30 loci contribute to polygenic dyslipidemia S Kathiresan, CJ Willer, GM Peloso, S Demissie, K Musunuru, EE Schadt, ... Nature genetics 41 (1), 56-65, 2009	1499	2009
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci EA Stahl, S Raychaudhuri, EF Remmers, G Xie, S Eyre, BP Thomson, Y Li, ... Nature genetics 42 (6), 508-514, 2010	1487	2010
SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap AD Johnson, RE Handsaker, SL Pulit, MM Nizzari, CJ O'Donnell, ... Bioinformatics 24 (24), 2938-2939, 2008	1448	2008
STAT4 and the Risk of Rheumatoid Arthritis and Systemic Lupus Erythematosus EF Remmers, RM Plenge, AT Lee, RR Graham, G Hom, TW Behrens, ... New England Journal of Medicine 357 (10), 977-986, 2007	1241	2007
A haplotype map of the human genome D Altshuler Nature 437, 1299-1320, 2005	1157	2005
Integrated detection and population-genetic analysis of SNPs and copy number variation SA McCarroll, FG Kuruvilla, JM Korn, S Cawley, J Nemesh, A Wysoker, ... Nature genetics 40 (10), 1166-1174, 2008	1132	2008
TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program JC Florez, KA Jablonski, N Bayley, TI Pollin, PIW de Bakker, AR Shuldiner, ... New England Journal of Medicine 355 (3), 241-250, 2006	1073	2006

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