Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides K Birsoy, R Possemato, FK Lorbeer, EC Bayraktar, P Thiru, B Yucel, ... Nature 508 (7494), 108-112, 2014 | 743 | 2014 |
Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death J Garcia-Bermudez, L Baudrier, EC Bayraktar, Y Shen, K La, ... Nature 567 (7746), 118-122, 2019 | 295 | 2019 |
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation RA Weber, FS Yen, SPV Nicholson, H Alwaseem, EC Bayraktar, M Alam, ... Molecular cell 77 (3), 645-655. e7, 2020 | 165 | 2020 |
Serine catabolism by SHMT2 is required for proper mitochondrial translation initiation and maintenance of formylmethionyl-tRNAs DR Minton, M Nam, DJ McLaughlin, J Shin, EC Bayraktar, SW Alvarez, ... Molecular cell 69 (4), 610-621. e5, 2018 | 152 | 2018 |
MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo EC Bayraktar, L Baudrier, C Özerdem, CA Lewis, SH Chan, T Kunchok, ... Proceedings of the National Academy of Sciences 116 (1), 303-312, 2019 | 87 | 2019 |
Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells WW Chen, K Birsoy, MM Mihaylova, H Snitkin, I Stasinski, B Yucel, ... Cell reports 7 (1), 27-34, 2014 | 81 | 2014 |
Metabolic coessentiality mapping identifies C12orf49 as a regulator of SREBP processing and cholesterol metabolism EC Bayraktar, K La, K Karpman, G Unlu, C Ozerdem, DJ Ritter, ... Nature metabolism 2 (6), 487-498, 2020 | 34 | 2020 |
Germline SDHA mutations in children and adults with cancer MD Gault, D Mandelker, D DeLair, CR Stewart, Y Kemel, MR Sheehan, ... Molecular Case Studies 4 (4), a002584, 2018 | 34 | 2018 |
Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability G Unlu, B Prizer, R Erdal, HW Yeh, EC Bayraktar, K Birsoy Molecular cell 82 (15), 2832-2843. e7, 2022 | 15 | 2022 |
Center, Cambridge, MA 02142, USA 6Present address: Boston Combined Residency Program, Department of Pediatrics, Boston Children’s Hospital, 300 Longwood Avenue, Boston, MA … EC Bayraktar, L Baudrier, C Özerdem, CA Lewis, S Ham | | |
FAK Is a Critical Mediator of GNAQ-Driven Uveal Melanoma J Garcia-Bermudez, L Baudrier, EC Bayraktar, Y Shen, K La, ... | | |