| Aminoacylation of RNA minihelices with alanine C Francklyn, P Schimmel Nature 337 (6206), 478-481, 1989 | 381 | 1989 |
| Chemical synthesis of biologically active oligoribonucleotides using β-cyanoethyl protected ribonucleoside phosphoramidites SA Scaringe, C Francklyn, N Usman Nucleic acids research 18 (18), 5433-5441, 1990 | 378 | 1990 |
| Genetic mapping and exome sequencing identify variants associated with five novel diseases EG Puffenberger, RN Jinks, C Sougnez, K Cibulskis, RA Willert, ... PloS one 7 (1), e28936, 2012 | 352 | 2012 |
| Transfer RNA–mediated editing in threonyl-tRNA synthetase: the class II solution to the double discrimination problem AC Dock-Bregeon, R Sankaranarayanan, P Romby, J Caillet, M Springer, ... Cell 103 (6), 877-884, 2000 | 235 | 2000 |
| Transfer RNA and human disease JA Abbott, CS Francklyn, SM Robey-Bond Frontiers in genetics 5, 93032, 2014 | 221 | 2014 |
| Arabinose-induced binding of AraC protein to araI2 activates the araBAD operon promoter. N Lee, C Francklyn, EP Hamilton Proceedings of the National Academy of Sciences 84 (24), 8814-8818, 1987 | 200 | 1987 |
| Zinc ion mediated amino acid discrimination by threonyl-tRNA synthetase R Sankaranarayanan, AC Dock-Bregeon, B Rees, M Bovee, J Caillet, ... Nature structural biology 7 (6), 461-465, 2000 | 192 | 2000 |
| Crystal structure of histidyl‐tRNA synthetase from Escherichia coli complexed with histidyl‐adenylate. JG Arnez, DC Harris, A Mitschler, B Rees, CS Francklyn, D Moras The EMBO journal 14 (17), 4143-4155, 1995 | 180 | 1995 |
| An aminoacyl-tRNA synthetase paralog with a catalytic role in histidine biosynthesis M Sissler, C Delorme, J Bond, SD Ehrlich, P Renault, C Francklyn Proceedings of the National Academy of Sciences 96 (16), 8985-8990, 1999 | 168 | 1999 |
| Enzymatic aminoacylation of an eight-base-pair microhelix with histidine. C Francklyn, P Schimmel Proceedings of the National Academy of Sciences 87 (21), 8655-8659, 1990 | 162 | 1990 |
| Overlapping nucleotide determinants for specific aminoacylation of RNA microhelices C Francklyn, JP Shi, P Schimmel Science 255 (5048), 1121-1125, 1992 | 159 | 1992 |
| Methods for kinetic and thermodynamic analysis of aminoacyl-tRNA synthetases CS Francklyn, EA First, JJ Perona, YM Hou Methods 44 (2), 100-118, 2008 | 153 | 2008 |
| Distinct kinetic mechanisms of the two classes of aminoacyl-tRNA synthetases CM Zhang, JJ Perona, K Ryu, C Francklyn, YM Hou Journal of molecular biology 361 (2), 300-311, 2006 | 142 | 2006 |
| The tRNA‐binding moiety in GCN2 contains a dimerization domain that interacts with the kinase domain and is required for tRNA binding and kinase activation H Qiu, J Dong, C Hu, CS Francklyn, AG Hinnebusch The EMBO journal, 2001 | 130 | 2001 |
| The first step of aminoacylation at the atomic level in histidyl-tRNA synthetase JG Arnez, JG Augustine, D Moras, CS Francklyn Proceedings of the National Academy of Sciences 94 (14), 7144-7149, 1997 | 125 | 1997 |
| Aminoacyl-tRNA synthetases: versatile players in the changing theater of translation C Francklyn, JJ Perona, J Puetz, YM Hou Rna 8 (11), 1363-1372, 2002 | 124 | 2002 |
| The aminoacyl-tRNA synthetases M Ibba, C Francklyn, S Cusack (No Title), 2005 | 122 | 2005 |
| Progress and challenges in aminoacyl-tRNA synthetase-based therapeutics CS Francklyn, P Mullen Journal of Biological Chemistry 294 (14), 5365-5385, 2019 | 114 | 2019 |
| Standardizing analysis of circulating microRNA: clinical and biological relevance NH Farina, ME Wood, SD Perrapato, CS Francklyn, GS Stein, JL Stein, ... Journal of cellular biochemistry 115 (5), 805-811, 2014 | 110 | 2014 |
| Secreted Threonyl-tRNA synthetase stimulates endothelial cell migration and angiogenesis TF Williams, AC Mirando, B Wilkinson, CS Francklyn, KM Lounsbury Scientific reports 3 (1), 1317, 2013 | 108 | 2013 |
