Irene Frischauf
Irene Frischauf
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Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation
M Muik, I Frischauf, I Derler, M Fahrner, J Bergsmann, P Eder, R Schindl, ...
Journal of Biological Chemistry 283 (12), 8014-8022, 2008
A cytosolic homomerization and a modulatory domain within STIM1 C terminus determine coupling to ORAI1 channels
M Muik, M Fahrner, I Derler, R Schindl, J Bergsmann, I Frischauf, ...
Journal of biological chemistry 284 (13), 8421-8426, 2009
Proliferation of aligned mammalian cells on laser-nanostructured polystyrene
E Rebollar, I Frischauf, M Olbrich, T Peterbauer, S Hering, J Preiner, ...
Biomaterials 29 (12), 1796-1806, 2008
STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation
M Muik, M Fahrner, R Schindl, P Stathopulos, I Frischauf, I Derler, P Plenk, ...
The EMBO journal 30 (9), 1678-1689, 2011
Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1–3 channels by a STIM1 coiled-coil mutant
I Frischauf, M Muik, I Derler, J Bergsmann, M Fahrner, R Schindl, ...
Journal of biological chemistry 284 (32), 21696-21706, 2009
2-aminoethoxydiphenyl borate alters selectivity of Orai3 channels by increasing their pore size
R Schindl, J Bergsmann, I Frischauf, I Derler, M Fahrner, M Muik, R Fritsch, ...
Journal of Biological Chemistry 283 (29), 20261-20267, 2008
The STIM/Orai coupling machinery
I Frischauf, R Schindl, I Derler, J Bergsmann, M Fahrner, C Romanin
Channels 2 (4), 261-268, 2008
Novel pyrazole compounds for pharmacological discrimination between receptor‐operated and store‐operated Ca2+ entry pathways
H Schleifer, B Doleschal, M Lichtenegger, R Oppenrieder, I Derler, ...
British journal of pharmacology 167 (8), 1712-1722, 2012
Mechanistic view on domains mediating STIM1–Orai coupling
M Fahrner, M Muik, I Derler, R Schindl, R Fritsch, I Frischauf, C Romanin
Immunological reviews 231 (1), 99-112, 2009
Mobile ionic impurities in poly (vinyl alcohol) gate dielectric: possible source of the hysteresis in organic field‐effect transistors
M Egginger, M Irimia‐Vladu, R Schwödiauer, A Tanda, I Frischauf, ...
Advanced materials 20 (5), 1018-1022, 2008
Resting state Orai1 diffuses as homotetramer in the plasma membrane of live mammalian cells
J Madl, J Weghuber, R Fritsch, I Derler, M Fahrner, I Frischauf, B Lackner, ...
Journal of Biological Chemistry 285 (52), 41135-41142, 2010
Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant
I Derler, M Fahrner, O Carugo, M Muik, J Bergsmann, R Schindl, ...
Journal of Biological Chemistry 284 (23), 15903-15915, 2009
Plasticity in Ca2+ selectivity of Orai1/Orai3 heteromeric channel
R Schindl, I Frischauf, J Bergsmann, M Muik, I Derler, B Lackner, ...
Proceedings of the National Academy of Sciences 106 (46), 19623-19628, 2009
Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription
I Frischauf, M Litviňuková, R Schober, V Zayats, B Svobodová, ...
Science signaling 10 (507), 2017
A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca2+ permeation and SOCE-induced gene transcription
I Frischauf, V Zayats, M Deix, A Hochreiter, I Jardin, M Muik, B Lackner, ...
Science signaling 8 (408), ra131-ra131, 2015
Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx
R Schindl, R Fritsch, I Jardin, I Frischauf, H Kahr, M Muik, MC Riedl, ...
Journal of Biological Chemistry 287 (42), 35612-35620, 2012
Cooperativeness of Orai cytosolic domains tunes subtype-specific gating
I Frischauf, R Schindl, J Bergsmann, I Derler, M Fahrner, M Muik, R Fritsch, ...
Journal of Biological Chemistry 286 (10), 8577-8584, 2011
The first ankyrin-like repeat is the minimum indispensable key structure for functional assembly of homo-and heteromeric TRPC4/TRPC5 channels
R Schindl, I Frischauf, H Kahr, R Fritsch, M Krenn, A Derndl, E Vales, ...
Cell calcium 43 (3), 260-269, 2008
Molecular determinants within N terminus of Orai3 protein that control channel activation and gating
J Bergsmann, I Derler, M Muik, I Frischauf, M Fahrner, P Pollheimer, ...
Journal of Biological Chemistry 286 (36), 31565-31575, 2011
EUV micropatterning for biocompatibility control of PET
B Reisinger, M Fahrner, I Frischauf, S Yakunin, V Svorcik, H Fiedorowicz, ...
Applied Physics A 100 (2), 511-516, 2010
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