Gyan P. Srivastava
Gyan P. Srivastava
Foundational Neuroscience Center, AbbVie Inc.
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Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
PL De Jager, G Srivastava, K Lunnon, J Burgess, LC Schalkwyk, L Yu, ...
Nature neuroscience 17 (9), 1156-1163, 2014
Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes
T Raj, K Rothamel, S Mostafavi, C Ye, MN Lee, JM Replogle, T Feng, ...
Science 344 (6183), 519-523, 2014
Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
K Lunnon, R Smith, E Hannon, PL De Jager, G Srivastava, M Volta, ...
Nature neuroscience 17 (9), 1164-1170, 2014
Association of Brain DNA methylation in SORL1, ABCA7, HLA-DRB5, SLC24A4, and BIN1 with pathological diagnosis of Alzheimer disease
L Yu, LB Chibnik, GP Srivastava, N Pochet, J Yang, J Xu, J Kozubek, ...
JAMA neurology 72 (1), 15-24, 2015
The major risk factors for Alzheimer’s disease: age, sex, and genes modulate the microglia response to Aβ plaques
CS Frigerio, L Wolfs, N Fattorelli, N Thrupp, I Voytyuk, I Schmidt, ...
Cell reports 27 (4), 1293-1306. e6, 2019
Epigenomics of Alzheimer’s disease
DA Bennett, L Yu, J Yang, HU Klein, PL De Jager
Translating Epigenetics to the Clinic, 227-278, 2017
24-hour rhythms of DNA methylation and their relation with rhythms of RNA expression in the human dorsolateral prefrontal cortex
ASP Lim, GP Srivastava, L Yu, LB Chibnik, J Xu, AS Buchman, ...
PLoS Genet 10 (11), e1004792, 2014
Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing
EJ Lee, L Pei, G Srivastava, T Joshi, G Kushwaha, JH Choi, ...
Nucleic acids research 39 (19), e127-e127, 2011
Wingless directly represses DPP morphogen expression via an armadillo/TCF/Brinker complex
H Theisen, A Syed, BT Nguyen, T Lukacsovich, J Purcell, GP Srivastava, ...
PloS one 2 (1), e142, 2007
Alzheimer's loci: epigenetic associations and interaction with genetic factors
LB Chibnik, L Yu, ML Eaton, G Srivastava, JA Schneider, M Kellis, ...
Annals of clinical and translational neurology 2 (6), 636-647, 2015
5′RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy
DC Christodoulou, H Wakimoto, K Onoue, S Eminaga, JM Gorham, ...
The Journal of clinical investigation 124 (3), 1364-1370, 2014
A link between SIN1 (MAPKAP1) and poly (rC) binding protein 2 (PCBP2) in counteracting environmental stress
D Ghosh, GP Srivastava, D Xu, LC Schulz, RM Roberts
Proceedings of the National Academy of Sciences 105 (33), 11673-11678, 2008
Association of DNA methylation in the brain with age in older persons is confounded by common neuropathologies
J Yang, L Yu, C Gaiteri, GP Srivastava, LB Chibnik, SE Leurgans, ...
The international journal of biochemistry & cell biology 67, 58-64, 2015
PRIMEGENS-v2: genome-wide primer design for analyzing DNA methylation patterns of CpG islands
GP Srivastava, J Guo, H Shi, D Xu
Bioinformatics 24 (17), 1837-1842, 2008
A 17q12 allele is associated with altered NK cell subsets and function
Z Xia, Q Liu, CT Berger, BT Keenan, A Kaliszewska, PC Cheney, ...
The Journal of Immunology 188 (7), 3315-3322, 2012
Homolog-specific PCR primer design for profiling splice variants
GP Srivastava, M Hanumappa, G Kushwaha, HT Nguyen, D Xu
Nucleic acids research 39 (10), e69-e69, 2011
Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models
YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ...
Cell reports 32 (2), 107908, 2020
The Role of MAPT Haplotype H2 and Isoform 1N/4R in Parkinsonism of Older Adults
GT Valenca, GP Srivastava, J Oliveira-Filho, CC White, L Yu, ...
PloS one 11 (7), e0157452, 2016
Genome-scale probe and primer design with PRIMEGENS
GP Srivastava, D Xu
PCR Primer Design, 159-175, 2007
Meta-analysis of the human brain transcriptome identifies heterogeneity across human AD coexpression modules robust to sample collection and methodological approach
BA Logsdon, TM Perumal, V Swarup, M Wang, C Funk, C Gaiteri, M Allen, ...
BioRxiv, 510420, 2019
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