| Mapping genomic loci implicates genes and synaptic biology in schizophrenia Nature 604 (7906), 502–508, 2022 | 1320 | 2022 |
| DISC1: structure, function, and therapeutic potential for major mental illness DC Soares, BC Carlyle, NJ Bradshaw, DJ Porteous ACS chemical neuroscience 2 (11), 609-632, 2011 | 160 | 2011 |
| A multiregional proteomic survey of the postnatal human brain BC Carlyle, RR Kitchen, JE Kanyo, EZ Voss, M Pletikos, AMM Sousa, ... Nature neuroscience 20 (12), 1787-1795, 2017 | 135 | 2017 |
| cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex BC Carlyle, AC Nairn, M Wang, Y Yang, LE Jin, AA Simen, BP Ramos, ... Proceedings of the National Academy of Sciences 111 (13), 5036-5041, 2014 | 128 | 2014 |
| DISC1, PDE4B, and NDE1 at the centrosome and synapse NJ Bradshaw, F Ogawa, B Antolin-Fontes, JE Chubb, BC Carlyle, ... Biochemical and biophysical research communications 377 (4), 1091-1096, 2008 | 108 | 2008 |
| The aged rhesus macaque manifests Braak stage III/IV Alzheimer's-like pathology CD Paspalas, BC Carlyle, S Leslie, TM Preuss, JL Crimins, AJ Huttner, ... Alzheimer's & Dementia 14 (5), 680-691, 2018 | 96 | 2018 |
| PKA phosphorylation of NDE1 is DISC1/PDE4 dependent and modulates its interaction with LIS1 and NDEL1 NJ Bradshaw, DC Soares, BC Carlyle, F Ogawa, H Davidson-Smith, ... Journal of Neuroscience 31 (24), 9043-9054, 2011 | 91 | 2011 |
| Maternal separation with early weaning: a rodent model providing novel insights into neglect associated developmental deficits BC Carlyle, A Duque, RR Kitchen, KA Bordner, D Coman, E Doolittle, ... Development and psychopathology 24 (4), 1401-1416, 2012 | 88 | 2012 |
| Functional genomic and proteomic analysis reveals disruption of myelin-related genes and translation in a mouse model of early life neglect KA Bordner, ED George, BC Carlyle, A Duque, RR Kitchen, TKT Lam, ... Frontiers in psychiatry 2, 18, 2011 | 74 | 2011 |
| Proteomic Approaches for the Discovery of Biofluid Biomarkers of Neurodegenerative Dementias B Carlyle, B Trombetta, S Arnold Proteomes 6 (3), 32, 2018 | 64 | 2018 |
| NDE1 and NDEL1: multimerisation, alternate splicing and DISC1 interaction NJ Bradshaw, S Christie, DC Soares, BC Carlyle, DJ Porteous, JK Millar Neuroscience letters 449 (3), 228-233, 2009 | 56 | 2009 |
| Plasma IL‐12/IFN‐γ axis predicts cognitive trajectories in cognitively unimpaired older adults HS Yang, C Zhang, BC Carlyle, SY Zhen, BA Trombetta, AP Schultz, ... Alzheimer's & Dementia 18 (4), 645-653, 2022 | 55 | 2022 |
| Cerebrovascular senescence is associated with tau pathology in Alzheimer's disease AG Bryant, M Hu, BC Carlyle, SE Arnold, MP Frosch, S Das, BT Hyman, ... Frontiers in neurology 11, 575953, 2020 | 54 | 2020 |
| Parallel declines in cognition, motivation, and locomotion in aging mice: association with immune gene upregulation in the medial prefrontal cortex KA Bordner, RR Kitchen, B Carlyle, ED George, MC Mahajan, SM Mane, ... Experimental gerontology 46 (8), 643-659, 2011 | 52 | 2011 |
| VGF as a biomarker and therapeutic target in neurodegenerative and psychiatric diseases JP Quinn, SE Kandigian, BA Trombetta, SE Arnold, BC Carlyle Brain Communications 3 (4), fcab261, 2021 | 46 | 2021 |
| Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease SM Vallabh, EV Minikel, VJ Williams, BC Carlyle, AJ McManus, ... BMC medicine 18, 1-12, 2020 | 46 | 2020 |
| Loss of Ftsj1 perturbs codon-specific translation efficiency in the brain and is associated with X-linked intellectual disability Y Nagayoshi, T Chujo, S Hirata, H Nakatsuka, CW Chen, M Takakura, ... Science Advances 7 (13), eabf3072, 2021 | 42 | 2021 |
| The technical reliability and biotemporal stability of cerebrospinal fluid biomarkers for profiling multiple pathophysiologies in Alzheimer’s disease BA Trombetta, BC Carlyle, AM Koenig, LM Shaw, JQ Trojanowski, ... PloS one 13 (3), e0193707, 2018 | 41 | 2018 |
| Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics BC Carlyle, SE Kandigian, J Kreuzer, S Das, BA Trombetta, Y Kuo, ... Neurobiology of aging 105, 99-114, 2021 | 38 | 2021 |
| Increased levels of the synaptic proteins PSD-95, SNAP-25, and neurogranin in the cerebrospinal fluid of patients with Alzheimer’s disease P Kivisäkk, BC Carlyle, T Sweeney, JP Quinn, CE Ramirez, BA Trombetta, ... Alzheimer's research & therapy 14 (1), 58, 2022 | 36 | 2022 |
Steven ArnoldProfessor of neurology, Harvard Medical SchoolVerified email at mgh.harvard.edu
