| Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating … P Godoy, NJ Hewitt, U Albrecht, ME Andersen, N Ansari, S Bhattacharya, ... Archives of toxicology 87, 1315-1530, 2013 | 1389 | 2013 |
| Identification of a tissue-selective heat shock response regulatory network E Guisbert, DM Czyz, K Richter, PD McMullen, RI Morimoto PLoS genetics 9 (4), e1003466, 2013 | 149 | 2013 |
| Applying'omics technologies in chemicals risk assessment: Report of an ECETOC workshop R Buesen, BN Chorley, B da Silva Lima, G Daston, L Deferme, T Ebbels, ... Regulatory Toxicology and Pharmacology 91, S3-S13, 2017 | 120 | 2017 |
| A map of the PPARα transcription regulatory network for primary human hepatocytes PD McMullen, S Bhattacharya, CG Woods, B Sun, K Yarborough, ... Chemico-biological interactions 209, 14-24, 2014 | 120 | 2014 |
| The human toxome project M Bouhifd, ME Andersen, C Baghdikian, K Boekelheide, KM Crofton, ... Altex 32 (2), 112, 2015 | 74 | 2015 |
| Modeling drug-and chemical-induced hepatotoxicity with systems biology approaches S Bhattacharya, LKM Shoda, Q Zhang, CG Woods, BA Howell, SQ Siler, ... Frontiers in physiology 3, 462, 2012 | 69 | 2012 |
| Profiling dose-dependent activation of p53-mediated signaling pathways by chemicals with distinct mechanisms of DNA damage RA Clewell, B Sun, Y Adeleye, P Carmichael, A Efremenko, PD McMullen, ... Toxicological sciences 142 (1), 56-73, 2014 | 56 | 2014 |
| Developing context appropriate toxicity testing approaches using new alternative methods (NAMs) ME Andersen, PD McMullen, MB Phillips, M Yoon, SN Pendse, ... ALTEX-Alternatives to animal experimentation 36 (4), 523-534, 2019 | 46 | 2019 |
| Macro-level Modeling of the Response of C. elegans Reproduction to Chronic Heat Stress PD McMullen, EZ Aprison, PB Winter, LAN Amaral, RI Morimoto, ... PLoS computational biology 8 (1), e1002338, 2012 | 41 | 2012 |
| Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays PD McMullen, ME Andersen, B Cholewa, HJ Clewell III, KM Dunnick, ... Toxicology in Vitro 48, 310-317, 2018 | 35 | 2018 |
| MYC is an early response regulator of human adipogenesis in adipose stem cells C Deisenroth, MB Black, S Pendse, L Pluta, SM Witherspoon, ... PLoS One 9 (12), e114133, 2014 | 30 | 2014 |
| Application of a combined aggregate exposure pathway and adverse outcome pathway (AEP-AOP) approach to inform a cumulative risk assessment: A case study with phthalates RA Clewell, JA Leonard, CI Nicolas, JL Campbell, M Yoon, AY Efremenko, ... Toxicology in vitro 66, 104855, 2020 | 26 | 2020 |
| Assessing molecular initiating events (MIEs), key events (KEs) and modulating factors (MFs) for styrene responses in mouse lungs using whole genome gene expression profiling … ME Andersen, G Cruzan, MB Black, SN Pendse, D Dodd, JS Bus, ... Toxicology and applied pharmacology 335, 28-40, 2017 | 26 | 2017 |
| Multiple receptors shape the estrogen response pathway and are critical considerations for the future of in vitro-based risk assessment efforts MM Miller, PD McMullen, ME Andersen, RA Clewell Critical reviews in toxicology 47 (7), 570-586, 2017 | 25 | 2017 |
| Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity SN Pendse, A Maertens, M Rosenberg, D Roy, RA Fasani, ... Archives of Toxicology 91, 1749-1762, 2017 | 25 | 2017 |
| Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver ME Andersen, MB Black, JL Campbell, SN Pendse, HJ Clewell III, ... Toxicology and Applied Pharmacology 332, 149-158, 2017 | 23 | 2017 |
| Identifying qualitative differences in PPARα signaling networks in human and rat hepatocytes and their significance for next generation chemical risk assessment methods PD McMullen, S Bhattacharya, CG Woods, SN Pendse, MT McBride, ... Toxicology in Vitro 64, 104463, 2020 | 20 | 2020 |
| Addressing systematic inconsistencies between in vitro and in vivo transcriptomic mode of action signatures PD McMullen, SN Pendse, MB Black, K Mansouri, S Haider, ME Andersen, ... Toxicology in Vitro 58, 1-12, 2019 | 19 | 2019 |
| A toxicogenomic approach for the risk assessment of the food contaminant acetamide R Nault, B Bals, F Teymouri, MB Black, ME Andersen, PD McMullen, ... Toxicology and applied pharmacology 388, 114872, 2020 | 18 | 2020 |
| Population life-course exposure to health effects model (PLETHEM): An R package for PBPK modeling SN Pendse, A Efremenko, CE Hack, M Moreau, P Mallick, M Dzierlenga, ... Computational Toxicology 13, 100115, 2020 | 18 | 2020 |
