| Dimerization of complement factor H-related proteins modulates complement activation in vivo E Goicoechea de Jorge, JJE Caesar, TH Malik, M Patel, M Colledge, ... Proceedings of the National Academy of Sciences 110 (12), 4685-4690, 2013 | 302 | 2013 |
| Assembly and regulation of the membrane attack complex based on structures of C5b6 and sC5b9 MA Hadders, D Bubeck, P Roversi, S Hakobyan, F Forneris, BP Morgan, ... Cell reports 1 (3), 200-207, 2012 | 214 | 2012 |
| Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina SJ Clark, R Perveen, S Hakobyan, BP Morgan, RB Sim, PN Bishop, ... Journal of biological chemistry 285 (39), 30192-30202, 2010 | 203 | 2010 |
| Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions SJ Clark, LA Ridge, AP Herbert, S Hakobyan, B Mulloy, R Lennon, ... The Journal of Immunology 190 (5), 2049-2057, 2013 | 171 | 2013 |
| Complement activation in multiple sclerosis plaques: an immunohistochemical analysis G Ingram, S Loveless, OW Howell, S Hakobyan, B Dancey, CL Harris, ... Acta neuropathologica communications 2, 1-15, 2014 | 149 | 2014 |
| Complement in multiple sclerosis: its role in disease and potential as a biomarker G Ingram, S Hakobyan, NP Robertson, BP Morgan Clinical & Experimental Immunology 155 (2), 128-139, 2009 | 131 | 2009 |
| Identification of factor H–like protein 1 as the predominant complement regulator in Bruch’s membrane: Implications for age-related macular degeneration SJ Clark, CQ Schmidt, AM White, S Hakobyan, BP Morgan, PN Bishop The Journal of Immunology 193 (10), 4962-4970, 2014 | 129 | 2014 |
| Complement factor H binds to denatured rather than to native pentameric C-reactive protein S Hakobyan, CL Harris, CW Van Den Berg, MC Fernandez-Alonso, ... Journal of biological chemistry 283 (45), 30451-30460, 2008 | 118 | 2008 |
| Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration S Hakobyan, CL Harris, A Tortajada, EG De Jorge, A Garcia-Layana, ... Investigative ophthalmology & visual science 49 (5), 1983-1990, 2008 | 112* | 2008 |
| Epidermis instructs skin homing receptor expression in human T cells ML McCully, K Ladell, S Hakobyan, RE Mansel, DA Price, B Moser Blood, The Journal of the American Society of Hematology 120 (23), 4591-4598, 2012 | 108 | 2012 |
| Classical pathway complement activity in schizophrenia S Hakobyan, A Boyajyan, RB Sim Neuroscience letters 374 (1), 35-37, 2005 | 107 | 2005 |
| Complement regulator factor H as a serum biomarker of multiple sclerosis disease state G Ingram, S Hakobyan, CL Hirst, CL Harris, TP Pickersgill, MD Cossburn, ... Brain 133 (6), 1602-1611, 2010 | 96 | 2010 |
| Systemic complement profiling in multiple sclerosis as a biomarker of disease state G Ingram, S Hakobyan, CL Hirst, CL Harris, S Loveless, JP Mitchell, ... Multiple sclerosis journal 18 (10), 1401-1411, 2012 | 90 | 2012 |
| Variant-specific quantification of factor H in plasma identifies null alleles associated with atypical hemolytic uremic syndrome S Hakobyan, A Tortajada, CL Harris, SR De Córdoba, BP Morgan Kidney international 78 (8), 782-788, 2010 | 59 | 2010 |
| Complement biomarkers as predictors of disease progression in Alzheimer’s disease S Hakobyan, K Harding, M Aiyaz, A Hye, R Dobson, A Baird, B Liu, ... Journal of Alzheimer's Disease 54 (2), 707-716, 2016 | 50 | 2016 |
| Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder S Hakobyan, S Luppe, DRS Evans, K Harding, S Loveless, NP Robertson, ... Multiple Sclerosis Journal 23 (7), 946-955, 2017 | 48 | 2017 |
| Age-related macular degeneration and modification of systemic complement factor H production through liver transplantation S Khandhadia, S Hakobyan, LZ Heng, J Gibson, DH Adams, ... Ophthalmology 120 (8), 1612-1618, 2013 | 47 | 2013 |
| Distribution and determinants of circulating complement factor H concentration determined by a high-throughput immunonephelometric assay R Sofat, PP Mangione, JR Gallimore, S Hakobyan, TR Hughes, T Shah, ... Journal of immunological methods 390 (1-2), 63-73, 2013 | 41 | 2013 |
| Tissue microarray methodology identifies complement pathway activation and dysregulation in progressive multiple sclerosis S Loveless, JW Neal, OW Howell, KE Harding, P Sarkies, R Evans, ... Brain Pathology 28 (4), 507-520, 2018 | 40 | 2018 |
| Elevated plasma C4a levels in multiple sclerosis correlate with disease activity G Ingram, S Hakobyan, NP Robertson, BP Morgan Journal of neuroimmunology 223 (1-2), 124-127, 2010 | 35 | 2010 |
Paul N BishopEmeritus Professor of Ophthalmology & Matrix Biology, University of ManchesterVerified email at manchester.ac.uk
