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Felipe de Souza Leite, Ph.D.
Felipe de Souza Leite, Ph.D.
Senior Scientist at the Boston Children's Hospital | Harvard Medical School
Geverifieerd e-mailadres voor mail.mcgill.ca - Homepage
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Effects of controlled mechanical ventilation on sepsis-induced diaphragm dysfunction in rats
K Maes, A Stamiris, D Thomas, N Cielen, A Smuder, SK Powers, FS Leite, ...
Critical Care Medicine 42 (12), e772-e782, 2014
722014
Prolonged controlled mechanical ventilation in humans triggers myofibrillar contractile dysfunction and myofilament protein loss in the diaphragm
SNA Hussain, AS Cornachione, C Guichon, A Al Khunaizi, ...
Thorax 71 (5), 436-445, 2016
692016
The increase in non-cross-bridge forces after stretch of activated striated muscle is related to titin isoforms
AS Cornachione, F Leite, MA Bagni, DE Rassier
American Journal of Physiology-Cell Physiology 310 (1), C19-C26, 2016
692016
Residual force enhancement is regulated by titin in skeletal and cardiac myofibrils
N Shalabi, A Cornachione, F Leite, S Vengallatore, DE Rassier
Journal of Physiology, 2016
482016
Prolonged force depression after mechanically demanding contractions is largely independent of Ca2+ and reactive oxygen species
S Kamandulis, F de Souza Leite, A Hernández, A Katz, M Brazaitis, ...
The FASEB Journal 31 (11), 4809-4820, 2017
372017
Non-crossbridge forces in activated striated muscles: a titin dependent mechanism of regulation?
DE Rassier, FS Leite, M Nocella, AS Cornachione, B Colombini, ...
Journal of muscle research and cell motility 36, 37-45, 2015
342015
Arginylation of myosin heavy chain regulates skeletal muscle strength
AS Cornachione, FS Leite, J Wang, NA Leu, A Kalganov, D Volgin, X Han, ...
Cell reports 8 (2), 470-476, 2014
342014
Sarcomere length nonuniformity and force regulation in myofibrils and sarcomeres
F de Souza Leite, DE Rassier
Biophysical Journal 119 (12), 2372-2377, 2020
242020
Reduced passive force in skeletal muscles lacking protein arginylation
FS Leite, FC Minozzo, A Kalganov, AS Cornachione, YS Cheng, NA Leu, ...
American Journal of Physiology-Cell Physiology 310 (2), C127-C135, 2016
212016
Microfluidic perfusion shows intersarcomere dynamics within single skeletal muscle myofibrils
F de Souza Leite, FC Minozzo, D Altman, D Rassier
Proceedings of the National Academy of Sciences of the United States of …, 2017
202017
Different gene expression profiles in iPSC-derived motor neurons from ALS8 patients with variable clinical courses suggest mitigating pathways for neurodegeneration
D Oliveira, DA Morales-Vicente, MS Amaral, L Luz, AL Sertié, FS Leite, ...
Human molecular genetics 29 (9), 1465-1475, 2020
132020
The load dependence and the force-velocity relation in intact myosin filaments from skeletal and smooth muscles
YS Cheng, F de Souza Leite, DE Rassier
American Journal of Physiology-Cell Physiology 318 (1), C103-C110, 2020
132020
Sarcomere length non-uniformities dictate force production along the descending limb of the force–length relation
R Haeger, F de Souza Leite, DE Rassier
Proceedings of the Royal Society B 287 (1937), 20202133, 2020
112020
Clinical aspects of hereditary spastic paraplegia 76 and novel CAPN1 mutations.
US Melo, F Freua, DS Lynch, BD Ripa, RB Tenorio, JAM Saute, ...
Clinical Genetics 94 (5), 2018
102018
Posttranslational arginylation regulates striated muscle function
F de Souza Leite, A Kashina, DE Rassier
Exercise and Sport Sciences Reviews 44 (3), 98-103, 2016
102016
A fast method to reprogram and CRISPR/Cas9 gene editing from erythroblasts
US Melo, F de Souza Leite, S Costa, C Rosenberg, M Zatz
Stem Cell Research 31, 52-54, 2018
82018
Residual force depression in single sarcomeres is abolished by MgADP-induced activation
N Trecarten, FC Minozzo, FS Leite, DE Rassier
Scientific Reports 5 (1), 10555, 2015
62015
Biallelic UBE4A loss-of-function variants cause intellectual disability and global developmental delay
US Melo, D Bonner, KC Kent Lloyd, A Moshiri, B Willis, L Lanoue, ...
Genetics in Medicine 23 (4), 661-668, 2021
32021
Shortening-induced force depression in single sarcomeres is abolished by MgADP-activation
N Trecarten, FC Minozzo, FS Leite, DE Rassier
Biophysical Journal 108 (2), 338a, 2015
12015
Prolonged Mechanical Ventilation In Humans Triggers Myofilament Contractile Dysfunction And Selective Myofilament Protein Degradation In The Diaphragm
C Guichon, A Al Khunaizi, F De Souza Leite, A Cornachione, M Mofarrahi, ...
D97. ICU ACQUIRED MUSCLE WEAKNESS: MECHANISMS, DIAGNOSIS, AND TREATMENT …, 2014
12014
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Artikelen 1–20