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Marc D Ruben
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A database of tissue-specific rhythmically expressed human genes has potential applications in circadian medicine
MD Ruben, G Wu, DF Smith, RE Schmidt, LJ Francey, YY Lee, RC Anafi, ...
Science Translational Medicine 10 (458), eaat8806, 2018
2572018
Guidelines for genome-scale analysis of biological rhythms
ME Hughes, KC Abruzzi, R Allada, R Anafi, AB Arpat, G Asher, P Baldi, ...
Journal of biological rhythms 32 (5), 380-393, 2017
2282017
Dosing time matters
MD Ruben, DF Smith, GF FitzGerald, JB Hogenesch
Science 365 (6453), 547-549, 2019
1882019
Population-level rhythms in human skin with implications for circadian medicine
G Wu, MD Ruben, RE Schmidt, LJ Francey, DF Smith, RC Anafi, ...
Proceedings of the National Academy of Sciences 115 (48), 12313-12318, 2018
1142018
Single-cell gene expression analysis: implications for neurodegenerative and neuropsychiatric disorders
SD Ginsberg, I Elarova, M Ruben, F Tan, SE Counts, JH Eberwine, ...
Neurochemical Research 29, 1053-1064, 2004
1082004
A mechanism for circadian control of pacemaker neuron excitability
M Ruben, MD Drapeau, D Mizrak, J Blau
Journal of biological rhythms 27 (5), 353-364, 2012
582012
Electrical activity can impose time of day on the circadian transcriptome of pacemaker neurons
D Mizrak, M Ruben, GN Myers, K Rhrissorrakrai, KC Gunsalus, J Blau
Current Biology 22 (20), 1871-1880, 2012
552012
Drosophila pacemaker neurons require g protein signaling and GABAergic inputs to generate twenty-four hour behavioral rhythms
D Dahdal, DC Reeves, M Ruben, MH Akabas, J Blau
Neuron 68 (5), 964-977, 2010
512010
A population-based gene expression signature of molecular clock phase from a single epidermal sample
G Wu, MD Ruben, LJ Francey, DF Smith, JD Sherrill, JE Oblong, KJ Mills, ...
Genome medicine 12, 1-12, 2020
422020
A large-scale study reveals 24-h operational rhythms in hospital treatment
MD Ruben, LJ Francey, Y Guo, G Wu, EB Cooper, AS Shah, ...
Proceedings of the National Academy of Sciences 116 (42), 20953-20958, 2019
282019
Circadian dysregulation: the next frontier in obstructive sleep apnea research
DC von Allmen, LJ Francey, GM Rogers, MD Ruben, AP Cohen, G Wu, ...
Otolaryngology–Head and Neck Surgery 159 (6), 948-955, 2018
282018
Short-term exposure to intermittent hypoxia leads to changes in gene expression seen in chronic pulmonary disease
G Wu, YY Lee, EM Gulla, A Potter, J Kitzmiller, MD Ruben, N Salomonis, ...
Elife 10, e63003, 2021
262021
Normalized coefficient of variation (nCV): a method to evaluate circadian clock robustness in population scale data
G Wu, LJ Francey, MD Ruben, JB Hogenesch
Bioinformatics 37 (23), 4581-4583, 2021
142021
Sleep and circadian medicine: time of day in the neurologic clinic
MD Ruben, JB Hogenesch, DF Smith
Neurologic clinics 37 (3), 615-629, 2019
132019
Genome-wide studies of time of day in the brain: Design and analysis
G Wu, MD Ruben, Y Lee, J Li, ME Hughes, JB Hogenesch
Brain Science Advances 6 (2), 92-105, 2020
122020
When should you take your medicines?
DF Smith, MD Ruben, LJ Francey, OJ Walch, JB Hogenesch
Journal of biological rhythms 34 (6), 582-583, 2019
122019
What is there left to learn about the Drosophila clock?
J Blau, F Blanchard, B Collins, D Dahdal, A Knowles, D Mizrak, M Ruben
Cold Spring Harbor symposia on quantitative biology 72, 243-250, 2007
112007
Circadian rhythms: move over neurons—astrocytes mediate SCN clock function
MD Ruben, JB Hogenesch
Current Biology 27 (9), R350-R352, 2017
92017
An in silico genome-wide screen for circadian clock strength in human samples
G Wu, MD Ruben, LJ Francey, YY Lee, RC Anafi, JB Hogenesch
Bioinformatics 38 (24), 5375-5382, 2022
82022
Intermittent hypoxia alters the circadian expression of clock genes in mouse brain and liver
BSC Koritala, YY Lee, SS Bhadri, LS Gaspar, C Stanforth, G Wu, ...
Genes 12 (10), 1627, 2021
82021
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