| Innovative approaches for designing and analyzing adaptive dose-ranging trials B Bornkamp, F Bretz, A Dmitrienko, G Enas, B Gaydos, CH Hsu, F König, ... Journal of biopharmaceutical statistics 17 (6), 965-995, 2007 | 221 | 2007 |
| Model‐based dose finding under model uncertainty using general parametric models J Pinheiro, B Bornkamp, E Glimm, F Bretz Statistics in medicine 33 (10), 1646-1661, 2014 | 182 | 2014 |
| Design and analysis of dose-finding studies combining multiple comparisons and modeling procedures J Pinheiro, B Bornkamp, F Bretz Journal of biopharmaceutical statistics 16 (5), 639-656, 2006 | 117 | 2006 |
| MCPMod: An R package for the design and analysis of dose-finding studies B Bornkamp, J Pinheiro, F Bretz Journal of Statistical Software 29, 1-23, 2009 | 100 | 2009 |
| A simulation study to compare new adaptive dose–ranging designs V Dragalin, B Bornkamp, F Bretz, F Miller, SK Padmanabhan, N Patel, ... Statistics in Biopharmaceutical Research 2 (4), 487-512, 2010 | 85 | 2010 |
| Bayesian nonparametric estimation of continuous monotone functions with applications to dose–response analysis B Bornkamp, K Ickstadt Biometrics 65 (1), 198-205, 2009 | 83 | 2009 |
| A practical guide to Bayesian group sequential designs T Gsponer, F Gerber, B Bornkamp, D Ohlssen, M Vandemeulebroecke, ... Pharmaceutical statistics 13 (1), 71-80, 2014 | 75 | 2014 |
| Advanced methods for dose and regimen finding during drug development: summary of the EMA/EFPIA workshop on dose finding (London 4–5 December 2014) FT Musuamba, E Manolis, N Holford, SYA Cheung, LE Friberg, ... CPT: pharmacometrics & systems pharmacology 6 (7), 418-429, 2017 | 70 | 2017 |
| DoseFinding: planning and analyzing dose finding experiments B Bornkamp, J Pinheiro, F Bretz R package version 0.4-1, 2010 | 66 | 2010 |
| Model selection versus model averaging in dose finding studies K Schorning, B Bornkamp, F Bretz, H Dette Statistics in medicine 35 (22), 4021-4040, 2016 | 63 | 2016 |
| truncnorm: Truncated normal distribution H Trautmann, D Steuer, O Mersmann, B Bornkamp R package version, 1.0-7, 2014 | 63 | 2014 |
| Response-adaptive dose-finding under model uncertainty B Bornkamp, F Bretz, H Dette, J Pinheiro The Annals of Applied Statistics, 1611-1631, 2011 | 63 | 2011 |
| Principal stratum strategy: potential role in drug development B Bornkamp, K Rufibach, J Lin, Y Liu, DV Mehrotra, S Roychoudhury, ... Pharmaceutical Statistics 20 (4), 737-751, 2021 | 59 | 2021 |
| Nonparametric bayesian networks K Ickstadt, B Bornkamp, M Grzegorczyk, J Wieczorek, MR Sheriff, ... Bayesian statistics 9, 283-316, 2010 | 47 | 2010 |
| Package ‘mvtnorm’ A Genz, F Bretz, T Miwa, X Mi, F Leisch, F Scheipl, B Bornkamp, ... Journal of Computational and Graphical Statistics 11 (950-971), 155, 2021 | 42 | 2021 |
| On the efficiency of two‐stage response‐adaptive designs H Dette, B Bornkamp, F Bretz Statistics in Medicine 32 (10), 1646-1660, 2013 | 41 | 2013 |
| Model averaging for treatment effect estimation in subgroups B Bornkamp, D Ohlssen, BP Magnusson, H Schmidli Pharmaceutical statistics 16 (2), 133-142, 2017 | 38 | 2017 |
| Adaptive and model-based dose-ranging trials: quantitative evaluation and recommendations. White paper of the PhRMA working group on adaptive dose-ranging studies J Pinheiro, F Sax, Z Antonijevic, B Bornkamp, F Bretz, C Chuang-Stein, ... Statistics in Biopharmaceutical Research 2 (4), 435-454, 2010 | 38 | 2010 |
| Functional uniform priors for nonlinear modeling B Bornkamp Biometrics 68 (3), 893-901, 2012 | 34 | 2012 |
| Retrospective Bayesian outlier detection in INGARCH series R Fried, I Agueusop, B Bornkamp, K Fokianos, J Fruth, K Ickstadt Statistics and Computing 25, 365-374, 2015 | 32 | 2015 |
Frank BretzNovartisVerified email at novartis.com
