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Ralph A Nixon
Ralph A Nixon
Professor of Psychiatry and Cell Biology New York University
Verified email at nki.rfmh.org
Title
Cited by
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, FC Abdalla, H Abeliovich, RT Abraham, A Acevedo-Arozena, ...
Autophagy 8 (4), 445-544, 2012
13054*2012
The role of autophagy in neurodegenerative disease
RA Nixon
Nature medicine 19 (8), 983-997, 2013
20862013
Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
C Janus, J Pearson, JA McLaurin, PM Mathews, Y Jiang, SD Schmidt, ...
Nature 408 (6815), 979-982, 2000
20182000
Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study
RA Nixon, J Wegiel, A Kumar, WH Yu, C Peterhoff, A Cataldo, AM Cuervo
Journal of Neuropathology & Experimental Neurology 64 (2), 113-122, 2005
17012005
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations
JH Lee, WH Yu, A Kumar, S Lee, PS Mohan, CM Peterhoff, DM Wolfe, ...
Cell 141 (7), 1146-1158, 2010
12382010
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
B Boland, A Kumar, S Lee, FM Platt, J Wegiel, WH Yu, RA Nixon
Journal of Neuroscience 28 (27), 6926-6937, 2008
12232008
Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
WH Yu, AM Cuervo, A Kumar, CM Peterhoff, SD Schmidt, JH Lee, ...
The Journal of cell biology 171 (1), 87-98, 2005
11532005
Alzheimer disease
DS Knopman, H Amieva, RC Petersen, G Chételat, DM Holtzman, ...
Nature reviews Disease primers 7 (1), 33, 2021
10592021
Endocytic pathway abnormalities precede amyloid β deposition in sporadic Alzheimer’s disease and Down syndrome: differential effects of APOE genotype and presenilin mutations
AM Cataldo, CM Peterhoff, JC Troncoso, T Gomez-Isla, BT Hyman, ...
The American journal of pathology 157 (1), 277-286, 2000
9132000
Autophagy, amyloidogenesis and Alzheimer disease
RA Nixon
Journal of cell science 120 (23), 4081-4091, 2007
8782007
Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration.
K Saito, JS Elce, JE Hamos, RA Nixon
Proceedings of the National Academy of Sciences 90 (7), 2628-2632, 1993
7261993
Autophagy failure in Alzheimer's disease—locating the primary defect
RA Nixon, DS Yang
Neurobiology of disease 43 (1), 38-45, 2011
6762011
Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration
A Salehi, JD Delcroix, PV Belichenko, K Zhan, C Wu, JS Valletta, ...
Neuron 51 (1), 29-42, 2006
6032006
Cdk5 is a key factor in tau aggregation and tangle formation in vivo
DK Noble W, Olm V, Takata K, Casey E, Mary O, Meyerson J, Gaynor K ...
Neuron 38 (4), 555-65, 2003
577*2003
Autophagy and its possible roles in nervous system diseases, damage and repair
DC Rubinsztein, M DiFiglia, N Heintz, RA Nixon, ZH Qin, B Ravikumar, ...
Autophagy 1 (1), 11-22, 2005
5432005
Enzymatically active lysosomal proteases are associated with amyloid deposits in Alzheimer brain.
AM Cataldo, RA Nixon
Proceedings of the National Academy of Sciences 87 (10), 3861-3865, 1990
5421990
Neurofilaments and neurofilament proteins in health and disease
A Yuan, MV Rao, RA Nixon
Cold Spring Harbor perspectives in biology 9 (4), a018309, 2017
5152017
Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer’s disease: neuropathologic evidence for a mechanism of increased β-amyloidogenesis
AM Cataldo, JL Barnett, C Pieroni, RA Nixon
Journal of Neuroscience 17 (16), 6142-6151, 1997
5101997
Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy
S Lee, Y Sato, RA Nixon
Journal of Neuroscience 31 (21), 7817-7830, 2011
5012011
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
DS Yang, P Stavrides, PS Mohan, S Kaushik, A Kumar, M Ohno, ...
Brain 134 (1), 258-277, 2011
4842011
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