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Krista J. Spiller, Ph.D.
Krista J. Spiller, Ph.D.
Neuroscience Discovery, Janssen R&D
Verified email at its.jnj.com
Title
Cited by
Cited by
Year
The role of macrophage phenotype in vascularization of tissue engineering scaffolds
KL Spiller, RR Anfang, KJ Spiller, J Ng, KR Nakazawa, JW Daulton, ...
Biomaterials 35 (15), 4477-4488, 2014
9112014
Neuronal matrix metalloproteinase-9 is a determinant of selective neurodegeneration
A Kaplan, KJ Spiller, C Towne, KC Kanning, GT Choe, A Geber, T Akay, ...
Neuron 81 (2), 333-348, 2014
3132014
Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy
KJ Spiller, CR Restrepo, T Khan, MA Dominique, TC Fang, RG Canter, ...
Nature neuroscience 21 (3), 329-340, 2018
2542018
Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43
AK Walker, KJ Spiller, G Ge, A Zheng, Y Xu, M Zhou, K Tripathy, ...
Acta neuropathologica 130, 643-660, 2015
2532015
Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats
ZX Xi, K Spiller, AC Pak, J Gilbert, C Dillon, X Li, XQ Peng, EL Gardner
Neuropsychopharmacology 33 (7), 1735-1745, 2008
1172008
The selective dopamine D3 receptor antagonists SB-277011A and NGB 2904 and the putative partial D3 receptor agonist BP-897 attenuate methamphetamine …
K Spiller, ZX Xi, XQ Peng, AH Newman, CR Ashby, C Heidbreder, J Gaál, ...
Psychopharmacology 196, 533-542, 2008
822008
Selective motor neuron resistance and recovery in a new inducible mouse model of TDP-43 proteinopathy
KJ Spiller, CJ Cheung, CR Restrepo, LK Kwong, AM Stieber, ...
Journal of Neuroscience 36 (29), 7707-7717, 2016
782016
Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism
X Li, J Li, XQ Peng, K Spiller, EL Gardner, ZX Xi
Neuropsychopharmacology 34 (7), 1783-1796, 2009
742009
Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats
ZX Xi, Z Yang, SJ Li, X Li, C Dillon, XQ Peng, K Spiller, EL Gardner
Neuropharmacology 53 (6), 771-782, 2007
722007
PG01037, a novel dopamine D3 receptor antagonist, inhibits the effects of methamphetamine in rats
AE Higley, K Spiller, P Grundt, AH Newman, SW Kiefer, ZX Xi, EL Gardner
Journal of psychopharmacology 25 (2), 263-273, 2011
712011
Cannabinoid CB1 and CB2 receptor mechanisms underlie cannabis reward and aversion in rats
KJ Spiller, G Bi, Y He, E Galaj, EL Gardner, ZX Xi
British journal of pharmacology 176 (9), 1268-1281, 2019
702019
Varenicline attenuates nicotine-enhanced brain-stimulation reward by activation of α4β2 nicotinic receptors in rats
K Spiller, ZX Xi, X Li, CR Ashby Jr, PM Callahan, A Tehim, EL Gardner
Neuropharmacology 57 (1), 60-66, 2009
672009
Mechanism-based medication development for the treatment of nicotine dependence
Z Xi, K Spiller, EL Gardner
Acta Pharmacologica Sinica 30 (6), 723-739, 2009
622009
The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats
XQ Peng, CR Ashby Jr, K Spiller, X Li, J Li, N Thomasson, MJ Millan, ...
Neuropharmacology 56 (4), 752-760, 2009
582009
N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaine-enhanced brain-stimulation reward in rats
ZX Xi, M Kiyatkin, X Li, XQ Peng, A Wiggins, K Spiller, J Li, EL Gardner
Neuropharmacology 58 (1), 304-313, 2010
512010
A stem cell-based screening platform identifies compounds that desensitize motor neurons to endoplasmic reticulum stress
S Thams, ER Lowry, MH Larraufie, KJ Spiller, H Li, DJ Williams, P Hoang, ...
Molecular Therapy 27 (1), 87-101, 2019
452019
Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications
XQ Peng, ZX Xi, X Li, K Spiller, J Li, L Chun, KM Wu, M Froimowitz, ...
Neuropsychopharmacology 35 (13), 2564-2578, 2010
352010
Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice
KJ Spiller, T Khan, MA Dominique, CR Restrepo, D Cotton-Samuel, ...
Neurobiology of disease 124, 133-140, 2019
332019
Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery
M Hunter, KJ Spiller, MA Dominique, H Xu, FW Hunter, TC Fang, ...
Acta Neuropathologica Communications 9, 1-19, 2021
312021
Progression of motor neuron disease is accelerated and the ability to recover is compromised with advanced age in rNLS8 mice
KJ Spiller, CR Restrepo, T Khan, AM Stieber, LK Kwong, JQ Trojanowski, ...
Acta neuropathologica communications 4, 1-11, 2016
172016
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Articles 1–20