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Ke Yu
Ke Yu
Alterome Therapeutics
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Year
Targeting KRAS mutant cancers with a covalent G12C-specific inhibitor
MR Janes, J Zhang, LS Li, R Hansen, U Peters, X Guo, Y Chen, A Babbar, ...
Cell 172 (3), 578-589. e17, 2018
9732018
Safety and pharmacokinetics of novel selective vascular endothelial growth factor receptor-2 inhibitor YN968D1 in patients with advanced malignancies
J Li, X Zhao, L Chen, H Guo, F Lv, K Jia, K Yv, F Wang, C Li, J Qian, ...
BMC cancer 10, 1-8, 2010
3142010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
M Chen, A Suzuki, S Thakkar, K Yu, C Hu, W Tong
Drug Discov Today 21 (4), 648-653, 2016
2842016
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia
S Klossowski, H Miao, K Kempinska, T Wu, T Purohit, EG Kim, ...
The Journal of clinical investigation 130 (2), 981-997, 2020
1622020
Absorption, disposition, and pharmacokinetics of saponins from Chinese medicinal herbs: what do we know and what do we need to know more?
K Yu, F Chen, C Li
Current drug metabolism 13 (5), 577-598, 2012
1612012
A metabonomic investigation on the biochemical perturbation in liver failure patients caused by hepatitis B virus
K Yu, G Sheng, J Sheng, Y Chen, W Xu, X Liu, H Cao, H Qu, Y Cheng, ...
Journal of proteome research 6 (7), 2413-2419, 2007
1172007
High daily dose and being a substrate of cytochrome P450 enzymes are two important predictors of drug-induced liver injury
K Yu, X Geng, M Chen, J Zhang, B Wang, K Ilic, W Tong
Drug Metabolism and Disposition 42 (4), 744-750, 2014
1112014
Quantitative analysis and chromatographic fingerprinting for the quality evaluation of Scutellaria baicalensis Georgi using capillary electrophoresis
K Yu, Y Gong, Z Lin, Y Cheng
Journal of Pharmaceutical and Biomedical Analysis 43 (2), 540-548, 2007
972007
Discriminating the genuineness of Chinese medicines using least squares support vector machines
K Yu, Y Cheng
Chinese Journal of Analytical Chemistry 34 (4), 561-564, 2006
542006
Simultaneous determination of eight active components in Chinese medicine ‘YIQING’capsule using high-performance liquid chromatography
H Qu, Y Ma, K Yu, Y Cheng
Journal of pharmaceutical and biomedical analysis 43 (1), 66-72, 2007
532007
Simultaneously determination of five ginsenosides in rabbit plasma using solid-phase extraction and HPLC/MS technique after intravenous administration of ‘SHENMAI’injection
K Yu, Y Ma, Q Shao, H Qu, Y Cheng
Journal of pharmaceutical and biomedical analysis 44 (2), 532-539, 2007
402007
Determination of paeonol and paeoniflorin in Chinese medicine Cortex Moutan and ‘Shuangdan’granule by micellar electrokinetic capillary chromatography
K Yu, YW Wang, YY Cheng
Journal of pharmaceutical and biomedical analysis 40 (5), 1257-1262, 2006
332006
Gas chromatography-mass spectrometry based on metabonomics study of carbon tetrachloride-induced acute liver injury in mice
H Xin, G Yi-Fei, Y Ke, C Yi-Yu
Chinese Journal of Analytical Chemistry 35 (12), 1736-1740, 2007
302007
Machine learning techniques for the prediction of the peptide mobility in capillary zone electrophoresis
K Yu, Y Cheng
Talanta 71 (2), 676-682, 2007
272007
Development of an HPLC–UV–ELSD Method for Quantification of Multiple Components of a Chinese Medicine Made from Radix salvia miltiorrhiza and Panax notoginseng
Y Lu, K Yu, HB Qu, YY Cheng
Chromatographia 65, 19-24, 2007
242007
Metabonomic analysis of hepatitis B virus-induced liver failure: identification of potential diagnostic biomarkers by fuzzy support vector machine
Y Mao, X Huang, K Yu, H Qu, C Liu, Y Cheng
Journal of Zhejiang University SCIENCE B 9 (6), 474-481, 2008
222008
Optimization of the buffer system of micellar electrokinetic capillary chromatography for the separation of the active components in Chinese medicine ‘SHUANGDAN’granule by …
K Yu, Z Lin, Y Cheng
Analytica chimica acta 562 (1), 66-72, 2006
222006
Pharmacokinetics and disposition of circulating iridoids and organic acids in rats intravenously receiving ReDuNing injection
C Cheng, F Du, K Yu, F Xu, F Wang, L Li, OE Olaleye, J Yang, F Chen, ...
Drug Metabolism and Disposition 44 (11), 1853-1858, 2016
212016
Determination of the active components in chinese herb cortex moutan by MEKC and LC
K Yu, YW Wang, YY Cheng
Chromatographia 63, 359-364, 2006
212006
Strategies for improving the quantitative bioanalytical performance of LC-MS in pharmacokinetic studies
L Li, D Tian, F Chen, J Yang, K Yu, Y Sun
Current drug metabolism 13 (9), 1206-1212, 2012
202012
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