Interleukin 1 in the brain: biology, pathology and therapeutic target NJ Rothwell, GN Luheshi Trends in neurosciences 23 (12), 618-625, 2000 | 888 | 2000 |
The role of cytokines in mediating effects of prenatal infection on the fetus: implications for schizophrenia H Ashdown, Y Dumont, M Ng, S Poole, P Boksa, GN Luheshi Molecular psychiatry 11 (1), 47-55, 2006 | 481 | 2006 |
Leptin actions on food intake and body temperature are mediated by IL-1 GN Luheshi, JD Gardner, DA Rushforth, AS Loudon, NJ Rothwell Proceedings of the National Academy of Sciences 96 (12), 7047-7052, 1999 | 465 | 1999 |
The viral mimic, polyinosinic: polycytidylic acid, induces fever in rats via an interleukin-1-dependent mechanism ME Fortier, S Kent, H Ashdown, S Poole, P Boksa, GN Luheshi American Journal of Physiology-Regulatory, Integrative and Comparative …, 2004 | 416 | 2004 |
Dark microglia: a new phenotype predominantly associated with pathological states K Bisht, KP Sharma, C Lecours, M Gabriela Sánchez, H El Hajj, G Milior, ... Glia 64 (5), 826-839, 2016 | 374 | 2016 |
Cytokines and their receptors in the central nervous system: physiology, pharmacology, and pathology NJ Rothwell, G Luheshi, S Toulmond Pharmacology & therapeutics 69 (2), 85-95, 1996 | 310 | 1996 |
The vagus nerve mediates behavioural depression, but not fever, in response to peripheral immune signals; a functional anatomical analysis JP Konsman, GN Luheshi, RM Bluthé, R Dantzer European Journal of Neuroscience 12 (12), 4434-4446, 2000 | 287 | 2000 |
Circulating interleukin‐6 mediates the febrile response to localised inflammation in rats T Cartmell, S Poole, AV Turnbull, NJ Rothwell, GN Luheshi The Journal of physiology 526 (3), 653-661, 2000 | 276 | 2000 |
Effects of prenatal infection on prepulse inhibition in the rat depend on the nature of the infectious agent and the stage of pregnancy ME Fortier, GN Luheshi, P Boksa Behavioural brain research 181 (2), 270-277, 2007 | 273 | 2007 |
Obesity, adipokines and neuroinflammation A Aguilar-Valles, W Inoue, C Rummel, GN Luheshi Neuropharmacology 96, 124-134, 2015 | 227 | 2015 |
Maternal exposure to bacterial endotoxin during pregnancy enhances amphetamine-induced locomotion and startle responses in adult rat offspring MÈ Fortier, R Joober, GN Luheshi, P Boksa Journal of psychiatric research 38 (3), 335-345, 2004 | 218 | 2004 |
Prenatal infection leads to ASD-like behavior and altered synaptic pruning in the mouse offspring LF de Cossío, A Guzmán, S Van Der Veldt, GN Luheshi Brain, behavior, and immunity 63, 88-98, 2017 | 215 | 2017 |
Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type I receptor O Touzani, H Boutin, R LeFeuvre, L Parker, A Miller, G Luheshi, ... Journal of Neuroscience 22 (1), 38-43, 2002 | 208 | 2002 |
Expression of interleukin‐1 receptors and their role in interleukin‐1 actions in murine microglial cells E Pinteaux, LC Parker, NJ Rothwell, GN Luheshi Journal of neurochemistry 83 (4), 754-763, 2002 | 204 | 2002 |
Interleukin-1 receptor antagonist inhibits endotoxin fever and systemic interleukin-6 induction in the rat G Luheshi, AJ Miller, S Brouwer, MJ Dascombe, NJ Rothwell, SJ Hopkins American Journal of Physiology-Endocrinology and Metabolism 270 (1), E91-E95, 1996 | 198 | 1996 |
Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain C Rummel, C Sachot, S Poole, GN Luheshi American Journal of Physiology-Regulatory, Integrative and Comparative …, 2006 | 197 | 2006 |
Cytokines and fever: mechanisms and sites of action GN Luheshi Annals of the New York Academy of Sciences 856 (1), 83-89, 1998 | 188 | 1998 |
Role of neuroinflammation in the emotional and cognitive alterations displayed by animal models of obesity N Castanon, G Luheshi, S Layé Frontiers in neuroscience 9, 146137, 2015 | 170 | 2015 |
Circulating leptin mediates lipopolysaccharide‐induced anorexia and fever in rats C Sachot, S Poole, GN Luheshi The Journal of physiology 561 (1), 263-272, 2004 | 168 | 2004 |
Prenatal maternal stress exposure and immune function in the offspring F Veru, DP Laplante, G Luheshi, S King Stress 17 (2), 133-148, 2014 | 166 | 2014 |