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john alexander
john alexander
Cancer Bioinformatician, Institute of Cancer Research
Geverifieerd e-mailadres voor icr.ac.uk - Homepage
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Modelling mutational landscapes of human cancers in vitro
M Olivier, A Weninger, M Ardin, H Huskova, X Castells, MP Vallée, ...
Scientific reports 4 (1), 1-9, 2014
852014
17q21. 31 duplication causes prominent tau-related dementia with increased MAPT expression
K Le Guennec, O Quenez, G Nicolas, D Wallon, S Rousseau, AC Richard, ...
Molecular Psychiatry 22 (8), 1119-1125, 2017
492017
Clinical BRCA1/2 reversion analysis identifies hotspot mutations and predicted neoantigens associated with therapy resistance
SJ Pettitt, JR Frankum, M Punta, S Lise, J Alexander, Y Chen, TA Yap, ...
Cancer discovery 10 (10), 1475-1488, 2020
422020
Meta-analysis of Tourette Syndrome and Attention Deficit Hyperactivity Disorder provides support for a shared genetic basis
F Tsetsos, SS Padmanabhuni, J Alexander, I Karagiannidis, M Tsifintaris, ...
Frontiers in Neuroscience, 2016
332016
Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions
O Thompson, F von Meyenn, Z Hewitt, J Alexander, A Wood, ...
Nature communications 11 (1), 1-14, 2020
312020
Targeted re-sequencing approach of candidate genes implicates rare potentially functional variants in Tourette syndrome etiology
J Alexander, H Potamianou, J Xing, L Deng, I Karagiannidis, F Tsetsos, ...
Frontiers in neuroscience 10, 428, 2016
212016
Familial early-onset dementia with complex neuropathologic phenotype and genomic background
J Alexander, O Kalev, S Mehrabian, L Traykov, M Raycheva, D Kanakis, ...
Neurobiology of Aging 42, 199-204, 2016
162016
The genetics of Gilles de la Tourette syndrome: a common aetiological basis with comorbid disorders?
I Karagiannidis, F Tsetsos, SS Padmanabhuni, J Alexander, M Georgitsi, ...
Current Behavioral Neuroscience Reports 3 (3), 218-231, 2016
152016
Variant Ranker: a web-tool to rank genomic data according to functional significance
J Alexander, D Mantzaris, M Georgitsi, P Drineas, P Paschou
BMC bioinformatics 18 (1), 1-9, 2017
142017
TS-EUROTRAIN: a European-wide investigation and training network on the etiology and pathophysiology of Gilles de la Tourette syndrome
NJ Forde, AS Kanaan, J Widomska, SS Padmanabhuni, E Nespoli, ...
Frontiers in Neuroscience 10, 384, 2016
142016
Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis
U Jungwirth, A van Weverwijk, RJ Evans, L Jenkins, D Vicente, ...
Nature Communications 12 (1), 1-17, 2021
62021
The mutational concordance of fixed formalin paraffin embedded and fresh frozen gastro-oesophageal tumours using whole exome sequencing
IY Chong, N Starling, A Rust, J Alexander, L Aronson, ...
Journal of clinical medicine 10 (2), 215, 2021
42021
Sirtuin inhibition is synthetic lethal with BRCA1 or BRCA2 deficiency
I Bajrami, C Walker, DB Krastev, D Weekes, F Song, AJ Wicks, ...
Communications biology 4 (1), 1-16, 2021
32021
Assessment of the Molecular Heterogeneity of E-Cadherin Expression in Invasive Lobular Breast Cancer
J Alexander, O Mariani, C Meaudre, L Fuhrmann, H Xiao, K Naidoo, ...
Cancers 14 (2), 295, 2022
12022
ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype
H Sheldon, J Alexander, E Bridges, L Moreira, S Reilly, KH Ang, D Wang, ...
International journal of molecular sciences 22 (20), 11293, 2021
12021
Neuropathology-driven whole-genome sequencing study points to novel candidate genes for healthy brain aging
J Alexander, T Ströbel, M Georgitsi, S Hönigschnabl, A Reiner, P Fischer, ...
Alzheimer Disease & Associated Disorders 33 (1), 7-14, 2019
12019
Corrigendum: Modelling mutational landscapes of human cancers in vitro
M Olivier, A Weninger, M Ardin, H Huskova, X Castells, MP Vallée, ...
Scientific Reports 7, 2017
12017
Analysis of clinical BRCA1/2 reversions identifies hotspot mutations and predicted neoantigens associated with therapy resistance
S Pettitt, J Frankum, M Punta, S Lise, J Alexander, Y Chen, S Haider, ...
Cancer Research 80 (16 Supplement), 4072-4072, 2020
2020
Modelling mutational landscapes of human cancers in vitro (vol 4, 4482, 2017)
M Olivier, A Weninger, M Ardin, H Huskova, X Castells, MP Vallee, ...
SCIENTIFIC REPORTS 7, 2017
2017
Statistical methodology for the analysis of genomic data
J Alexander
Δημοκρίτειο Πανεπιστήμιο Θράκης (ΔΠΘ). Σχολή Επιστημών Υγείας. Τμήμα …, 2016
2016
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Artikelen 1–20