Umesh Jinwal
Umesh Jinwal
University of South Florida, Byrd Alzheimer’s Institute, College of Pharmacy
Verified email at health.usf.edu
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
7689*2016
Chemical manipulation of hsp70 ATPase activity regulates tau stability
UK Jinwal, Y Miyata, J Koren, JR Jones, JH Trotter, L Chang, J O'Leary, ...
Journal of Neuroscience 29 (39), 12079-12088, 2009
2332009
Akt and CHIP coregulate tau degradation through coordinated interactions
CA Dickey, J Koren, YJ Zhang, Y Xu, UK Jinwal, MJ Birnbaum, B Monks, ...
Proceedings of the National Academy of Sciences 105 (9), 3622-3627, 2008
2042008
Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation
JF Abisambra, UK Jinwal, LJ Blair, JC O'Leary, Q Li, S Brady, L Wang, ...
The Journal of Neuroscience 33 (22), 9498-9507, 2013
1842013
The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules
UK Jinwal, J Koren, SI Borysov, AB Schmid, JF Abisambra, LJ Blair, ...
The Journal of Neuroscience 30 (2), 591-599, 2010
1832010
Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden
JC O'Leary, Q Li, P Marinec, LJ Blair, EE Congdon, AG Johnson, ...
Molecular neurodegeneration 5 (1), 45, 2010
1752010
Allosteric drugs: the interaction of antitumor compound MKT-077 with human Hsp70 chaperones
A Rousaki, Y Miyata, UK Jinwal, CA Dickey, JE Gestwicki, ERP Zuiderweg
Journal of molecular biology 411 (3), 614-632, 2011
1632011
Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice
L Lebson, K Nash, S Kamath, D Herber, N Carty, DC Lee, Q Li, ...
The Journal of Neuroscience 30 (29), 9651-9658, 2010
1222010
Chaperone signalling complexes in Alzheimer's disease
J Koren, UK Jinwal, DC Lee, JR Jones, CL Shults, AG Johnson, ...
Journal of cellular and molecular medicine 13 (4), 619-630, 2009
1172009
1, 25-Dihydroxyvitamin D3 suppresses telomerase expression and human cancer growth through microRNA-498
R Kasiappan, Z Shen, KW Anfernee, U Jinwal, J Tang, P Lungchukiet, ...
Journal of Biological Chemistry 287 (49), 41297-41309, 2012
1142012
Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau
J Abisambra, UK Jinwal, Y Miyata, J Rogers, L Blair, X Li, SP Seguin, ...
Biological psychiatry 74 (5), 367-374, 2013
1032013
Imbalance of Hsp70 family variants fosters tau accumulation
UK Jinwal, E Akoury, JF Abisambra, JC O'Leary, AD Thompson, LJ Blair, ...
The FASEB Journal 27 (4), 1450-1459, 2013
1002013
Synthesis and initial evaluation of YM-08, a blood-brain barrier permeable derivative of the heat shock protein 70 (Hsp70) inhibitor MKT-077, which reduces tau levels
Y Miyata, X Li, HF Lee, UK Jinwal, SR Srinivasan, SP Seguin, ZT Young, ...
ACS chemical neuroscience 4 (6), 930-939, 2013
992013
A new anti-depressive strategy for the elderly: ablation of FKBP5/FKBP51
JC O'Leary III, S Dharia, LJ Blair, S Brady, AG Johnson, M Peters, ...
PloS one 6 (9), e24840, 2011
982011
Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice
JF Abisambra, LJ Blair, SE Hill, JR Jones, C Kraft, J Rogers, J Koren, ...
The Journal of Neuroscience 30 (46), 15374-15382, 2010
922010
Natural products as a rich source of tau-targeting drugs for Alzheimer's disease
L Calcul, B Zhang, UK Jinwal, CA Dickey, BJ Baker
Future medicinal chemistry 4 (13), 1751-1761, 2012
912012
Facilitating Akt clearance via manipulation of Hsp70 activity and levels
J Koren, UK Jinwal, Y Jin, J O'Leary, JR Jones, AG Johnson, LJ Blair, ...
Journal of Biological Chemistry 285 (4), 2498-2505, 2010
842010
Cysteine reactivity distinguishes redox sensing by the heat-inducible and constitutive forms of heat shock protein 70
Y Miyata, JN Rauch, UK Jinwal, AD Thompson, S Srinivasan, CA Dickey, ...
Chemistry & biology 19 (11), 1391-1399, 2012
812012
Hsc70 rapidly engages tau after microtubule destabilization
UK Jinwal, JC O'Leary, SI Borysov, JR Jones, Q Li, J Koren, JF Abisambra, ...
Journal of Biological Chemistry 285 (22), 16798-16805, 2010
802010
Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy
C Dickey, C Kraft, U Jinwal, J Koren, A Johnson, L Anderson, L Lebson, ...
The American journal of pathology 174 (1), 228-238, 2009
772009
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