The role of macrophage phenotype in vascularization of tissue engineering scaffolds KL Spiller, RR Anfang, KJ Spiller, J Ng, KR Nakazawa, JW Daulton, ... Biomaterials 35 (15), 4477-4488, 2014 | 911 | 2014 |
Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration A Kaplan, KJ Spiller, C Towne, KC Kanning, GT Choe, A Geber, T Akay, ... Neuron 81 (2), 333-348, 2014 | 313 | 2014 |
Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy KJ Spiller, CR Restrepo, T Khan, MA Dominique, TC Fang, RG Canter, ... Nature neuroscience 21 (3), 329-340, 2018 | 254 | 2018 |
Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43 AK Walker, KJ Spiller, G Ge, A Zheng, Y Xu, M Zhou, K Tripathy, ... Acta neuropathologica 130, 643-660, 2015 | 253 | 2015 |
Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats ZX Xi, K Spiller, AC Pak, J Gilbert, C Dillon, X Li, XQ Peng, EL Gardner Neuropsychopharmacology 33 (7), 1735-1745, 2008 | 117 | 2008 |
The selective dopamine D3 receptor antagonists SB-277011A and NGB 2904 and the putative partial D3 receptor agonist BP-897 attenuate methamphetamine … K Spiller, ZX Xi, XQ Peng, AH Newman, CR Ashby, C Heidbreder, J Gaál, ... Psychopharmacology 196, 533-542, 2008 | 82 | 2008 |
Selective motor neuron resistance and recovery in a new inducible mouse model of TDP-43 proteinopathy KJ Spiller, CJ Cheung, CR Restrepo, LK Kwong, AM Stieber, ... Journal of Neuroscience 36 (29), 7707-7717, 2016 | 78 | 2016 |
Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism X Li, J Li, XQ Peng, K Spiller, EL Gardner, ZX Xi Neuropsychopharmacology 34 (7), 1783-1796, 2009 | 74 | 2009 |
Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats ZX Xi, Z Yang, SJ Li, X Li, C Dillon, XQ Peng, K Spiller, EL Gardner Neuropharmacology 53 (6), 771-782, 2007 | 72 | 2007 |
PG01037, a novel dopamine D3 receptor antagonist, inhibits the effects of methamphetamine in rats AE Higley, K Spiller, P Grundt, AH Newman, SW Kiefer, ZX Xi, EL Gardner Journal of psychopharmacology 25 (2), 263-273, 2011 | 71 | 2011 |
Cannabinoid CB1 and CB2 receptor mechanisms underlie cannabis reward and aversion in rats KJ Spiller, G Bi, Y He, E Galaj, EL Gardner, ZX Xi British journal of pharmacology 176 (9), 1268-1281, 2019 | 70 | 2019 |
Varenicline attenuates nicotine-enhanced brain-stimulation reward by activation of α4β2 nicotinic receptors in rats K Spiller, ZX Xi, X Li, CR Ashby Jr, PM Callahan, A Tehim, EL Gardner Neuropharmacology 57 (1), 60-66, 2009 | 67 | 2009 |
Mechanism-based medication development for the treatment of nicotine dependence Z Xi, K Spiller, EL Gardner Acta Pharmacologica Sinica 30 (6), 723-739, 2009 | 62 | 2009 |
The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats XQ Peng, CR Ashby Jr, K Spiller, X Li, J Li, N Thomasson, MJ Millan, ... Neuropharmacology 56 (4), 752-760, 2009 | 58 | 2009 |
N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaine-enhanced brain-stimulation reward in rats ZX Xi, M Kiyatkin, X Li, XQ Peng, A Wiggins, K Spiller, J Li, EL Gardner Neuropharmacology 58 (1), 304-313, 2010 | 51 | 2010 |
A stem cell-based screening platform identifies compounds that desensitize motor neurons to endoplasmic reticulum stress S Thams, ER Lowry, MH Larraufie, KJ Spiller, H Li, DJ Williams, P Hoang, ... Molecular Therapy 27 (1), 87-101, 2019 | 45 | 2019 |
Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications XQ Peng, ZX Xi, X Li, K Spiller, J Li, L Chun, KM Wu, M Froimowitz, ... Neuropsychopharmacology 35 (13), 2564-2578, 2010 | 35 | 2010 |
Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice KJ Spiller, T Khan, MA Dominique, CR Restrepo, D Cotton-Samuel, ... Neurobiology of disease 124, 133-140, 2019 | 33 | 2019 |
Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery M Hunter, KJ Spiller, MA Dominique, H Xu, FW Hunter, TC Fang, ... Acta Neuropathologica Communications 9, 1-19, 2021 | 31 | 2021 |
Progression of motor neuron disease is accelerated and the ability to recover is compromised with advanced age in rNLS8 mice KJ Spiller, CR Restrepo, T Khan, AM Stieber, LK Kwong, JQ Trojanowski, ... Acta neuropathologica communications 4, 1-11, 2016 | 17 | 2016 |