| Analysis of numerical methods for computer simulation of kinetic processes: development of KINSIM—a flexible, portable system BA Barshop, RF Wrenn, C Frieden Analytical biochemistry 130 (1), 134-145, 1983 | 908 | 1983 |
| Kinetic aspects of regulation of metabolic processes: The hysteretic enzyme concept C Frieden Journal of Biological Chemistry 245 (21), 5788-5799, 1970 | 731 | 1970 |
| ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions PB Verghese, JM Castellano, K Garai, Y Wang, H Jiang, A Shah, G Bu, ... Proceedings of the National Academy of Sciences 110 (19), E1807-E1816, 2013 | 611 | 2013 |
| Glutamic dehydrogenase: II. The effect of various nucleotides on the association-dissociation and kinetic properties C Frieden Journal of Biological Chemistry 234 (4), 815-820, 1959 | 535* | 1959 |
| Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide X Hu, SL Crick, G Bu, C Frieden, RV Pappu, JM Lee Proceedings of the National Academy of Sciences 106 (48), 20324-20329, 2009 | 472 | 2009 |
| Glutamic dehydrogenase: I. The effect of coenzyme on the sedimentation velocity and kinetic behavior C Frieden Journal of Biological Chemistry 234 (4), 809-814, 1959 | 389 | 1959 |
| Slow transitions and hysteretic behavior in enzymes C Frieden Annual review of biochemistry 48 (1), 471-489, 1979 | 350 | 1979 |
| Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions SL Crick, M Jayaraman, C Frieden, R Wetzel, RV Pappu Proceedings of the National Academy of Sciences 103 (45), 16764-16769, 2006 | 326 | 2006 |
| Actin polymerization. The mechanism of action of cytochalasin D. DW Goddette, C Frieden Journal of Biological Chemistry 261 (34), 15974-15980, 1986 | 320 | 1986 |
| Treatment of enzyme kinetic data: I. The effect of modifiers on the kinetic parameters of single substrate enzymes C Frieden Journal of Biological Chemistry 239 (10), 3522-3531, 1964 | 302 | 1964 |
| Glutamate Dehydrogenase: V. The relation of enzyme structure to the catalytic function C Frieden Journal of Biological Chemistry 238 (10), 3286-3299, 1963 | 299 | 1963 |
| Protein-protein interaction and enzymatic activity C Frieden Annual review of biochemistry 40 (1), 653-696, 1971 | 296 | 1971 |
| Analysis of progress curves by simulations generated by numerical integration CT Zimmerle, C Frieden Biochemical Journal 258 (2), 381-387, 1989 | 281 | 1989 |
| Glutamic dehydrogenase: III. The order of substrate addition in the enzymatic reaction C Frieden Journal of Biological Chemistry 234 (11), 2891-2896, 1959 | 261 | 1959 |
| Climate change and the integrity of science PH Gleick, RM Adams, RM Amasino, E Anders, DJ Anderson, ... Science 328 (5979), 689-690, 2010 | 237 | 2010 |
| Unmasking the roles of N-and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation SL Crick, KM Ruff, K Garai, C Frieden, RV Pappu Proceedings of the National Academy of Sciences 110 (50), 20075-20080, 2013 | 224 | 2013 |
| PapD-like chaperones provide the missing information for folding of pilin proteins MM Barnhart, JS Pinkner, GE Soto, FG Sauer, S Langermann, ... Proceedings of the National Academy of Sciences 97 (14), 7709-7714, 2000 | 223 | 2000 |
| Treatment of Enzyme Kinetic Data: II. THE MULTISITE CASE: COMPARISON OF ALLOSTERIC MODELS AND A POSSIBLE NEW MECHANISM C Frieden Journal of Biological Chemistry 242 (18), 4045-4052, 1967 | 220 | 1967 |
| Protein aggregation processes: In search of the mechanism C Frieden Protein Science 16 (11), 2334-2344, 2007 | 207 | 2007 |
| Polymerization of actin: mechanism of the Mg2+-induced process at pH 8 and 20 degrees C. C Frieden Proceedings of the National Academy of Sciences 80 (21), 6513-6517, 1983 | 202 | 1983 |
