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J. Andrew N. Alexander
J. Andrew N. Alexander
Verified email at mol.biol.ethz.ch
Title
Cited by
Cited by
Year
High-level resistance of Staphylococcus aureus to β-lactam antibiotics mediated by penicillin-binding protein 4 (PBP4)
SM Hamilton, JAN Alexander, EJ Choo, L Basuino, TM da Costa, ...
Antimicrobial agents and chemotherapy 61 (6), 10.1128/aac. 02727-16, 2017
742017
Structural and kinetic characterization of diazabicyclooctanes as dual inhibitors of both serine-β-lactamases and penicillin-binding proteins
AM King, DT King, S French, E Brouillette, A Asli, JAN Alexander, ...
ACS chemical biology 11 (4), 864-868, 2016
652016
Structural and kinetic analysis of penicillin-binding protein 4 (PBP4)-mediated antibiotic resistance in Staphylococcus aureus
JAN Alexander, SS Chatterjee, SM Hamilton, LD Eltis, HF Chambers, ...
Journal of Biological Chemistry, 2018
542018
Recognition of peptidoglycan fragments by the transpeptidase PBP4 from Staphylococcus aureus
R Maya-Martinez, JA Alexander, C Otten, I Ayala, D Vollmer, C Bougault, ...
Frontiers in microbiology, 2019
312019
PBP4 activity and its overexpression are necessary for PBP4-mediated high-level β-lactam resistance
L Basuino, A Jousselin, JAN Alexander, NCJ Strynadka, MG Pinho, ...
Journal of Antimicrobial Chemotherapy 73 (5), 1177-1180, 2018
242018
Derivation of a continuous myogenic cell culture from an embryo of common killifish, Fundulus heteroclitus
SJ Gignac, NTK Vo, MS Mikhaeil, JAN Alexander, DL MacLatchy, ...
Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2014
242014
Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus
JAN Alexander, LJ Worrall, J Hu, M Vuckovic, N Satishkumar, R Poon, ...
Nature 613 (7943), 375-382, 2023
142023
Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
N Zeytuni, SW Dickey, J Hu, HT Chou, LJ Worrall, JAN Alexander, ...
Science advances 6 (40), eabb8219, 2020
132020
Emerging structural insights into C-type glycosyltransferases
JAN Alexander, KP Locher
Current Opinion in Structural Biology 79, 102547, 2023
112023
Structural analysis of avibactam-mediated activation of the bla and mec divergons in methicillin-resistant Staphylococcus aureus
JAN Alexander, M Radaeva, DT King, HF Chambers, A Cherkasov, ...
Journal of Biological Chemistry 295 (32), 10870-10884, 2020
102020
PBP4-mediated β-lactam resistance among clinical strains of Staphylococcus aureus
N Satishkumar, JAN Alexander, R Poon, E Buggeln, MA Argudín, ...
Journal of Antimicrobial Chemotherapy 76 (9), 2268-2272, 2021
52021
Development of a continuous cell line from larval Atlantic cod (Gadus morhua) and its use in the study of the microsporidian, Loma morhua
MJ MacLeod, NTK Vo, MS Mikhaeil, SR Monaghan, JAN Alexander, ...
Journal of fish diseases 41 (9), 1359-1372, 2018
32018
Synthesis and characterisation of fluorescent substrates for eukaryotic protein N-glycosylation
MM de Capitani, AS Ramírez, L Rossi, JAN Alexander, S De Lorenzo, ...
Tetrahedron 136, 133361, 2023
12023
Understanding Staphylococcus aureus β-lactam resistance: a structural investigation
JAN Alexander
University of British Columbia, 2020
2020
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